Clinal variation in immune-related genes of Drosophila melanogaster

• Grant number: 16/01354-9
• Support Opportunities: Scholarships in Brazil - Master
• Start date: March 01, 2016
• End date: August 31, 2018
• Field of knowledge: Biological Sciences - Genetics
• Principal Investigator: Rodrigo Cogni
• Grantee: Murillo Fernando Rodrigues
• Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 13/25991-0 - Ecological genomics of insects: climate adaptations and evolution of ecological interactions, AP.JP
• Associated scholarship(s): 17/06374-0 - Global patterns of natural variation in Drosophila melanogaster's immune genes, BE.EP.MS

Abstract

Selective pressures imposed by natural enemies may vary clinally, and the strongest pressure occurs in tropical regions. This spatial structure in selective forces may lead to the evolution of clines in polymorphisms related to resistance to natural enemies. The goal of this project is to investigate, with clinal variation, contemporaneous selection in genes of the Drosophila melanogaster immune system. Genomic data for natural populations distributed along a broad latitudinal transect was made available by previous studies; thus, it will be possible to examine the presence of clines in immune-related genes, comparing them to control genes without immune function.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RODRIGUES, MURILLO F.; COGNI, RODRIGO. Genomic Responses to Climate Change: Making the Most of the Drosophila Model. FRONTIERS IN GENETICS, v. 12, JUL 13 2021. (16/01354-9, 13/25991-0, 17/06374-0, 17/02206-6)

RODRIGUES, MURILLO F.; VIBRANOVSKI, MARIA D.; COGNI, RODRIGO. Clinal and seasonal changes are correlated in Drosophila melanogaster natural populations. Evolution, v. 75, n. 8, JUL 2021. (17/02206-6, 17/06374-0, 15/20844-4, 13/25991-0, 16/01354-9)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

RODRIGUES, Murillo Fernando. Adaptive or neutral clines? Integrating genome-wide clinal and seasonal variation to infer natural selection in Drosophila melanogaster. 2018. Master's Dissertation - Universidade de São Paulo (USP). Instituto de Biociências (IBIOC/SB) São Paulo.