Revisiting cDNA libraries

• Grant number: 16/13588-4
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: August 01, 2016
• End date: December 31, 2018
• Field of knowledge: Biological Sciences - Biochemistry - Molecular Biology
• Agreement: GlaxoSmithKline
• Principal Investigator: Ana Marisa Chudzinski-Tavassi
• Grantee: Flavio Lichtenstein
• Host Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 15/50040-4 - Rational approach for searching molecular targets involved in inflammatory events and cell survival, AP.PCPE

Abstract

Data available on cDNA transcriptomic libraries (Amblyomma cajennense, caterpillar Lonomia obliqua, leech Haementeria depressa, spider Loxoscelles laeta) will be revisited in order to: (i) identify potential compounds related to inflammatory and immunological processes of interest to the project, (ii) investigate previously identified molecules as "the hits" and (iii) evaluate the possibility of screening those sequences that have remained as "the hits". (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LICHTENSTEIN, FLAVIO; IQBAL, ASIF; ALVES DE LIMA WILL, SONIA ELISABETE; BOSCH, ROSEMARY VIOLA; DEOCESANO-PEREIRA, CARLOS; GOLDFEDER, MAURICIO BARBUGIANI; CHAMMAS, ROGER; MADUREIRA TRUFEN, CARLOS EDUARDO; PEREIRA MORAIS, KATIA LUCIANO; DE SOUZA, JEAN GABRIEL; et al. Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model. SCIENTIFIC REPORTS, v. 10, n. 1, APR 14 2020. (16/13588-4, 13/07467-1, 15/50040-4, 17/02052-9)