Evaluation and analytical application of boron doped diamond porous electrodes for voltammetric determination of biomolecules, ascorbic acid, uric acid, dopamine and adrenaline in biological fluids and/or pharmaceutical formulations

• Grant number: 14/03019-7
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: August 01, 2014
• End date: June 30, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Orlando Fatibello Filho
• Grantee: Bruna Cláudia Lourenção
• Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil

Abstract

In recent years new carbon materials have been used as working electrode and have drawn attention due to the excellent results obtained.The films of porous boron doped diamond (BDD) are a new class of hybrid materials carbon and have potential relevance for applications in electroanalysis due to their interesting electrochemical properties. This hybrid material combines excellent conductivity and electron transport of the electrodes of carbon nanotubes (CNTs) with rugged surface of BDD films with high content of carbon sp3.The use of electroanalytical techniques for the determination of organic and inorganic compounds has grown significantly since it takes, accurate sensitive, low cost and require short analysis times and in many cases the simple preparation of samples.Thus, the aim of this study is to evaluate the analytical potential of a porous BDD electrode performing fundamental studies related to the electrochemical behavior of this, comparing it with conventional electrodes (BDD flat) and vertically aligned carbon nanotubes (VACNTs). Additionally, after evaluate of the use of the electrode for the determination of some important biomolecules whose electrochemical behavior is known, its can still be applied in the determination of compounds of interest (analytes) in environmental, pharmaceutical or food with the evaluation of analytical conditions for the development of a good procedure.Moreover, if necessary, these porous BDD electrodes can be modified with surface treatments as well as planar BDD to improve their analytical performance (analytical method) such as selectivity, sensitivity, precision, accuracy and reproducibility.

Scientific publications

(8)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

LAÍS PEREIRA SILVA; BRUNA C. LOURENCAO; ORLANDO FATIBELLO-FILHO. . Química Nova, v. 38, n. 6, p. 801-806, 2015-07-00. (14/03019-7)

LOURENCAO, BRUNA CLAUDIA; SILVA, TIAGO ALMEIDA; SANTOS, MAIARA DA SILVA; FERREIRA, ANTONIO GILBERTO; FATIBELLO-FILHO, ORLANDO. Sensitive voltammetric determination of hydroxyzine and its main metabolite cetirizine and identification of oxidation products by nuclear magnetic resonance spectroscopy. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 807, p. 187-195, DEC 15 2017. (14/03019-7)

LOURENCAO, BRUNA C.; MEDEIROS, ROBERTA A.; THOMASI, SERGIO SCHERRER; FERREIRA, ANTONIO GILBERTO; ROCHA-FILHO, ROMEU C.; FATIBELLO-FILHO, ORLANDO. Amperometric flow-injection determination of the anthelmintic drugs ivermectin and levamisole using electrochemically pretreated boron-doped diamond electrodes. SENSORS AND ACTUATORS B-CHEMICAL, v. 222, p. 181-189, JAN 2016. (09/17729-8, 14/03019-7, 11/00601-9)

BROCENSCHI, RICARDO F.; SILVA, TIAGO A.; LOURENCAO, BRUNA C.; FATIBELLO-FILHO, ORLANDO; ROCHA-FILHO, ROMEU C.. Use of a boron-doped diamond electrode to assess the electrochemical response of the naphthol isomers and to attain their truly simultaneous electroanalytical determination. Electrochimica Acta, v. 243, p. 374-381, JUL 20 2017. (14/11769-6, 14/03019-7, 16/03347-0)

LOURENCAO, BRUNA C.; MEDEIROS, ROBERTA A.; FATIBELLO-FILHO, ORLANDO. Simultaneous determination of antihypertensive drugs by flow injection analysis using multiple pulse amperometric detection with a cathodically pretreated boron-doped diamond electrode. Journal of Electroanalytical Chemistry, v. 754, p. 154-159, OCT 1 2015. (09/17729-8, 14/03019-7)

LOURENCAO, BRUNA C.; PINHEIRO, ROMARIO A.; SILVA, TIAGO A.; CORAT, EVALDO J.; FATIBELLO-FILHO, ORLANDO. Porous boron-doped diamond/CNT electrode as electrochemical sensor for flow-injection analysis applications. DIAMOND AND RELATED MATERIALS, v. 74, p. 182-190, APR 2017. (14/03019-7)

DEROCO, PATRICIA BATISTA; LOURENCAO, BRUNA CLAUDIA; FATIBELLO-FILHO, ORLANDO. The use of modified electrode with carbon black as sensor to the electrochemical studies and voltammetric determination of pesticide mesotrione. Microchemical Journal, v. 133, p. 188-194, JUL 2017. (14/07919-2, 14/03019-7)

LOURENCAO, BRUNA C.; MEDEIROS, ROBERTA A.; FATIBELLO-FILHO, ORLANDO. Simultaneous determination of antihypertensive drugs by flow injection analysis using multiple pulse amperometric detection with a cathodically pretreated boron-doped diamond electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 754, p. 6-pg., 2015-10-01. (09/17729-8, 14/03019-7)