Development of nanostructured electrochemical sensors for the determination of antibiotics in samples of environmental interest

• Grant number: 14/11861-0
• Support Opportunities: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): December 01, 2014
• Effective date (End): February 28, 2018
• Field of knowledge: Engineering - Sanitary Engineering - Water Supply and Wastewater Treatment
• Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Marcos Roberto de Vasconcelos Lanza
• Grantee: Thais Tasso Guaraldo
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Associated research grant: 13/02762-5 - Development of technologies to prevent pollution: degradation and monitoring online of antibiotics in sewage, AP.JP
• Associated scholarship(s): 15/14100-2 - Nanomaterials synthesis using ionic liquids aiming electrochemical sensors development for pharmaceutical compounds detection, BE.EP.PD

Abstract

Environmental contamination by recalcitrant pollutants has been studied for many researchers all over the world. The increasing growth of industrial and human activities has strongly contributed to the environmental pollution. Pharmaceutical compounds have been founded as pollutants in residual water, underground water and soil mainly due to extensive elimination of these substances by the human body and animals after use. Moreover, its presence in aquatic environment may cause side effects to organisms as algae, crustaceans, bacteria and fish as well as human beings because of the acute toxicity of most pharmaceuticals. Toxic effects of antibiotics contamination as sulfonamides revealed normal development disturb, growing and bioaccumulation in different aquatic plants. Besides, it has caused huge impact on soil microbial community as bacterial resistance e inhibition of natural mechanism of natural pesticides contamination and other xenobiotics.Electroanalytical techniques have been pointed out for the many advantages of these methods as in situ measurement possibility, short analysis time, instrumentation and materials low cost, high sensitivity, miniaturization and portability. For these reason, they have been applied to many substances determination.However, one of the biggest challenges of this field is the development of novel materials with high stability which could be used as efficient sensors on antibiotics detection. Carbon nanotubes modified electrodes (CNTs) have been employed as sensors on electroanalysis due to advantages as electronic properties, high mechanical resistance and superficial areas. Moreover, CNTs have also been modified with metallic nanoparticles aiming better catalytic activity. The template synthesis has revealed an increase on sensors` sensitivity as it is able to generate highly reproducible materials with high surface area.Therefore, the present project aims to explore a novel materials synthesis method based on carbon nanotubes modification and metallic nanoparticles obtained by template synthesis which shows potential application as electrochemical sensors on antibiotics determination. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MARQUES CORDEIRO-JUNIOR, PAULO JORGE; GONCALVES, ROGER; GUARALDO, THAIS TASSO; PAIVA, ROBERT DA SILVA; PEREIRA, ERNESTO CHAVES; DE VASCONCELOS LANZA, MARCOS ROBERTO. Oxygen reduction reaction: Semi-empirical quantum mechanical and electrochemical study of Printex L6 carbon black. Carbon, v. 156, p. 1-9, JAN 2020. (14/11861-0, 14/50945-4, 11/14314-1, 17/10118-0, 16/01937-4, 16/19612-4)

VANESSA M. VASCONCELOS; FERNANDA DE L. SOUZA; THAIS T. GUARALDO; FERNANDA L. MIGLIORINI; MAURÍCIO R. BALDAN; NEIDENÊI G. FERREIRA; MARCOS R. DE V. LANZA. OXIDAÇÃO ELETROQUÍMICA DOS CORANTES REATIVOS PRETO 5 E AZUL 19 UTILIZANDO UM ELETRODO DE DIAMANTE DOPADO COM BORO NÃO COMERCIAL. Química Nova, v. 39, n. 9, p. 1051-1058, 2016-11-00. (11/15811-9, 14/11861-0, 13/15000-6)

GOULART, LORENA A.; GUARALDO, THAIS T.; LANZA, MARCOS R. V.. A Novel Electrochemical Sensor Based on Printex L6 Carbon Black Carrying CuO/Cu2O Nanoparticles for Propylparaben Determination. Electroanalysis, v. 30, n. 12, p. 2967-2976, DEC 2018. (17/10118-0, 14/50945-4, 14/11861-0, 16/08760-2, 16/01937-4)

GUARALDO, THAIS T.; GOULART, LORENA A.; MORAES, FERNANDO C.; LANZA, V, MARCOS R.. Carbon black nanospheres modified with Cu (II)-phthalocyanine for electrochemical determination of Trimethoprim antibiotic. Applied Surface Science, v. 470, p. 555-564, MAR 15 2019. (17/10118-0, 14/50945-4, 14/11861-0, 16/08760-2, 16/01937-4)