Energy transfer peptide-lanthanides: optimization of antenna effect and application in biosensors

• Grant number: 14/05948-5
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: July 01, 2014
• End date: March 31, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Sidney José Lima Ribeiro
• Grantee: Lais Roncalho de Lima
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil

Abstract

The main goal of this work relies on the study of energy transfer processes between aminoacids and peptides and Ln3+ ions (Ln3+= Eu3+, Tb3+, Sm3+ and Nd3+). Natural and synthesized peptides will be studied with the main objective of optimization processes of light absorption and energy transfer by the adition of relevant species like triptophane and acridone. Hydrated ions, complexes and nanoparticles containing the active ions will be considered in the powder or self-assembled thin films. The light emission efficiency will be evaluated as a function of the energy position of the excited states and also the processing methods. The better understanding of energy transfer processes and the preparation of optimized compounds for bioanalyses and imaging applications are expected. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CORREALES, YORK E. SERGE; HAZRA, CHANCHAL; ULLAH, SAJJAD; LIMA, LAIS R.; RIBEIRO, SIDNEY J. L.. Precisely tailored shell thickness and Ln(3+) content to produce multicolor emission from Nd3+-sensitized Gd3+-based core/shell/shell UCNPs through bi-directional energy transfer. NANOSCALE ADVANCES, v. 1, n. 5, p. 1936-1947, MAY 1 2019. (14/05948-5, 15/22875-4, 15/18733-0, 18/15791-7)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LIMA, Lais Roncalho de. Energy transfer studies between peptides and lanthanides with biosensor applications. 2018. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Instituto de Química. Araraquara Araraquara.