Heart rate recovery after exercise: regulatory mechanisms in normotensives and hypertensives

• Grant number: 13/05519-4
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: December 01, 2013
• End date: November 30, 2016
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Cláudia Lúcia de Moraes Forjaz
• Grantee: Tiago Peçanha de Oliveira
• Host Institution: Escola de Educação Física e Esporte (EEFE). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 15/15466-0 - Post-exercise heart rate recovery: influence of thermoregulation, BE.EP.DR

Abstract

Post-exercise heart rate recovery (HRR) provides the assessment of the cardiac autonomic responsiveness to a physiological stress. Studies have been shown that reduced HRR values are associated with greater mortality risk. Hypertension is a high-prevalent disease with poor cardiovascular prognostic. Studies have shown a reduced HRR in hypertensive subjects compared to normotensive. This autonomic disturbance should reflect a lower efficiency of the cardiovascular autonomic mechanisms: central command, mechanoreflex, metaboreflex and thermoregulation. Nevertheless, the role and the impairment of these mechanisms on the HRR reduction in this population are not clear. The aim of this study, therefore, will be investigate the role of the cardiovascular control mechanisms on HRR of hypertensive. 25 hypertensive and 25 normotensive subjects will take part of 5 randomized experimental sessions. During the sessions, it will be done resting, exercise (cyclergometer, 30 min, 70% of maximal workload) and post-exercise recovery measures. The post-exercise recovery will be realized in different ways in each session: a) passive recovery - absence of movement; b) active recovery - maintaining the movement by the own voluntary with inferior intensity; c) assisted recovery - maintaining of the movement by a external force; d) passive recovery with circulatory occlusion and e) passive recovery with cooling ventilation. In all sessions, the eletrocardiographic, respiratory and photoplethysmography blood pressure signal will be continuously recorded. Moreover, the blood lactate concentration will be measured in specific moments. The two-by-two session comparisons will allow assessing the role of the mechanisms of cardiovascular autonomic regulation: central command (b vs. c), mechanoreflex (a vs. c), metaboreflex (a vs. d) and thermoregulation (a vc. e.) on HRR. The data will be analyzed by 2-way ANOVA for repeated measures, using as main factors the group and the session.

Scientific publications

(7)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PECANHA, TIAGO; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; SILVA, NATAN DANIEL; COUTO, PATRICIA GUIMARAES; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION, DECIO; LOW, DAVID A.; et al. Activation of Mechanoreflex, but not Central Command, Delays Heart Rate Recovery after Exercise in Healthy Men. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v. 42, n. 07, p. 602-609, JUN 2021. (13/04997-0, 13/05519-4)

PECANHA, TIAGO; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; DA SILVA JUNIOR, NATAN DANIEL; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION-JUNIOR, DECIO; DE MORAES FORJAZ, CLAUDIA LUCIA. Metaboreflex activation delays heart rate recovery after aerobic exercise in never-treated hypertensive men. JOURNAL OF PHYSIOLOGY-LONDON, v. 594, n. 21, p. 6211-6223, NOV 2016. (13/05519-4, 13/04997-0)

BRITO, LEANDRO; PECANHA, TIAGO; TINUCCI, TAIS; SILVA-JUNIOR, NATAN; COSTA, LUIZ; FORJAZ, CLAUDIA. Time of day affects heart rate recovery and variability after maximal exercise in pre-hypertensive men. CHRONOBIOLOGY INTERNATIONAL, v. 32, n. 10, p. 1385-1390, 2015. (13/05519-4, 11/03584-8, 13/04997-0)

PECANHA, TIAGO; FORJAZ, CLAUDIA L. M.; LOW, DAVID. A.. Additive effects of heating and exercise on baroreflex control of heart rate in healthy males. Journal of Applied Physiology, v. 123, n. 6, p. 1555-1562, DEC 2017. (15/15466-0, 13/05519-4)

PECANHA, TIAGO; LOW, DAVID; DE BRITO, LEANDRO CAMPOS; FECCHIO, RAFAEL YOKOYAMA; DE SOUSA, PATRICIA NASCIMENTO; DA SILVA-JUNIOR, NATAN DANIEL; DE ABREU, ANDREA PIO; DA SILVA, GIOVANIO VIEIRA; MION-JUNIOR, DECIO; FORJAZ, CLAUDIA LUCIA DE MORAES. Effects of postexercise cooling on heart rate recovery in normotensive and hypertensive men. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, v. 40, n. 2, DEC 2019. (15/15466-0, 13/04997-0, 13/05519-4)

PECANHA, TIAGO; DE MORAES FORJAZ, CLAUDIA L.; LOW, DAVID A.. Passive Heating Attenuates Post-exercise Cardiac Autonomic Recovery in Healthy Young Males. FRONTIERS IN NEUROSCIENCE, v. 11, DEC 21 2017. (13/05519-4)

PECANHA, TIAGO; FORJAZ, CLAUDIA; LOW, DAVID. Passive Heating Impairs Cardiac Autonomic Regulation during Exercise and Post-Exercise Recovery. FASEB JOURNAL, v. 31, p. 1-pg., 2017-04-01. (13/04997-0, 13/05519-4, 15/15466-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

OLIVEIRA, Tiago Peçanha de. Heart rate recovery after exercise: regulatory mechanisms in normotensives and hypertensives. 2016. Doctoral Thesis - Universidade de São Paulo (USP). Escola de Educação Física e Esportes (EEFE/BT) São Paulo.