Smoking affects the body homeostasis at various levels. The habit is connected to oral diseases, such as periodontitis, by negatively affect the host's immune system and to influence expression of virulence-associated genes in microorganisms periodontal pathogens. However, there is few reports about the influence of smoking on oral commensal microbiota. Objectives: To analyze the effect of cigarette smoke extract on cultures of oral commensal organism Streptococcus sanguinis. Materials and Methods: The effect of smoking on S. sanguinis will be assessed using the soluble components of cigarette smoke extract on microbial growth in culture, cell viability, ability to biofilm formation and expression of genes associated with virulence and IgA1 NT5.
News published in Agência FAPESP Newsletter about the scholarship: