Effect of desensitizing toothpastes in initial enamel erosion and abrasion

• Grant number: 15/23620-0
• Support type: Scholarships abroad - Research Internship - Doctorate
• Effective date (Start): March 01, 2016
• Effective date (End): February 28, 2017
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal researcher: Ana Cecília Corrêa Aranha
• Grantee: Samira Helena João de Souza
• Supervisor abroad: Adrian Lussi
• Home Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Research place: University of Bern, Switzerland
• Associated to the scholarship: 15/14117-2 - Hydraulic conductance and dentin tubular occlusion of different desensiting strategies for dentin hypersensitivity treatment, BP.DR

Abstract

To investigate the effect of desensitizing toothpastes on initial enamel erosion and abrasion, 160 enamel samples from human third molars will be prepared. They will be randomly divided into 8 groups (n=20): (G1) deionized water; (G2) Colgate Cavity Protection; (G3) Regenerate; (G4) Colgate Pro Relief; (G5) Colgate Sensitive Original; (G6) Sensodyne Repair and Protection; (G7) Sensodyne Rapid Relief; (G8) Oral-B Sensi Relief. The specimens will be submitted to an erosion-abrasion cycling model of 8 days (1 cycle/day), which consists of incubation in artificial saliva (30 min), immersion in toothpaste slurry for 2 min, with toothbrush abrasion being performed for 10 s (20 toothbrush strokes), and erosion for 2 min, in 1% citric acid (pH = 3.6). Surface microhardness (SMH) and specular reflection will be measured at the beginning of the experiment. SMH will be remeasured after each abrasion and erosion treatment, and specular reflection will be remeasured at the end of each cycle. Enamel substance loss will be calculated after each abrasion. Statistical analyses will be performed considering a significant level of 5%.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

JOAO-SOUZA, SAMIRA HELENA; SAKAE, LETICIA OBA; LUSSI, ADRIAN; CORREA ARANHA, ANA CECILIA; HARA, ANDERSON; BAUMANN, TOMMY; SCARAMUCCI, TAIS; CARVALHO, THIAGO SAADS. Toothpaste factors related to dentine tubule occlusion and dentine protection against erosion and abrasion. CLINICAL ORAL INVESTIGATIONS, OCT 2019. Web of Science Citations: 0.

JOAO-SOUZA, SAMIRA HELENA; LUSSI, ADRIAN; BAUMANN, TOMMY; SCARAMUCCI, TAIS; CORREA ARANHA, ANA CECILIA; CARVALHO, THIAGO SAADS. Chemical and physical factors of desensitizing and/or anti-erosive toothpastes associated with lower erosive tooth wear. SCIENTIFIC REPORTS, v. 7, DEC 20 2017. Web of Science Citations: 3.