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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A low-cost automated flow analyzer based on low temperature co-fired ceramic and LED photometer for ascorbic acid determination

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Author(s):
Pessoa-Neto, Osmundo D. [1] ; dos Santos, Vagner B. [1] ; Vicentini, Fernando C. [1] ; Suarez, Willian T. [2] ; Alonso-Chamarro, Julian [3] ; Fatibello-Filho, Orlando [1] ; Faria, Ronaldo C. [1]
Total Authors: 7
Affiliation:
[1] Univ Fed Sao Carlos, Ctr Exact Sci & Technol, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil
[2] Univ Fed Vicosa, Exact & Technol Sci Ctr, Dept Chem, BR-36570000 Vicosa, MG - Brazil
[3] Autonomous Univ Barcelona, Dept Chem, Grp Sensors & Biosensors, Bellaterra 08193 - Spain
Total Affiliations: 3
Document type: Journal article
Source: CENTRAL EUROPEAN JOURNAL OF CHEMISTRY; v. 12, n. 3, p. 341-347, MAR 2013.
Web of Science Citations: 5
Abstract

An automated flow analyzer based on low temperature co-fired ceramic (LTCC), a solid-phase reactor (SPR) and a low-cost photometer was designed for ascorbic acid (AA) determination in pharmaceutical formulations. It consists of a peristaltic pump, three-way solenoid valves, SPR to chemically convert Cu(II) into Cu(I), and a LTCC device for mixing the liberated copper with bathocuproine and detection. The flow cell in the LTCC employed an ultrabright LED - photodiode photometer. The analyzer successfully determined AA in pharmaceutical formulations. The analytical curve from 8.5x10(-6) to 7.0x10(-4) M gave a detection limit of 7.0x10(-7) M and a RSD of 2.1% for a 2.0x10(-4) M AA solution (n = 10). A high sampling frequency of 102 h(-1) and low reagent and sample consumption (150 A mu L) resulted. (AU)

FAPESP's process: 11/02259-6 - Development of biosensors for determination of protein biomarkers to applied in early detection and monitoring of cancer
Grantee:Ronaldo Censi Faria
Support Opportunities: Scholarships abroad - Research
FAPESP's process: 08/06867-8 - Development, characterization and analytical applications of nanocomposites electrodes in catecholamines and flavonoids determination
Grantee:Ronaldo Censi Faria
Support Opportunities: Regular Research Grants