In situ evaluation of a DENTRIFICE containing calcium silicate, phosphate and fluo...
Grant number: | 15/23620-0 |
Support type: | Scholarships abroad - Research Internship - Doctorate |
Effective date (Start): | March 01, 2016 |
Effective date (End): | February 28, 2017 |
Field of knowledge: | Health Sciences - Dentistry |
Principal Investigator: | Ana Cecília Corrêa Aranha |
Grantee: | Samira Helena João de Souza |
Supervisor abroad: | Adrian Lussi |
Home Institution: | Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo, SP, Brazil |
Local de pesquisa : | University of Bern, Switzerland |
Associated to the scholarship: | 15/14117-2 - Hydraulic conductance and dentin tubular occlusion of different desensiting strategies for dentin hypersensitivity treatment, BP.DR |
Abstract To investigate the effect of desensitizing toothpastes on initial enamel erosion and abrasion, 160 enamel samples from human third molars will be prepared. They will be randomly divided into 8 groups (n=20): (G1) deionized water; (G2) Colgate Cavity Protection; (G3) Regenerate; (G4) Colgate Pro Relief; (G5) Colgate Sensitive Original; (G6) Sensodyne Repair and Protection; (G7) Sensodyne Rapid Relief; (G8) Oral-B Sensi Relief. The specimens will be submitted to an erosion-abrasion cycling model of 8 days (1 cycle/day), which consists of incubation in artificial saliva (30 min), immersion in toothpaste slurry for 2 min, with toothbrush abrasion being performed for 10 s (20 toothbrush strokes), and erosion for 2 min, in 1% citric acid (pH = 3.6). Surface microhardness (SMH) and specular reflection will be measured at the beginning of the experiment. SMH will be remeasured after each abrasion and erosion treatment, and specular reflection will be remeasured at the end of each cycle. Enamel substance loss will be calculated after each abrasion. Statistical analyses will be performed considering a significant level of 5%. | |
Articles published in Agência FAPESP about the scholarship:Toothpaste alone does not prevent dental erosion or hypersensitivity | |