Development and characterization of a system for temperature monitoring using photoacoustic images

• Grant number: 13/14416-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2013
• End date: July 31, 2014
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Theo Zeferino Pavan
• Grantee: João Henrique Uliana
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

The thermal technique is an alternative to surgery and can be used when the tumors are close to vital organs. The magnetic hyperthermia is a thermal technique based on interaction of magnetic nano-particles accumulated in the tumor region with the external alternating magnetic field. This procedure increases the temperature of the tumor region, destroying the tumor with minimum damage to healthy tissue. The temperature monitoring during treatment is important for patient safety and treatment success.A noninvasive way to monitor tissue temperature is through the photoacoustic image. The photoacoustic signal (produced from the interaction of short laser pulses with the tissue) is dependent on the mechanical and thermal properties of the tissue. It can be used for mapping tissue temperature. In this project will be developed and characterized a system for temperature monitoring using photoacoustic images during procedures that involve the interaction of alternating magnetic fields with magnetic particles.