Evaluation of PCL electrospun fibers on the Ti-30Ta alloy surface after TiO2 nanotubes growth

• Grant number: 14/14533-3
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: March 01, 2015
• End date: February 28, 2017
• Field of knowledge: Engineering - Biomedical Engineering - Medical Engineering
• Agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Cecilia Amelia de Carvalho Zavaglia
• Grantee: Patricia Capellato
• Host Institution: Faculdade de Engenharia Mecânica (FEM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Over the last few years, several studies have been carried out in order to develop new materials for biomedical applications. Material surfaces that provide biomimetic morphology, such as nanoscale architectures, have been shown to alter cell/biomaterial interactions. The electrospinning process has been used for producing polymer fibers due in large part to an increased interest in nanoscale properties and technologies. The use of biocompatible polymers for the viability of cell growth is a promising alternative to improve osseointegration. The purpose of this study is the association of the electrospinning process of biocompatible polymer with TiO2 nanotubes on the Ti30Ta alloy surface. Characterization techniques such as SEM - FEG, X-rays, AFM, TGA, DSC and contact angle will be used for samples analyses. Bone marrow stromal cells (BMSCs) will also be used to investigate the short and long-term cellular response of these biomaterials to cellular adhesion, viability, morphology and proliferation. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PATRICIA CAPELLATO; LUCAS V. B. VASCONCELOS; FILIPE B. VILELA; GILZA CARLA RIBEIRO; CRISTIANE A. P. CORREIA; GILBERT SILVA; DANIELA SACHS; ANDRÉ L. R. RANGEL; CECILIA A. DE C. ZAVAGLIA; ANA P. R. ALVES CLARO. Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO2 Nanotubes: Effect on Microbial Activity. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 24, n. 6, 2021-10-27. (14/14533-3)

CAPELLATO, PATRICIA; SACHS, DANIELA; VILELA, FILIPE BUENO; MELO, MIRIAN M.; SILVA, GILBERT; RODRIGUES, GEOVANI; ZAVAGLIA, CECILIA A. DE C.; NAKAZATO, ROBERTO Z.; CLARO, ANA PAULA R. A.. Influence of Annealing Temperature on Corrosion Resistance of TiO(2)Nanotubes Grown on Ti-30Ta Alloy. METALS, v. 10, n. 8, AUG 2020. (14/14533-3)

CAPELLATO, PATRICIA; VASCONCELOS, LUCAS V. B.; VILELA, FILIPE B.; RIBEIRO, GILZA CARLA; CORREIA, CRISTIANE A. P.; SILVA, GILBERT; SACHS, DANIELA; RANGEL, ANDRE L. R.; ZAVAGLIA, CECILIA A. DE C.; ALVES CLARO, ANA P. R.. Titanium-Tantalum Alloy Surface Modification by Hydroxyapatite Layer on TiO Nanotubes: Effect on Microbial Activity. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 24, n. 6, 2021. (14/14533-3)

CAPELLATO, PATRICIA; VILELA, FILIPE BUENO; PALOMO FONTENELE, ANDRES HENRIQUE; SILVA, GILBERT; DA SILVA, KEROLENE BARBOZA; AQUILES CAROBOLANTE, JOAO PEDRO; MEDINA BEJARANO, EDWIN GILBERTO; NORONHA MOTTA MELO, MIRIAN DE LOURDES; ROSIFINI ALVES CLARO, ANA PAULA; SACHS, DANIELA. Evaluation of Microstructure and Mechanical Properties of a Ti10Mo8Nb Alloy for Biomedical Applications. METALS, v. 12, n. 7, p. 11-pg., 2022-07-01. (14/14533-3)

PATRICIA CAPELLATO; SAMIRA E. A. CAMARGO; GILBERT SILVA; DANIELA SACHS; FILIPE BUENO VILELA; CECILIA A. DE C. ZAVAGLIA; KETUL C. POPAT; ANA P.R. ALVES CLARO. Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization. MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, v. 23, n. 6, 2020-11-27. (14/14533-3)

CAPELLATO, PATRICIA; SACHS, DANIELA; VASCONCELOS, LUCAS V. B.; MELO, MIRIAM M.; SILVA, GILBERT; RANIERI, MARIA G. A.; ZAVAGLIA, CECILIA A. DE C.; NAKAZATO, ROBERTO Z.; ALVES CLARO, ANA P. R.. Optimization of Anodization Parameters in Ti-30Ta Alloy. METALS, v. 10, n. 8, AUG 2020. (14/14533-3)