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Comparison of continuous and interval training on the perception of physical effort in health related quality of life and level of physical activity in asthma patients

Grant number: 14/16511-7
Support type:Scholarships in Brazil - Master
Effective date (Start): December 01, 2014
Effective date (End): November 30, 2015
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal researcher:Celso Ricardo Fernandes de Carvalho
Grantee:Patricia Gonçalves Leite Rocco
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:09/53904-9 - Effects of environment and lifestyle on asthma and chronic obstructive pulmonary disease: studies with experimental animals and people with asthma, AP.TEM


Physical exercise increases fitness and is associated with improved clinical management, quality of life, reduction of anxiety, depression and lung inflammation in asthmatic patients. However, little is understood about the best physical training provides greater benefits in these patients. Objectives: To compare the impact of aerobic training (AT) and interval (TI) in the perception of effort, health related quality of life and level of physical activity in asthma patients. Methods: 28 patients will be studied with moderate or severe persistent asthma who will be randomly assigned one of two groups: TA or TI. The physical training programs have a duration of 24 sessions (3 months), each session of exercise will last 40 minutes. The TA will have 5 min. heating, 30 min. exercise and 5 min. of slowdown, and will be based on the intensity aerobic capacity (VO2peak). TI will have 5 min. heating and carried out with 30 sec. of interval exercise with the same rest period between an initial intensity of 80 watts in power. Before exercise training programs, patients attend one of the educational program. Before and at the end of the intervention, patients will be evaluated for physical capacity (VO2max), clinical control (ACT, ACQ and symptom diary), health factors related to quality of life (AQLQ) and levels of anxiety and depression (HADS). Statistical analysis: The number of patients (28) was determined by sample size calculation. All statistical tests will be done with intention to treat. The normality of the data will be taken with the Shapiro-Wilks test. Continuous data will be analyzed with parametric tests (ANOVA and Bonferroni) or nonparametric (ANOVA on ranks and Mann-Whitney). For categorical data the chi-square test is applied. It will also be made of the effect size analysis. The significance level for all tests is 5% (p <0.05). (AU)

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