Advanced search
Start date

Effect of desensitizing toothpastes in initial enamel erosion and abrasion

Grant number: 15/23620-0
Support type:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): March 01, 2016
Effective date (End): February 28, 2017
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal researcher:Ana Cecília Corrêa Aranha
Grantee:Samira Helena João de Souza
Supervisor abroad: Adrian Lussi
Home Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: University of Bern, Switzerland  
Associated to the scholarship:15/14117-2 - Hydraulic conductance and dentin tubular occlusion of different desensiting strategies for dentin hypersensitivity treatment, BP.DR


To investigate the effect of desensitizing toothpastes on initial enamel erosion and abrasion, 160 enamel samples from human third molars will be prepared. They will be randomly divided into 8 groups (n=20): (G1) deionized water; (G2) Colgate Cavity Protection; (G3) Regenerate; (G4) Colgate Pro Relief; (G5) Colgate Sensitive Original; (G6) Sensodyne Repair and Protection; (G7) Sensodyne Rapid Relief; (G8) Oral-B Sensi Relief. The specimens will be submitted to an erosion-abrasion cycling model of 8 days (1 cycle/day), which consists of incubation in artificial saliva (30 min), immersion in toothpaste slurry for 2 min, with toothbrush abrasion being performed for 10 s (20 toothbrush strokes), and erosion for 2 min, in 1% citric acid (pH = 3.6). Surface microhardness (SMH) and specular reflection will be measured at the beginning of the experiment. SMH will be remeasured after each abrasion and erosion treatment, and specular reflection will be remeasured at the end of each cycle. Enamel substance loss will be calculated after each abrasion. Statistical analyses will be performed considering a significant level of 5%.

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
JOAO-SOUZA, SAMIRA HELENA; SAKAE, LETICIA OBA; LUSSI, ADRIAN; CORREA ARANHA, ANA CECILIA; HARA, ANDERSON; BAUMANN, TOMMY; SCARAMUCCI, TAIS; CARVALHO, THIAGO SAADS. Toothpaste factors related to dentine tubule occlusion and dentine protection against erosion and abrasion. CLINICAL ORAL INVESTIGATIONS, . (15/23620-0)
JOAO-SOUZA, SAMIRA HELENA; LUSSI, ADRIAN; BAUMANN, TOMMY; SCARAMUCCI, TAIS; CORREA ARANHA, ANA CECILIA; CARVALHO, THIAGO SAADS. Chemical and physical factors of desensitizing and/or anti-erosive toothpastes associated with lower erosive tooth wear. SCIENTIFIC REPORTS, v. 7, . (15/23620-0)

Please report errors in scientific publications list by writing to: