Development, characterization and analytical applications of nanocomposites electrodes in catecholamines and flavonoids determination

• Grant number: 08/06867-8
• Support Opportunities: Regular Research Grants
• Duration: March 01, 2009 - February 28, 2011
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Ronaldo Censi Faria
• Grantee: Ronaldo Censi Faria
• Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil

Abstract

This project proposes the development of modified electrodes with nanocomposites prepared using nanomaterials and conducting polymers for determination of catecholamines and flavonoids in real and simulated samples. Single-walled and multi-walled carbon nanotubes and nanoparticles of gold and silver will be used as nanomaterials and the conducting polymers will be obtained using the monomers 1-aminoanthracene and 1-aminonaphtalene. Previous studies that used the poly-1-aminoanthracene showed good responses for dopamine without the interference of the ascorbic acid these results address the choice of the polymers that will be studies. The use of the nanocomposites has the objective of increasing the efficiency of the electronic transfer process and the electrocatalytic properties of the electrodes therefore sensors devices with better selectivity and detection limits can be obtained for the analytes that will be studied. Different strategies for constructed the nanocomposites electrodes will be evaluated and the electrodes obtained will be evaluated using the dopamine and ascorbic acid as a model system and after this the responses for the different analytes will be studied. The electrode that showed the best response for the proposed analytes will be evaluated with respect to the sensibility, selectivity, limit of detection and life time in real and simulated samples. The analytical responses of the nanocomposites electrodes will be evaluated for the determinations of catecholamines and flavonoids in pharmaceuticals formulations and in samples of food as green tea, wine and fruit juice, among others. The electrodes will be characterized by means of measurements of in situ mass variations using the quartz crystal microbalance and electrochemical impedance and by measurements of specular reflection infrared spectroscopy, scanning electronic microscopy and atomic force microscopy. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PESSOA-NETO, OSMUNDO D.; DOS SANTOS, VAGNER B.; VICENTINI, FERNANDO C.; SUAREZ, WILLIAN T.; ALONSO-CHAMARRO, JULIAN; FATIBELLO-FILHO, ORLANDO; FARIA, RONALDO C.. A low-cost automated flow analyzer based on low temperature co-fired ceramic and LED photometer for ascorbic acid determination. CENTRAL EUROPEAN JOURNAL OF CHEMISTRY, v. 12, n. 3, p. 341-347, MAR 2013. (11/02259-6, 08/06867-8)

TROIANI, ESTELA DE PIERI; FARIA, RONALDO CENSI. The Influence of the Cathodic Pretreatment on the Electrochemical Detection of Dopamine by Poly(1-aminoanthracene) Modified Electrode. Electroanalysis, v. 22, n. 19, p. 2284-2289, OCT 2010. (08/06867-8)

ALVES, CLAUDIA A.; PEDROSO, MARIELE M.; DE MORAES, MARCELA C.; SOUZA, DULCE H. F.; CASS, QUEZIA B.; FARIA, RONALDO C.. Real-time investigation of mannosyltransferase function of a Xylella fastidiosa recombinant GumH protein using QCM-D. Biochemical and Biophysical Research Communications, v. 408, n. 4, p. 571-575, MAY 20 2011. (08/06867-8)

TROIANI, ESTELA DE PIERI; PEREIRA-FILHO, EDENIR RODRIGUES; FARIA, RONALDO CENSI. Chemometric Strategies to Develop a Nanocomposite Electrode for Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid. Electroanalysis, v. 25, n. 8, p. 1988-1994, AUG 2013. (08/06867-8)

DA SILVA, QUESIA GUEDES; BARBOSA, NATHALIA VIEIRA; TROIANI, ESTELA DE PIERI; FARIA, RONALDO CENSI. Electrochemical Determination of Norepinephrine on Cathodically Pretreated Poly(1,5-diaminonaphthalene) Modified Electrode. Electroanalysis, v. 23, n. 6, p. 1359-1364, JUN 2011. (08/06867-8)

TROIANI, ESTELA DE PIERI; FARIA, RONALDO CENSI. Cathodically pretreated poly(1-aminoanthraquinone)-modified electrode for determination of ascorbic acid, dopamine, and uric acid. Journal of Applied Electrochemistry, v. 43, n. 9, p. 919-926, SEP 2013. (08/06867-8)