| Full text | |
| Author(s): |
Pessoa-Neto, Osmundo D.
[1]
;
dos Santos, Vagner B.
[1]
;
Vicentini, Fernando C.
[1]
;
Suarez, Willian T.
[2]
;
Alonso-Chamarro, Julian
[3]
;
Fatibello-Filho, Orlando
[1]
;
Faria, Ronaldo C.
[1]
Total Authors: 7
|
| Affiliation: | [1] Univ Fed Sao Carlos, Ctr Exact Sci & Technol, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Vicosa, Exact & Technol Sci Ctr, Dept Chem, BR-36570000 Vicosa, MG - Brazil
[3] Autonomous Univ Barcelona, Dept Chem, Grp Sensors & Biosensors, Bellaterra 08193 - Spain
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | CENTRAL EUROPEAN JOURNAL OF CHEMISTRY; v. 12, n. 3, p. 341-347, MAR 2013. |
| Web of Science Citations: | 5 |
| Abstract | |
An automated flow analyzer based on low temperature co-fired ceramic (LTCC), a solid-phase reactor (SPR) and a low-cost photometer was designed for ascorbic acid (AA) determination in pharmaceutical formulations. It consists of a peristaltic pump, three-way solenoid valves, SPR to chemically convert Cu(II) into Cu(I), and a LTCC device for mixing the liberated copper with bathocuproine and detection. The flow cell in the LTCC employed an ultrabright LED - photodiode photometer. The analyzer successfully determined AA in pharmaceutical formulations. The analytical curve from 8.5x10(-6) to 7.0x10(-4) M gave a detection limit of 7.0x10(-7) M and a RSD of 2.1% for a 2.0x10(-4) M AA solution (n = 10). A high sampling frequency of 102 h(-1) and low reagent and sample consumption (150 A mu L) resulted. (AU) | |
| FAPESP's process: | 11/02259-6 - Development of biosensors for determination of protein biomarkers to applied in early detection and monitoring of cancer |
| Grantee: | Ronaldo Censi Faria |
| Support Opportunities: | Scholarships abroad - Research |
| FAPESP's process: | 08/06867-8 - Development, characterization and analytical applications of nanocomposites electrodes in catecholamines and flavonoids determination |
| Grantee: | Ronaldo Censi Faria |
| Support Opportunities: | Regular Research Grants |