Chemical incorporation of the antioxidant Trolox into a biodegradable polymer for controlled release

• Grant number: 13/19302-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2013
• End date: October 31, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Mauricio da Silva Baptista
• Grantee: Mariana Reis Nogueira de Lima
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 12/50680-5 - Photosensitization in life sciences, AP.TEM

Abstract

Sinthesize and characterize biocompatible and biodegradable polymer (Trolox poly(anhydride-ester)) containing the antioxidant Trolox chemical incorporated into a polymer backbone for controlled release in phisiological conditions in order to supress the oxidative stress. (AU)