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CeTICS - Centro de Toxinas, Imuno-Resposta e Sinalização Celular

Processo: 13/07467-1
Modalidade de apoio:Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
Data de Início da vigência: 01 de julho de 2013
Data de Término da vigência: 30 de junho de 2026
Área do conhecimento:Ciências Biológicas - Bioquímica - Biologia Molecular
Pesquisador responsável:Hugo Aguirre Armelin
Beneficiário:Hugo Aguirre Armelin
Instituição Sede: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brasil
Pesquisadores principais:
( Atuais )		Denise Vilarinho Tambourgi ; Gisele Picolo ; Inácio de Loiola Meirelles Junqueira de Azevedo ; Monica Valdyrce dos Anjos Lopes Ferreira ; Solange Maria de Toledo Serrano ; Wilmar Dias da Silva
Pesquisadores principais:
( Anteriores )		Ana Marisa Chudzinski-Tavassi ; Junior Barrera ; Maria Carolina Quartim Barbosa Elias Sabbaga ; Osvaldo Augusto Brazil Esteves Sant'Anna ; Yara Cury
Pesquisadores associados:Adriana Mortara Almeida ; Alessandra Fernandes Bizerra ; Alexandre Keiji Tashima ; Aline Soriano Lopes ; Allan Mowat ; Ana Maria Moura da Silva ; Ana Marisa Chudzinski-Tavassi ; André Zelanis Palitot Pereira ; Ann Ager ; B. Paul Morgan ; Carla Cristina Squaiella ; Carla Lima da Silva ; Carmen W. Van Den Berg ; Daria Mochly-Rosen ; Denise Vilarinho Tambourgi ; Fabio Carlos Magnoli ; Fábio Nakano ; Fan Hui Wen ; Fernanda Calheta Vieira Portaro ; Fernanda Faria ; Fernanda Paiva Guimarães ; Gisele Picolo ; Giselle Pidde Marques Porto ; Inácio de Loiola Meirelles Junqueira de Azevedo ; Jay W. Fox ; Jesus Aparecido Ferro ; Jose Roberto Marcelino ; Jose Salvatore Leister Patane ; Julia Pinheiro Chagas da Cunha ; Katsuhiro Konno ; Kerly Fernanda Mesquita Pasqualoto ; Leo Kei Iwai ; Luc Pellerin ; Luciana Rodrigues Gomes ; Luiz Vicente Rizzo ; Marcella Barbosa Faria de Almeida Prado ; Marcelo da Silva Reis ; Marcelo de Franco ; Marcia Carvalho de Abreu Fantini ; Marcio Henrique Zaim ; Maria Carolina Quartim Barbosa Elias Sabbaga ; Maria Teresa Machini ; Marinilce Fagundes dos Santos ; Martha Marandino ; Miguel Allende ; Milton Yutaka Nishiyama Junior ; Mirta Schattner ; Miryam Paola Alvarez Flores ; Ovidiu Radulescu ; Paulo Lee Ho ; Paulo Sérgio Lacerda Beirão ; Pedro Ismael da Silva Junior ; Ricardo Jose Giordano ; Richard McCulloch ; Robson Lopes de Melo ; Roger Chammas ; Ruy Gastaldoni Jaeger ; Sandra Coccuzzo Sampaio Vessoni ; Silvio Roberto de Azevedo Salinas ; Simone Guedes Calderano ; Sonia Aparecida de Andrade Chudzinski ; Tânia Tomé Martins de Castro ; Vanessa Olzon Zambelli ; Vanessa Rioli
Auxílio(s) vinculado(s):20/01360-4 - Evolução do veneno de serpentes avançadas da América do Sul: uma abordagem integrada comparando linhagens cis-/trans-andinas, AV.EXT
22/10539-3 - EMU concedido no processo FAPESP 2013/07467-1: nome do equipamento: QuantStudio 3 Real-Time PCR System, Applied Biosystems, AP.EMU
19/23605-1 - Identificação de mecanismos moleculares de resistência a drogas e reparação de DNA em Trypanosomatidae, AP.R SPRINT
 + mais auxílios vinculados 21/13951-0 - EMU concedido no processo 13/07467-1 : Citômetro de Fluxo BD FACSLyric e acessórios, AP.EMU
21/13939-0 - EMU concedido no processo Fapesp 13/07467-1: Espectrômetro de Massas Orbitrap Exploris 480 e acessórios, AP.EMU
19/07809-6 - ICOM CECA Conference 2019: Roles of Museum Education: Supporting Self and Society, AR.EXT
18/26586-5 - 24o Congresso Mundial de Dermatologia, AR.EXT
17/18281-7 - EMU concedido no processo CEPID 2013/07467-1 - nome do equipamento: sistema NanoLC EASY-nLCTM 1000 - thermo scientific, AP.EMU
15/10413-6 - ICOM CECA Annual Conference 2015: Museum Education and Accessibility: Bridging the Gaps, AR.EXT
15/07553-0 - EMU concedido no processo 2013/07467-1: sistema de ressonância plasmônica de superfície - Biacore T200, AP.EMU
15/10037-4 - EMU concedido no processo 2013/07467-1: citômetro de fluxo, AP.EMU - menos auxílios vinculados
Bolsa(s) vinculada(s):25/05104-6 - Implantação de método para avaliação da eficiência de edição gênica, BP.TT
24/16448-5 - Avaliação da ativação do inflamassoma pela proteína Natterina-like codificada pelo gene loc795232 em zebrafish, BP.DD
24/18730-0 - Implementação de cultura celular 3D para "screening" de compostos com potencial antitumoral, BP.TT
 + mais bolsas vinculadas 24/04901-7 - Eficácia e potencial preventivo da apitoxina e da melitina na farmacoacupuntura para controle da dor neuropática: Avaliação da segurança, determinação dos mecanismos envolvidos e busca de fragmentos ativos, BP.DR
24/17031-0 - Contribuições do Sistema Complemento e Células Endoteliais na Imunopatologia dos Envenenamentos por Abelhas Africanizadas (Apis mellifera), BP.PD
24/18492-1 - Análise proteômica dos efeitos do veneno de Bothrops jararaca sobre Sangue Humano Total., BP.TT
24/14508-0 - Apoio técnico aos projetos de genômica do CeTICS: sequenciamento e montagem de genomas ofídicos, BP.TT
24/09407-0 - Nova proposta terapêutica para o câncer: combinação de mitogeno com um inibidor de via de estresse celular., BP.PD
24/09408-7 - Explorar o balanço entre ativação mitogênica e inibição de vias de estresse em células cancerígenas e normais, BP.PD
24/03396-7 - Aprendizagem profunda para predição e caracterização estrutural de toxinas glicosiladas de serpentes do gênero Bothrops, BP.DD
23/17619-5 - O veneno de Bothrops jararaca e a falência renal: bases moleculares da toxicidade sobre células mesangiais e tecido renal murino, do efeito sinérgico de produtos de degradação de proteínas plasmáticas, e o papel de catepsinas, BP.DD
23/12213-0 - Gerenciamento e Implementação de novas ferramentas para a plataforma CeTICSDB., BP.TT
23/10147-0 - Avaliação dos mecanismos moleculares de Natterina-like XP_017212453.1 que facilitam a ativação do inflamassoma em larvas de zebrafish, BP.PD
23/08327-0 - O veneno de Bothrops jararaca e o dano tecidual: análise proteômica e peptidômica da toxicidade em fibroblastos humanos., BP.IC
23/01659-8 - Avaliação da ativação do inflamassoma pela proteína Natterina-like codificada pelo gene loc795232 em zebrafish, BP.MS
23/00140-9 - Análise proteômica de pulmão de camundongos sob o efeito da peçonha de Crotalus durissus terrificus, BP.IC
23/04095-8 - Gerenciamento e Implementação de novas ferramentas para a plataforma CeTICSDB, BP.TT
22/07209-1 - O veneno de Bothrops jararaca e a falência renal: bases moleculares da citotoxicidade em células mesangiais e do efeito sinérgico de produtos de degradação de proteínas plasmáticas., BP.MS
22/16146-3 - Caracterização molecular dos efeitos do veneno de Bothrops jararaca: análise de células pulmonares em cultura e tecido pulmonar de camundongo por abordagens proteômica e imuno-histoquímica., BP.PD
22/10761-8 - Influência da tríade, grupo heme/sistema complemento/inflamação, na imunopatogênese do envenenamento por abelhas africanizadas, BP.TT
21/10570-5 - Caracterização molecular dos efeitos in vivo do veneno da Bothrops jararaca: análises do tecido muscular e do plasma de camundongos, por abordagens de proteômica e imuno-histoquímica, BP.PD
21/10344-5 - Identificação de peptídeos derivados da crotoxina com potencial antitumoral e imunomodulatório, BP.PD
19/24580-2 - Seleção bayesiana de modelos dinâmicos de vias não isoladas de sinalização celular, BP.DD
21/08891-8 - Avaliação dos mecanismos farmacológicos do peptídeo TnP isolado do veneno de Thalassophryne nattereri na terapêutica da Retinopatia Hipóxica em Zebrafish, BP.PD
21/04355-4 - Implementações eficientes de métodos Bayesianos para seleção de modelos de vias de sinalização celular, BP.IC
20/11468-7 - Gerenciamento e Implementação de Novas Ferramentas para a Plataforma CeTICSDB, BP.TT
20/12317-2 - Análise proteômica dos efeitos sistêmicos do veneno da Bothrops jararaca em modelo murino., BP.PD
19/27348-3 - Inibição do sistema complemento como meio para controlar a inflamação associada a envenenamentos, BP.PD
20/03718-3 - Compreendendo as reações locais induzidas pelos venenos de Loxosceles e suas principais toxinas, BP.PD
20/00770-4 - Síntese de derivados de benznidazol e óxido de grafeno e avaliação de suas atividades anti-chagásicas, BP.PD
19/27677-7 - Estudo da indução de microRNAs regulatórios por TNP dependente da ativação do receptor de hidrocarboneto arílico (AhR), BP.PD
19/20025-4 - Uma abordagem baseada em computação Bayesiana aproximada para resolver o problema da falta de isolamento na modelagem de vias de sinalização, BE.PQ
19/18565-0 - Avaliação por hibridização in situ quantitativa dos níveis dos transcritos de natterina-like em zebrafish depletados com CRISPR/Cas-9, BP.IC
19/10500-7 - Avaliação da necessidade da ativação do complexo inflamassoma na inflamação neutrofilica induzida pelas natterinas, toxinas formadoras de poros, BE.PQ
19/05882-8 - Avaliação do papel da crotalfina na dinâmica do cílio primário de neurônios aferentes primários: novos caminhos para o estudo de compostos analgésicos, BP.PD
19/13039-9 - Controle do Ciclo Celular em células normais e malignas, nova abordagem na terapia do câncer., BP.PD
19/01895-8 - Função das nucleases MRE11, DNA2 e EXO1 na ressecção do DNA terminal e o reparo das quebras de dupla fita em Trypanosoma brucei, BP.PD
19/02333-3 - Validação da importância funcional das natterinas na resposta imune inata em zebrafish por CRISPR-Cas9, um método de loss-of-function, BP.MS
18/06751-1 - Caracterização molecular dos efeitos in vivo da metaloproteinase hemorrágica HF3: análises do proteoma do tecido muscular de camundongos, BP.MS
18/12364-0 - Expressão, purificação e caracterização inicial de uma nova proteína RPA-like de Trypanosoma brucei, BP.IC
17/07693-2 - Dinâmica funcional da proteína Orc1b durante o ciclo de vida de Trypanosoma, BP.DR
18/08167-5 - Apoio bioinformático aos projetos de análise de expressão gênica diferencial do CeTICS, BP.TT
18/06682-0 - Análise filogenética computacional de serpentes do gênero Bothrops a partir de proteomas de venenos, BP.IC
17/06496-9 - Caracterização proteômica do efeito da peçonha de Bothrops jararaca sobre linhagens celulares de câncer versus linhagens celulares normais, BP.MS
17/20575-9 - Identificação de vias de sinalização celular baseada em repositórios de cinética de reações bioquímicas, BP.MS
17/18344-9 - Proteômica quantitativa da cromatina frente ao tratamento com FGF2: análise da regulação transcricional e associação de cdc42, BP.DD
17/19252-0 - Análise proteômica dos efeitos de PA-BJ, uma serinoproteinase do veneno de Bothrops jararaca, sobre cultura de células endoteliais de sangue periférico, BP.PD
17/19545-8 - Análise dos mecanismos moleculares subjacentes à inibição do ciclo celular por FGF2 em células Y1 adrenocorticais e tumorais de camundongo, dependentes de WT-Kras amplificado, BP.PD
17/09929-3 - Venenos de serpentes do gênero Bothrops: impacto da glicosilação na complexidade dos proteomas e função de toxinas, BP.DD
17/12199-7 - Loxoscelismo: da pesquisa básica ao desenvolvimento de novas terapias, BP.TT
17/13681-7 - Análise e desenvolvimento de ferramentas de bioinformática aplicadas a estudos de genômica, transcriptômica e proteômica, BP.TT
17/09648-4 - Expressão recombinante, e caracterização funcional dos domínios não catalíticos de uma metaloproteinase da classe P-III do veneno da serpente Bothrops jararaca, utilizando um sistema de expressão livre de célula, BP.IC
17/10853-1 - Desenvolvimento de ferramentas e análises para estudo das bases moleculares para a replicação do DNA e ciclo celular, BP.TT
16/25959-7 - Projeto de algoritmos baseados em florestas de posets para o problema de otimização U-curve, BP.IC
16/22774-6 - Controle epigenético na analgesia dependente da ativação de receptores opióides: papel dos miRNAs e metilação do DNA no efeito antinociceptivo da crotalfina, BP.PD
17/02225-0 - Loxoscelismo: da pesquisa básica ao desenvolvimento de novas terapias, BP.TT
16/25661-8 - Desenvolvimento de infraestrutura e ferramentas de análise e integração de dados de genômica e transcriptômica para Bothrops jararaca no projeto CeTICS, BP.TT
17/00715-0 - Enzimas proteolíticas de venenos de serpentes disparam cascatas de eventos moleculares ainda desconhecidos, BP.PD
16/17775-3 - Desenho e simulação de modelos computacionais da dinâmica de replicação de DNA em Kinetoplastídeos, BP.IC
16/22415-6 - Desenvolvimento de infraestrutura e ferramentas de análise e integração de dados de genômica e transcriptômica para Bothrops jararaca no projeto CeTICS, BP.TT
16/16935-7 - Uma perspectiva sobre as modificações pós-traducionais em toxinas de venenos do gênero Bothrops: identificação proteômica de sítios específicos de N-glicanos e cisteínas., BP.DR
16/13469-5 - Desenvolvimento de Infraestrutura, ferramentas de análise e integração de dados de genômica e transcriptômica no projeto CeTICS, BP.TT
15/12224-6 - Avaliação dos mecanismos envolvidos na sobrevivência de células de longa vida produtoras de anticorpos induzida pela IL-17 externalizada em NET (neutrophil extracellular traps), BE.PQ
16/10613-8 - Análise da ação do sistema complemento na expressão de micro RNAs no loxoscelismo sistêmico, BP.PD
16/07802-3 - Concepção de antivenenos com base na sequência de aminoácidos das regiões determinantes de complementaridade (CDRs), BP.PD
15/23691-4 - Ativ pró-inflamatória de proteinases de venenos de serpentes: i) obtenção de proteinases recombinantes em sistema livre de CEL; ii) geração de microvesículas por monócitos estimulados com proteinases nativas e recomb e sua interação com células endoteliais, BP.PD
15/17053-5 - Estudo da ativação de inflamassomas, em queratinócitos humanos, por ação do veneno da aranha Loxosceles laeta e sua esfingomielinase D, BP.PD
15/03509-7 - Sequenciamento genômico de serpentes brasileiras focado no estudo de toxinas, BP.PD
15/17494-1 - Loxoscelism: from basic research to the proposal of new therapies, BP.PD
15/01234-0 - Enzimas proteolíticas de venenos de serpentes disparam cascatas de eventos moleculares ainda desconhecidos, BP.PD
15/04641-6 - Investigação da participação da dessensibilização de receptores no antagonismo das natterinas, BP.IC
14/24170-5 - Dinâmica da replicação do DNA em Trypanosoma cruzi: caracterização do licenciamento e da taxa de replicação, BP.PD
15/03953-4 - Modulação da expressão de integrinas em neutrófilos pelas Natterinas, BP.IC
14/02978-0 - Análise funcional do complexo RPA em Trypanosoma cruzi e seu envolvimento com DNA telomérico, BP.DR
14/23564-0 - Estudos de estruturas de dados eficientes para abordar o problema de otimização U-curve, BP.IC
14/21557-6 - Analise funcional dos homólogos Ataxia-telangiectasia mutated (ATM) e a Ataxia-telangiectasia and RAD3-related (ATR) na sinalização de dano ao DNA em Trypanosoma cruzi, BP.IC
14/18875-6 - Dor e analgesia: mecanismos moleculares de novas drogas terapêuticas e alvos, BP.PD
14/13375-5 - Origens da replicação em tripanossomas, BP.PD
14/01534-1 - Caracterização do potencial de inibição do receptor de colágeno receptor do domínio de Discoidina 2 por componentes de metaloproteinases de venenos de cobra, BE.PQ
13/24212-7 - Bioinformática e modelagem, BP.PD
13/50694-9 - Avaliação do papel dos NET de neutrófilos na diferenciação de células produtoras de anticorpos de longa vida na resposta crônica induzida pelo veneno de Thalassophryne nattereri, BP.PD
13/07974-0 - Sequenciamento do genoma da serpente Bothrops jararaca para caracterização da estrutura gênica de toxinas e seus elementos regulatórios, BP.DR
12/51135-0 - Verificação da indução pelas natterinas de mecanismos reguladores da cascata de sinalização de TLR, BP.PD
12/20186-9 - Mecanismos moleculares da interação funcional entre Ras e ciclina D1 em células malignas dependentes de Ras, BP.PD
11/09333-7 - Crotalfina: análogos fluorescentes e estudo de seu mecanismo de ação em culturas e co-culturas de neurônios e queratinócitos, BP.PD - menos bolsas vinculadas
Assunto(s):Ciclo celular  Homeostase  Toxinas  Genes de resposta imune  Financiamento em saúde 
Palavra(s)-Chave do Pesquisador:biologia sistêmica | ciclo celular | homeostasia | resposta imune | sinalização celular | toxina | Biologia Molecular
Publicação FAPESP:https://media.fapesp.br/bv/uploads/pdfs/Multidisciplinary_science_Ebmcxc8_18_19.pdf

Resumo

No Instituto Butantan toxinologia e regulação da resposta imune são, tradicionalmente, áreas conexas de pesquisa científica e desenvolvimento biotecnológico, através das quais o Instituto, historicamente, construiu sua reputação internacional de excelência. Na cultura do Instituto, venenos são misturas complexas de toxinas, selecionadas ao longo da evolução para sinergicamente exercerem efeitos biológicos sistêmicos, através de mecanismos bioquímicos, moleculares e celulares altamente específicos. Portanto, a análise química de venenos tem boas chances de levar à descoberta de novas moléculas de toxinas com potencial terapêutico. Essas premissas foram seguidas com sucesso por pesquisadores do Centro de Toxinologia Aplicada (CAT CEPID-FAPESP), projeto iniciado há 10 anos, que isolaram, caracterizaram quimicamente e patentearam diversas toxinas de natureza proteica, que se tornaram pontos de partida para desenvolvimento de inovação farmacêutica em parceria com indústrias locais. A ênfase em proteínas e peptídeos levou o CAT CEPID a instalar laboratórios no estado da arte para transcriptômica, proteômica, biologia molecular do DNA recombinante e síntese de peptídeos. Mais recentemente, estudos dos mecanismos de ação, bioquímicas, moleculares e celulares, dessas promissoras moléculas foram iniciados com o objetivo de estabelecer provas de conceito. Assim, o CAT estabeleceu, no Instituto Butantan, as condições iniciais para a criação de um centro de toxinas e resposta imune fundamentado nas abordagens atuais da biologia sistêmica. Por conseguinte, 10 pesquisadores, entre os mais competitivos do Instituto Butantan, propõem a criação do novo Centro de Toxinas, Resposta-imune e Sinalização Celular, com aspirações a centro de excelência de classe mundial, aproveitando a histórica reputação internacional do Butantan e o sucesso recente do CAT CEPID. O Plano de pesquisa do Centro Integra subprojetos voltados para a pesquisa científica com subprojetos de vocação para a inovação tecnológica. Um grande grupo de cientistas seniores do Instituto Butantan, de outras instituições brasileiras e de renomadas instituições estrangeiras serão colaboradores do Centro proposto. (AU)

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Publicações científicas (308)
(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)
MONTE, ELISABETE R. C.; ROSSATO, CRISTIANO; LLANOS, RICARDO PARIONA; RUSSO, LILIAN C.; DE CASTRO, LEANDRO M.; GOZZO, FABIO C.; DE ARAUJO, CHRISTIANE B.; PERON, JEAN PIERRE S.; SANT'ANNA, OSVALDO AUGUSTO; FERRO, EMER S.; et al. Interferon-gamma activity is potentiated by an intracellular peptide derived from the human 19S ATPase regulatory subunit 4 of the proteasome. JOURNAL OF PROTEOMICS, v. 151, n. SI, p. 74-82, . (13/07467-1)
CALDERANO, SIMONE GUEDES; NISHIYAMA JUNIOR, MILTON YUTAKA; MARINI, MARJORIE; NUNES, NATHAN DE OLIVEIRA; REIS, MARCELO DA SILVA; PATANE, JOSE SALVATORE LEISTER; DA SILVEIRA, JOSE FRANCO; DA CUNHA, JULIA PINHEIRO CHAGAS; ELIAS, MARIA CAROLINA. Identification of Novel Interspersed DNA Repetitive Elements in the Trypanosoma cruzi Genome Associated with the 3 ` UTRs of Surface Multigenic Families. GENES, v. 11, n. 10, . (13/07467-1, 16/50050-2)
LUND, PEDER J.; LOPES, MARIANA; SIDOLI, SIMONE; CORADIN, MARIEL; DE LUNA VITORINO, FRANCISCA NATHALIA; CHAGAS DA CUNHA, JULIA PINHEIRO; GARCIA, BENJAMIN A.. FGF-2 induces a failure of cell cycle progression in cells harboring amplified K-Ras, revealing new insights into oncogene-induced senescence. MOLECULAR OMICS, . (11/22619-7, 16/24881-4, 17/15835-1, 18/15553-9, 15/04867-4, 17/18344-9, 13/07467-1)
LIMA, GUILHERME M.; MENEZES, MILENE C.; COSTA, IRIS M.; SERRANO, SOLANGE M. T.; MONTEIRO, GISELE. Development of a cell-free protein synthesis protocol to rapidly screen L-asparaginase proteoforms by enzymatic activity. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, . (13/08617-7, 18/15041-8, 16/25896-5, 13/07467-1, 18/15104-0)
SOUZA, GLAUCIA MENDES; VAN SLUYS, MARIE-ANNE; LEMBKE, CAROLINA GIMILIANI; LEE, HAYAN; MARGARIDO, GABRIEL RODRIGUES ALVES; HOTTA, CARLOS TAKESHI; GAIARSA, JONAS WEISSMANN; DINIZ, AUGUSTO LIMA; OLIVEIRA, MAURO DE MEDEIROS; FERREIRA, SAVIO DE SIQUEIRA; et al. Assembly of the 373k gene space of the polyploid sugarcane genome reveals reservoirs of functional diversity in the world's leading biomass crop. GIGASCIENCE, v. 8, n. 12, . (13/07467-1, 13/18322-4, 17/02842-0, 08/52074-0, 14/50921-8, 15/22993-7, 12/51062-3, 17/02270-6, 11/50761-2, 16/17545-8, 16/06917-1, 13/23048-9, 08/52146-0, 15/15346-5)
GLORIA MARIA DA SILVA; DANIEL HENRIQUE BERTO DE SOUZA; KAROLINE B. WAITMAN; MATTEO CELANO EBRAM; MELISSA R. FESSEL; IULIU CEZAR ZAINESCU; FERNANDA C. PORTARO; MONTSE HERAS; SONIA A. DE ANDRADE. Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, . (13/07467-1, 17/04321-7)
ROBERTO TADASHI KODAMA; ALEXANDRE KAZUO KUNIYOSHI; CRISTIANE CASTILHO FERNANDES DA SILVA; DANIELA CAJADO-CARVALHO; BRUNO DUZZI; DOUGLAS CEOLIN MARIANO; DANIEL C. PIMENTA; RAFAEL BORGES; WILMAR DIAS DA SILVA; FERNANDA CALHETA VIEIRA PORTARO. A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 26, . (15/13124-5, 11/02061-1, 13/15344-7, 13/07467-1, 15/15364-3)
NORTON FELIPE DOS SANTOS SILVA; PEDRO LUIZ MAILHO-FONTANA; PEDRO ISMAEL DA SILVA-JUNIOR; JOSÉ ROBERTO MACHADO CUNHA DA SILVA; RODRIGO HIRATA WILLEMART. Morphology of the arthrodial membrane gland in a Neotropical harvester (Arachnida: Opiliones). Zoologia, v. 40, . (13/07467-1, 20/05158-5)
GIRARD, RICHARD M. B. M.; CRISPIM, MARCELL; STOLIC, IVANA; DAMASCENO, FLAVIA SILVA; DA SILVA, MARCELO SANTOS; FURUSHO PRAL, EIZABETH MIEKO; ELIAS, MARIA CAROLINA; BAJIC, MIROSLAV; SILBER, ARIEL MARIANO. An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells. Antimicrobial Agents and Chemotherapy, v. 60, n. 10, p. 5867-5877, . (13/07467-1, 13/18970-6)
AUGUSTO-DE-OLIVEIRA, CESAR; STUGINSKI, DANIEL R.; KITANO, EDUARDO S.; ANDRADE-SILVA, DEBORA; LIBERATO, TARCISIO; FUKUSHIMA, ISABELLA; SERRANO, SOLANGE M. T.; ZELANIS, ANDRE. Dynamic Rearrangement in Snake Venom Gland Proteome: Insights into Bothrops jararaca Intraspecific Venom Variation. JOURNAL OF PROTEOME RESEARCH, v. 15, n. 10, p. 3752-3762, . (13/07467-1, 15/18096-0, 14/06579-3)
BOSCH, ROSEMARY VIOLA; ALVAREZ-FLORES, MIRYAM PAOLA; MARIA, DURVANEI AUGUSTO; CHUDZINSKI-TAVASSI, ANA MARISA. Hemolin triggers cell survival on fibroblasts in response to serum deprivation by inhibition of apoptosis. BIOMEDICINE & PHARMACOTHERAPY, v. 82, p. 537-546, . (13/07467-1, 15/50040-4, 13/06892-0, 08/54092-5)
VALENTE, RICHARD HEMMI; LUNA, MILENE SCHMIDT; DE OLIVEIRA, URSULA CASTRO; NISHIYAMA-JUNIOR, MILTON YUTAKA; JUNQUEIRA-DE-AZEVEDO, INACIO DE LOIOLA; PORTES-JUNIOR, JOSE ANTONIO; CLISSA, PATRICIA BIANCA; VIANA, LUCIANA GODOY; SANCHES, LEONARDO; MOURA-DA-SILVA, ANA MARIA; et al. Bothrops jararaca accessory venom gland is an ancillary source of toxins to the snake. JOURNAL OF PROTEOMICS, v. 177, p. 137-147, . (13/07467-1, 07/50083-9, 14/26058-8, 16/50127-5)
PAVANI, RAPHAEL SOUZA; VITARELLI, MARCELA O.; FERNANDES, CARLOS A. H.; MATTIOLI, FABIO F.; MORONE, MARIANA; MENEZES, MILENE C.; FONTES, MARCOS R. M.; CANO, MARIA ISABEL N.; ELIAS, MARIA CAROLINA. Replication Protein A-1 Has a Preference for the Telomeric G-rich Sequence in Trypanosoma cruzi. Journal of Eukaryotic Microbiology, v. 65, n. 3, p. 345-356, . (13/07467-1, 15/10580-0, 14/02978-0)
DE LIMA, LOYZE P.; POUBEL, SALOE BISPO; YUAN, ZUO-FEI; ROSON, JULIANA NUNES; DE LUNA VITORINO, FRANCISCA NATHALIA; HOLETZ, FABIOLA BARBIERI; GARCIA, BENJAMIN A.; CHAGAS DA CUNHA, JULIA PINHEIRO. Improvements on the quantitative analysis of Trypanosoma cruzi histone post translational modifications: Study of changes in epigenetic marks through the parasite's metacyclogenesis and life cycle. JOURNAL OF PROTEOMICS, v. 225, . (18/21785-0, 17/06104-3, 18/14432-3, 18/15553-9, 13/07467-1, 17/18344-9)
ASEGA, AMANDA F. .; MENEZES, MILENE C.; TREVISAN-SILVA, DILZA; CAJADO-CARVALHO, DANIELA; BERTHOLIM, LUCIANA; OLIVEIRA, ANA K.; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. SCIENTIFIC REPORTS, v. 10, n. 1, . (17/00715-0, 10/00206-0, 17/19252-0, 10/17328-0, 11/08514-8, 13/07467-1)
SILVA DE FRANCA, FELIPE; VILLAS-BOAS, ISADORA MARIA; COGLIATI, BRUNO; WOODRUFF, TRENT M.; REIS, EDIMARA DA SILVA; LAMBRIS, JOHN D.; TAMBOURGI, DENISE V.. C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera. FRONTIERS IN IMMUNOLOGY, v. 12, . (13/07467-1)
ANDRADE-SILVA, DEBORA; NISHIYAMA JR, MILTON Y.; STUGINSKI, DANIEL R.; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.. The distinct N-terminomes of Bothrops jararaca newborn and adult venoms. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1869, n. 7, . (16/16935-7, 13/07467-1, 13/14651-3)
SEGURA-RAMIREZ, PAULA J.; DE GODOY, PEDRO MACHADO; AVINO, IVAN N.; SILVA JUNIOR, PEDRO I.. Encrypted antimicrobial peptides from proteins present in the plasma of the millipede Rhinocricus sp.. JOURNAL OF PROTEOMICS, v. 242, . (13/07467-1)
LOPES, PRISCILA HESS; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; MARQUES, MARIO OCTAVIO THA; TAMBOURGI, DENISE V.. Clinical aspects, diagnosis and management of Loxosceles spider envenomation: literature and case review. ARCHIVES OF TOXICOLOGY, v. 94, n. 5, . (13/07467-1, 15/17053-5)
LIMA, CARLA; FALCAO, MARIA ALICE PIMENTEL; PINTO, FELIPE JUSTINIANO; BERNARDO, JEFFERSON THIAGO GONCALVES; LOPES-FERREIRA, MONICA. The Anti-Inflammatory Peptide TnP Is a Candidate Molecule for Asthma Treatment. CELLS, v. 12, n. 6, p. 15-pg., . (13/07467-1)
ROSA, JOAO GABRIEL SANTOS; LOPES-FERREIRA, MONICA; LIMA, CARLA. An Overview towards Zebrafish Larvae as a Model for Ocular Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 6, p. 21-pg., . (13/07467-1, 21/08891-8)
SANT'ANNA, MORENA BRAZIL; GIARDINI, ALINE C.; RIBEIRO, MARCIO A. C.; LOPES, FLAVIA S. R.; TEIXEIRA, NATHALIA B.; KIMURA, LOUISE F.; BUFALO, MICHELLE C.; RIBEIRO, ORLANDO G.; BORREGO, ANDREA; CABRERA, WAFA H. K.; et al. The Crotoxin:SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions. FRONTIERS IN IMMUNOLOGY, v. 11, . (17/17844-8, 15/01254-1, 14/19397-0, 13/07467-1)
MEGALE, ANGELA ALICE AMADEU; PORTARO, FERNANDA CALHETA; DA SILVA, WILMAR DIAS. Bitis arietans Snake Venom Induces an Inflammatory Response Which Is Partially Dependent on Lipid Mediators. TOXINS, v. 12, n. 9, . (13/07467-1)
HAUZMAN, EINAT; PIEROTTI, MICHELE E. R.; BHATTACHARYYA, NIHAR; TASHIRO, JULIANA H.; YOVANOVICH, CAROLA A. M.; CAMPOS, POLLYANNA F.; VENTURA, DORA F.; CHANG, BELINDA S. W.. imultaneous Expression of UV and Violet SWS1 Opsins Expands the Visual Palette in a Group of Freshwater Snake. Molecular Biology and Evolution, v. 38, n. 12, p. 5225-5240, . (18/11502-0, 14/26818-2, 18/13910-9, 14/25743-9, 18/09321-8, 13/07467-1, 15/14857-6)
AOUNALLAH, HAJER; FESSEL, MELISSA REGINA; GOLDFEDER, MAURICIO BARBUGIANI; CARVALHO, ENEAS; BENSAOUD, CHAIMA; CHUDZINSKI-TAVASSI, ANA MARISA; BOUATTOUR, ALI; M'GHIRBI, YOUMNA; FARIA, FERNANDA. Dromaserpin: A Novel Anti-Hemostatic Serpin, from the Salivary Glands of the Hard Tick Hyalomma dromedari. TOXINS, v. 13, n. 12, . (13/07467-1)
NISHIYAMA-JR, MILTON Y.; TASHIMA, ALEXANDRE K.; NISHIDUKA, ERIKA S.; ABREU, THIAGO F.; ABUKAWA, FERNANDA MIDORI; OLIVEIRA, URSULA C.; TARDIVO, CAIO E. O.; NASCIMENTO, SORAIA M.; MEISSNER, GABRIEL O.; CHAIM, OLGA M.; et al. Multiomics Profiling of Toxins in the Venom of the Amazonian Spider Acanthoscurria juruenicola. JOURNAL OF PROTEOME RESEARCH, v. 21, n. 11, p. 15-pg., . (17/20106-9, 18/13588-0, 13/07467-1)
BRAS-COSTA, CAROLINA; CHAVES, ALISON FELIPE ALENCAR; TREVISAN-SILVA, DILZA; MENEZES, MILENE C.; ROCHA, MARISA M. T.; CAJADO-CARVALHO, DANIELA; ANDRADE-SILVA, DEBORA; SERRANO, SOLANGE M. T.. Sialic acid-containing glycans play a role in the activity of snake venom proteases. Biochimie, v. 204, p. 14-pg., . (13/13548-4, 13/07467-1, 15/23017-1, 17/09929-3)
DIAZ-ROA, ANDREA; ESPINOZA-CULUPU, ABRAHAM; TORRES-GARCIA, ORLANDO; BORGES, MONAMARIS M.; AVINO, IVAN N.; ALVES, FLAVIO L.; MIRANDA, ANTONIO; PATARROYO, MANUEL A.; DA SILVA, JR., PEDRO I.; BELLO, FELIO J.. Sarconesin II, a New Antimicrobial Peptide Isolated from Sarconesiopsis magellanica Excretions and Secretions. Molecules, v. 24, n. 11, . (13/07467-1)
DOS SANTOS, JULIANE MONTEIRO; DOS SANTOS, JANAINA CARDOSO; MARQUES, ELINEIDE EUGENIO; DE ARAUJO, GESSI CARVALHO; SEIBERT, CARLA SIMONE; LOPES-FERREIRA, MONICA; CARLA, LIMA. Stingray (Potamotrygon rex) maturity is associated with inflammatory capacity of the venom. Toxicon, v. 163, p. 74-83, . (13/07467-1)
GONCALVES LUCHINI, LYGIA SAMARTIN; PIDDE, GISELLE; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; TAMBOURGI, DENISE V.. Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase. FRONTIERS IN IMMUNOLOGY, v. 10, . (13/07467-1, 13/26198-1)
GREN, ERIC C. K.; KITANO, EDUARDO S.; ANDRADE-SILVA, DEBORA; IWAI, LEO KEI; REIS, MARCELO S.; MENEZES, MILENE C.; SERRANO, SOLANGE M. T.. Comparative analysis of the high molecular mass subproteomes of eight Bothrops snake venoms. Comparative Biochemistry and Physiology D-Genomics & Proteomics, v. 30, p. 113-121, . (13/07467-1, 15/01234-0, 13/13548-4)
KUNIYOSHI, ALEXANDRE KAZUO; KODAMA, ROBERTO TADASHI; CAJADO-CARVALHO, DANIELA; IWAI, LEO KEI; KITANO, EDUARDO; FERNANDES DA SILVA, CRISTIANE CASTILHO; DUZZI, BRUNO; DA SILVA, WILMAR DIAS; PORTARO, FERNANDA CALHETA. Experimental antivenom against serine proteases from the Bothrops jararaca venom obtained in mice, and its comparison with the antibothropic serum from the Butantan Institute. Toxicon, v. 169, p. 59-67, . (15/13124-5, 13/07467-1, 13/15344-7, 12/06677-0, 15/15364-3)
SILVA, LUIZ E.; SOUZA, RENAN C.; KITANO, EDUARDO S.; MONTEIRO, LUCAS F.; IWAI, LEO K.; FORTI, FABIO L.. Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3 eta as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability. JOURNAL OF PROTEOME RESEARCH, v. 18, n. 10, p. 3597-3614, . (13/07467-1, 08/58264-5, 18/01753-6)
DE OLIVEIRA, URSULA CASTRO; NISHIYAMA, JR., MILTON YUTAKA; VIANA DOS SANTOS, MARIA BEATRIZ; SANTOS-DA-SILVA, ANDRIA DE PAULA; CHALKIDIS, HIPOCRATES DE MENEZES; SOUZA-IMBERG, ANDREIA; CANDIDO, DENISE MARIA; YAMANOUYE, NORMA; CORONADO DORCE, VALQUIRIA ABRAO; MEIRELLES JUNQUEIRA-DE-AZEVEDO, INACIO DE LOIOLA. Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. PLoS One, v. 13, n. 3, . (13/07467-1)
RIBEIRO, KLEBER SILVA; VASCONCELLOS, CAMILLA IOSHIDA; SOARES, RODRIGO PEDRO; MENDES, MARIA TAYS; ELLIS, CAMERON C.; AGUILERA-FLORES, MARCELA; DE ALMEIDA, IGOR CORREIA; SCHENKMAN, SERGIO; IWAI, LEO KEI; TORRECILHAS, ANA CLAUDIA. Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells. JOURNAL OF EXTRACELLULAR VESICLES, v. 7, n. 1, . (13/07467-1)
ESPINOZA-CULUPU, ABRAHAM; MENDES, ELIZABETH; VITORINO, HECTOR AGUILAR; DA SILVA JR, PEDRO ISMAEL; BORGES, MONAMARIS MARQUES. Mygalin: An Acylpolyamine With Bactericidal Activity. FRONTIERS IN MICROBIOLOGY, v. 10, . (14/04307-6, 13/11212-9, 13/07467-1)
MOREIRA, RAFAEL J.; CASTRO, ERIQUE; OLIVEIRA, TIAGO E.; BELCHIOR, THIAGO; PEIXOTO, ALBERT S.; CHAVES-FILHO, ADRIANO B.; MORENO, MAYARA F.; LIMA, JANAYNA D.; YOSHINAGA, MARCOS; MIYAMOTO, SAYURI; et al. Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. MOLECULAR NUTRITION & FOOD RESEARCH, v. 64, n. 7, . (13/07467-1, 16/04000-3, 17/17943-6, 15/19530-5, 14/06863-3, 18/15549-1, 13/07937-8)
LOPES, PRISCILA HESS; VAN DEN BERG, CARMEN W.; TAMBOURGI, V, DENISE. Sphingomyelinases D From Loxosceles Spider Venoms and Cell Membranes: Action on Lipid Rafts and Activation of Endogenous Metalloproteinases. FRONTIERS IN PHARMACOLOGY, v. 11, . (13/07467-1, 15/17053-5)
OLIVEIRA, DANIELLE B. L.; DURIGON, GIULIANA S.; MENDES, ERICA A.; LADNER, JASON T.; ANDREATA-SANTOS, ROBERT; ARAUJO, DANIELLE B.; BOTOSSO, VIVIANE F.; PAOLA, NICHOLAS D.; NETO, DANIEL F. L.; CUNHA, MARIELTON P.; et al. Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System. Viruses-Basel, v. 10, n. 11, . (13/07467-1, 14/17766-9, 14/27228-4, 14/16333-1, 16/08727-5, 15/25643-7, 14/03911-7, 16/08204-2, 16/20045-7, 13/26942-2, 16/03605-9)
PACHECO, MARIO T. F.; MORAIS, KATIA L. P.; BERRA, CAROLINA M.; DEMASI, MARILENE; SCIANI, JULIANA M.; BRANCO, VANIA G.; BOSCH, ROSEMARY V.; IQBAL, ASIF; CHUDZINSKI-TAVASSI, ANA MARISA. Specific role of cytoplasmic dynein in the mechanism of action of an antitumor molecule, Amblyomin-X. Experimental Cell Research, v. 340, n. 2, p. 248-258, . (10/07958-7, 13/07467-1, 00/11624-5, 11/05969-4)
CALDERANO, SIMONE GUEDES; DROSOPOULOS, WILLIAM C.; QUARESMA, MARINA MONACO; MARQUES, CATARINA A.; KOSIYATRAKUL, SETTAPONG; MCCULLOCH, RICHARD; SCHILDKRAUT, CARL L.; ELIAS, MARIA CAROLINA. Single molecule analysis of Trypanosoma brucei DNA replication dynamics. Nucleic Acids Research, v. 43, n. 5, p. 2655-2665, . (13/07467-1, 08/56414-0, 11/21570-4, 12/24554-2)
DIAS, MATHEUS H.; KITANO, EDUARDO S.; ZELANIS, ANDRE; IWAI, LEO K.. Proteomics and drug discovery in cancer. DRUG DISCOVERY TODAY, v. 21, n. 2, p. 264-277, . (12/20186-9, 11/11308-0, 14/06579-3, 13/07467-1)
SILVA, JULIETE A. F.; BIANCARDI, MANOEL F.; STACH-MACHADO, DAGMAR R.; REIS, LEONARDO O.; SANT'ANNA, OSVALDO A.; CARVALHO, HERNANDES F.. The origin of prostate gland-secreted IgA and IgG. SCIENTIFIC REPORTS, v. 7, . (13/07467-1, 09/16150-6)
DE FARIAS, IASMIM BAPTISTA; DE MORAIS-ZANI, KAREN; SERINO-SILVA, CAROLINE; SANT'ANNA, SAVIO S.; DA ROCHA, MARISA M. T.; GREGO, KATHLEEN F.; ANDRADE-SILVA, DEBORA; SERRANO, SOLANGE M. T.; TANAKA-AZEVEDO, ANITA M.. Functional and proteomic comparison of Bothrops jararaca venom from captive specimens and the Brazilian Bothropic Reference Venom. JOURNAL OF PROTEOMICS, v. 174, p. 36-46, . (13/07467-1, 16/16935-7, 14/11108-0, 17/01890-0, 17/16908-2, 13/05357-4)
DIAZ-ROA, ANDREA; PATARROYO, MANUEL A.; BELLO, FELIO J.; DA SILVA, JR., PEDRO I.. Sarconesin: Sarconesiopsis magellanica Blowfly Larval Excretions and Secretions With Antibacterial Properties. FRONTIERS IN MICROBIOLOGY, v. 9, . (13/07467-1)
REIS, MARCELO S.; ESTRELA, GUSTAVO; FERREIRA, CARLOS EDUARDO; BARRERA, JUNIOR. Optimal Boolean lattice-based algorithms for the U-curve optimization problem. INFORMATION SCIENCES, v. 471, p. 97-114, . (13/07467-1, 11/50761-2, 14/23564-0)
TORRES-BONILLA, KRISTIAN A.; ANDRADE-SILVA, DEBORA; SERRANO, SOLANGE M. T.; HYSLOP, STEPHEN. Biochemical characterization of venom from Pseudoboa neuwiedii (Neuwied's false boa; Xenodontinae; Pseudoboini). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, v. 213, p. 27-38, . (13/07467-1)
DA SILVA, MARCELO S.; CAYRES-SILVA, GUSTAVO R.; VITARELLI, MARCELA O.; MARIN, PAULA A.; HIRAIWA, PRISCILA M.; ARAUJO, CHRISTIANE B.; SCHOLL, BRUNO B.; AVILA, ANDREA R.; MCCULLOCH, RICHARD; REIS, MARCELO S.; et al. Transcription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase duration. SCIENTIFIC REPORTS, v. 9, . (15/10580-0, 17/07693-2, 17/18719-2, 16/17775-3, 14/24170-5, 16/50050-2, 13/07467-1, 14/13375-5)
BRESSAN, ELISANGELA; TOUSKA, FILIP; VETTER, IRINA; KISTNER, KATRIN; KICHKO, TATJANA I.; TEIXEIRA, NATHALIA B.; PICOLO, GISELE; CURY, YARA; LEWIS, RICHARD J.; FISCHER, MICHAEL J. M.; et al. Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia. Pain, v. 157, n. 11, p. 2504-2516, . (08/57898-0, 12/51458-4, 13/07467-1, 98/14307-9)
DE ARAUJO, CHRISTIANE BEZERRA; DE LIMA, LOYZE PAOLA; CALDERANO, SIMONE GUEDES; DAMASCENO, FLAVIA SILVA; SILBER, ARIEL M.; ELIAS, MARIA CAROLINA. Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the Trypanosoma cruzi Life Cycle and Blocks Parasite Infectivity. Antimicrobial Agents and Chemotherapy, v. 63, n. 5, . (13/07467-1, 16/06034-2, 17/16553-0, 16/50050-2, 14/13375-5)
MORAIS, KATIA L. P.; FERNANDES PACHECO, MARIO THIEGO; BERRA, CAROLINA MARIA; BOSCH, ROSEMARY V.; SCIANI, JULIANA MOZER; CHAMMAS, ROGER; SAITO, RENATA DE FREITAS; IQBAL, ASIF; CHUDZINSKI-TAVASSI, ANA MARISA. Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell. Molecular and Cellular Biochemistry, v. 415, n. 1-2, p. 119-131, . (13/07467-1, 10/52669-3, 11/05969-4, 98/14307-9, 10/07958-7)
DE ARAUJO, CHRISTIANE BEZERRA; CHAGAS DA CUNHA, JULIA PINHEIRO; INADA, DAVI TOSHIO; DAMASCENO, JEZIEL; JERONIMO LIMA, ALEX RANIERI; HIRAIWA, PRISCILA; MARQUES, CATARINA; GONCALVES, EVONNILDO; NISHIYAMA-JUNIOR, MILTON YUTAKA; MCCULLOCH, RICHARD; et al. Replication origin location might contribute to genetic variability in Trypanosoma cruzi. BMC Genomics, v. 21, n. 1, . (13/07467-1, 14/24170-5, 16/50050-2, 14/13375-5)
DA SILVA, MARCELO S.; VITARELLI, MARCELA O.; SOUZA, BRUNO F.; ELIAS, MARIA CAROLINA. Comparative Analysis of the Minimum Number of Replication Origins in Trypanosomatids and Yeasts. GENES, v. 11, n. 5, . (13/07467-1, 14/24170-5, 16/50050-2, 17/18719-2, 17/07693-2)
MOURA-DA-SILVA, ANA MARIA; CONTRERAS-BERNAL, JORGE CARLOS; GIMENES, SARAH NATALIE CIRILO; FREITAS-DE-SOUSA, LUCIANA APARECIDA; PORTES-JUNIOR, JOSE ANTONIO; PEIXOTO, PEDRO DA SILVA; IWAI, LEO KEI; DE MOURA, VALERIA MOURAO; BISNETO, PEDRO FERREIRA; LACERDA, MARCUS; et al. The relationship between clinics and the venom of the causative Amazon pit viper (Bothrops atrox). PLoS Neglected Tropical Diseases, v. 14, n. 6, . (13/07467-1, 18/13108-8, 18/25749-8, 17/24546-3)
LOPES, PRISCILA HESS; MURAKAMI, MARIO T.; PORTARO, V, FERNANDA C.; MESQUITA PASQUALOTO, KERLY FERNANDA; VAN DEN BERG, CARMEN; TAMBOURGI, V, DENISE. Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. Journal of Enzyme Inhibition and Medicinal Chemistry, v. 34, n. 1, p. 310-321, . (13/07467-1, 08/57898-0, 15/17053-5)
LIBERATO, TARCISIO; FUKUSHIMA, ISABELLA; KITANO, EDUARDO S.; SERRANO, SOLANGE M. T.; CHAMMAS, ROGER; ZELANIS, ANDRE. Proteomic profiling of the proteolytic events in the secretome of the transformed phenotype of melanocyte-derived cells using Terminal Amine Isotopic Labeling of Substrates. JOURNAL OF PROTEOMICS, v. 192, p. 291-298, . (14/06579-3, 15/18096-0, 13/07467-1, 17/07897-7)
OKAMOTO, CINTHYA KIMORI; VAN DEN BERG, CARMEN W.; MASASHI, MIZUNO; GONCALVES-DE-ANDRADE, RUTE M.; TAMBOURGI, DENISE V.. Tetracycline Reduces Kidney Damage Induced by Loxosceles Spider Venom. TOXINS, v. 9, n. 3, . (13/07467-1)
REIS, MARCELO S.; ESTRELA, GUSTAVO; FERREIRA, CARLOS EDUARDO; BARRERA, JUNIOR. featsel: A framework for benchmarking of feature selection algorithms and cost functions. SOFTWAREX, v. 6, p. 193-197, . (13/03447-6, 15/01587-0, 16/25959-7, 13/07467-1)
MENEZES, MILENE C.; KITANO, EDUARDO S.; BAUER, VERENA C.; OLIVEIRA, ANA K.; CARARO-LOPES, EDUARDO; NISHIYAMA, JR., MILTON Y.; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.. Early response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom. JOURNAL OF PROTEOMICS, v. 198, p. 163-176, . (13/07467-1, 15/23691-4, 11/11308-0)
ANDRADE-SILVA, DEBORA; ASHLINE, DAVID; TRAN, THUY; LOPES, ALINE SORIANO; TRAVAGLIA CARDOSO, SILVIA REGINA; REIS, MARCELO DA SILVA; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.; REINHOLD, VERNON. Structures of N-Glycans of Bothrops Venoms Revealed as Molecular Signatures that Contribute to Venom Phenotype in Viperid Snakes. MOLECULAR & CELLULAR PROTEOMICS, v. 17, n. 7, p. 1261-1284, . (13/07467-1, 14/12245-0, 13/14651-3, 13/13548-4)
DA SILVA, MARCELO S.; MARINI, PAULA A.; REPOLES, BRUNO M.; ELIAS, MARIA C.; MACHADO, CARLOS R.. Analysis of DNA Exchange Using Thymidine Analogs (ADExTA) in Trypanosoma cruzi. BIO-PROTOCOL, v. 8, n. 24, . (13/07467-1, 14/24170-5, 17/18719-2)
MENEGUELLO, LETICIA; BARBOSA, NATALIA M.; PEREIRA, KARINA D.; PROENCA, ANDRE R. G.; TAMBORLIN, LETICIA; SIMABUCO, FERNANDO M.; IWAI, LEO K.; ZANELLI, CLESLEI F.; VALENTINI, SANDRO R.; LUCHESSI, AUGUSTO D.. The polyproline-motif of S6K2: eIF5A translational dependence and importance for protein-protein interactions. Journal of Cellular Biochemistry, v. 120, n. 4, p. 6015-6025, . (13/07467-1, 12/13558-7, 10/18095-0)
FERNANDES SILVA, CRISTIANE CASTILHO; MENEZES, MILENE CRISTINA; PALOMINO, MIRYAM; OLIVEIRA, ANA KARINA; IWAI, LEO KEI; FARIA, MARCELLA; PORTARO, FERNANDA VIEIRA. Peptides derived from plasma proteins released by bothropasin, a metalloprotease present in the Bothrops jararaca venom. Toxicon, v. 137, p. 65-72, . (14/02788-7, 13/07467-1, 15/15364-3)
KUNIYOSHI, ALEXANDRE KAZUO; KODAMA, ROBERTO TADASHI; FERREIRA MORAES, LUIS HENRIQUE; DUZZI, BRUNO; IWAI, LEO KEI; LIMA, ISMAEL FEITOSA; CAJADO-CARVALHO, DANIELA; PORTARO, FERNANDA VIEIRA. In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases. Toxicon, v. 137, p. 114-119, . (13/07467-1, 15/13124-5, 12/06677-0, 15/15364-3, 13/15344-7)
DINIZ, V, MARCELO R.; PAIVA, ANA L. B.; GUERRA-DUARTE, CLARA; NISHIYAMA JR, MILTON Y.; MUDADU, MAURICIO A.; DE OLIVEIRA, URSULA; BORGES, MARCIA H.; YATES, JOHN R.; JUNQUEIRA-DE-AZEVEDO, INACIO DE L.. An overview of Phoneutria nigriventer spider venom using combined transcriptomic and proteomic approaches. PLoS One, v. 13, n. 8, . (13/07467-1)
FREITAS-DE-SOUSA, L. A.; AMAZONAS, D. R.; SOUSA, L. F.; SANT'ANNA, S. S.; NISHIYAMA, JR., M. Y.; SERRANO, S. M. T.; JUNQUEIRA-DE-AZEVEDO, I. L. M.; CHALKIDIS, H. M.; MOURA-DA-SILVA, A. M.; MOURAO, R. H. V.. Comparison of venoms from wild and long-term captive Bothrops atrox snakes and characterization of Batroxrhagin, the predominant class PIII metalloproteinase from the venom of this species. Biochimie, v. 118, p. 60-70, . (13/07467-1, 12/16277-9, 14/26058-8)
CANDIDO-FERREIRA, IVAN LAVANDER; KRONENBERGER, THALES; ROSA SAYEGH, RAPHAEL SANTA; CORREIA BATISTA, ISABEL DE FATIMA; DA SILVA JUNIOR, PEDRO ISMAEL. Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases. FRONTIERS IN IMMUNOLOGY, v. 7, . (14/03644-9, 13/07467-1)
ZELANIS, ANDRE; OLIVEIRA, ANA K.; PRUDOVA, ANNA; HUESGEN, PITTER F.; TASHIMA, ALEXANDRE K.; KIZHAKKEDATHU, JAYACHANDRAN; OVERALL, CHRISTOPHER M.; SERRANO, SOLANGE M. T.. Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Substrates (TAILS) N-Terminomics. JOURNAL OF PROTEOME RESEARCH, v. 18, n. 9, p. 3419-3428, . (13/07467-1, 11/23403-8, 11/08514-8, 10/17328-0)
OLIVEIRA, THIAGO DE JESUS; DE OLIVEIRA, URSULA CASTRO; DA SILVA JUNIOR, PEDRO ISMAEL. Serrulin: A Glycine-Rich Bioactive Peptide from the Hemolymph of the Yellow Tityus serrulatus Scorpion. TOXINS, v. 11, n. 9, . (13/07467-1)
YAMASHIRO, EDSON T.; OLIVEIRA, ANA K.; KITANO, EDUARDO S.; MENEZES, MILENE C.; JUNQUEIRA-DE-AZEVEDO, INACIO L.; LEME, ADRIANA F. PAES; SERRANO, SOLANGE M. T.. Proteoforms of the platelet-aggregating enzyme PA-BJ, a serine proteinase from Bothrops jararaca venom. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1844, n. 12, p. 2068-2076, . (13/07467-1, 11/11308-0, 11/08514-8, 98/14307-9)
SERRANO, SOLANGE M. T.; OLIVEIRA, ANA K.; MENEZES, MILENE C.; ZELANIS, ANDRE. The proteinase-rich proteome of Bothrops jararaca venom. Toxin Reviews, v. 33, n. 4, p. 169-184, . (13/07467-1, 10/17328-0)
DREWES, C. C.; DIAS, R. Y.; BRANCO, V. G.; CAVALCANTE, M. F.; SOUZA, J. G.; ABDALLA, D. S. P.; CHUDZINSKI-TAVASSI, A. M.; FARSKY, S. H. P.. Post-transcriptional control of Amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endothelial cells. Toxicon, v. 101, p. 1-10, . (09/08584-6, 13/07467-1, 08/56072-1, 08/57850-8, 12/06944-8, 10/19802-1)
LEANDRO DE JESUS, TERESA CRISTINA; NUNES, VINICIUS SANTANA; LOPES, MARIANA DE CAMARGO; MARTIL, DAIANA EVELIN; IWAI, LEO KEI; MORETTI, NILMAR SILVIO; MACHADO, FABRICIO CASTRO; DE LIMA-STEIN, MARIANA L.; THIEMANN, OTAVIO HENRIQUE; ELIAS, MARIA CAROLINA; et al. Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi. JOURNAL OF PROTEOME RESEARCH, v. 15, n. 6, p. 2039-2051, . (13/07467-1, 14/03714-7, 08/57910-0, 12/09403-8, 15/04867-4, 11/06087-5, 11/51973-3, 11/22619-7, 14/01577-2)
LOPES-FERREIRA, MONICA; SOSA-ROSALES, INES; BRUNI, FERNANDA M.; RAMOS, ANDERSON D.; VIEIRA PORTARO, FERNANDA CALHETA; CONCEICAO, KATIA; LIMA, CARLA. Analysis of the intersexual variation in Thalassophryne maculosa fish venoms. Toxicon, v. 115, p. 70-80, . (13/07467-1)
BERTHOLIM, LUCIANA; ZELANIS, ANDRE; OLIVEIRA, ANA K.; SERRANO, SOLANGE M. T.. Proteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase. Amino Acids, v. 48, n. 5, p. 1331-1335, . (13/07467-1, 11/16623-1)
ZELANIS, ANDRE; MENEZES, MILENE C.; KITANO, EDUARDO S.; LIBERATO, TARCISIO; TASHIMA, ALEXANDRE K.; PINTO, ANTONIO F. M.; SHERMAN, NICHOLAS E.; HO, PAULO L.; FOX, JAY W.; SERRANO, SOLANGE M. T.. Proteomic identification of gender molecular markers in Bothrops jararaca venom. JOURNAL OF PROTEOMICS, v. 139, p. 26-37, . (13/07467-1, 07/54626-7, 06/60486-0, 13/13548-4, 98/14307-9)
BUENO, VALQUIRIA; SANT'ANNA, OSVALDO AUGUSTO; LORD, JANET M.. Ageing and myeloid-derived suppressor cells: possible involvement in immunosenescence and age-related disease. AGE, v. 36, n. 6, . (13/07467-1, 12/51747-6)
MANZONI-DE-ALMEIDA, DANIEL; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; LOPES, PRISCILA HESS; VAN DEN BERG, CARMEN W.; TAMBOURGI, DENISE V.. Loxosceles venom Sphingomyelinase D activates human blood leukocytes: Role of the complement system. Molecular Immunology, v. 94, p. 45-53, . (13/07467-1, 15/17053-5)
PARIONA-LLANOS, RICARDO; PAVANI, RAPHAEL SOUZA; REIS, MARCELO; NOEL, VINCENT; SILBER, ARIEL MARIANO; ARMELIN, HUGO AGUIRRE; CANO, MARIA ISABEL NOGUEIRA; ELIAS, MARIA CAROLINA. Glyceraldehyde 3-Phosphate Dehydrogenase-Telomere Association Correlates with Redox Status in Trypanosoma cruzi. PLoS One, v. 10, n. 3, . (13/07467-1, 11/50631-1, 05/00154-1)
JUNQUEIRA-DE-AZEVEDO, INACIO L. M.; VAL BASTOS, CAROLINA MANCINI; HO, PAULO LEE; LUNA, MILENE SCHMIDT; YAMANOUYE, NORMA; CASEWELL, NICHOLAS R.. Venom-Related Transcripts from Bothrops jararaca Tissues Provide Novel Molecular Insights into the Production and Evolution of Snake Venom. Molecular Biology and Evolution, v. 32, n. 3, p. 754-766, . (13/07467-1, 12/00177-5)
CEOLIN MARIANO, DOUGLAS OSCAR; MESSIAS, MARCELA DI GIACOMO; SPENCER, PATRICK JACK; PIMENTA, DANIEL CARVALHO. Protein identification from the parotoid macrogland secretion of Duttaphrynus melanostictus. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 25, . (13/07467-1)
CEOLIN MARIANO, DOUGLAS OSCAR; DE OLIVEIRA, URSULA CASTRO; ZAHARENKO, ANDRE JUNQUEIRA; PIMENTA, DANIEL CARVALHO; RADIS-BAPTISTA, GANDHI; DE BRANDAO PRIETO-DA-SILVA, ALVARO ROSSAN. Bottom-Up Proteomic Analysis of Polypeptide Venom Components of the Giant Ant Dinoponera Quadriceps. TOXINS, v. 11, n. 8, . (13/07467-1)
TANAKA, GABRIELA D.; SANT'ANNA, OSVALDO AUGUSTO; MARCELINO, JOSE ROBERTO; LUSTOZA DA LUZ, ANA CRISTINA; TEIXEIRA DA ROCHA, MARISA MARIA; TAMBOURGI, DENISE V.. Micrurus snake species: Venom immunogenicity, antiserum cross-reactivity and neutralization potential. Toxicon, v. 117, p. 59-68, . (13/07467-1)
SILVA-DE-FRANCA, FELIPE; VILLAS-BOAS, ISADORA MARIA; DE TOLEDO SERRANO, SOLANGE MARIA; COGLIATI, BRUNO; DE ANDRADE CHUDZINSKI, SONIA APARECIDA; LOPES, PRISCILA HESS; KITANO, EDUARDO SHIGUEO; OKAMOTO, CINTHYA KIMORI; TAMBOURGI, DENISE V.. Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation. PLoS Neglected Tropical Diseases, v. 13, n. 1, . (13/07467-1)
SILVA, NORTON FELIPE DOS SANTOS; WILLEMART, RODRIGO HIRATA; DA SILVA, JOSE ROBERTO MACHADO CUNHA; DA SILVA JUNIOR, PEDRO ISMAEL. rotein Components of the Arthrodial Membrane Gland in a Neotropical Harvestman (Arachnida, Opiliones. ACS OMEGA, . (13/07467-1, 20/05158-5)
CAETANO, LHIRI HANNA DE LUCCA; NISHIYAMA-JR, MILTON YUTAKA; TAVORA, BIANCA DE CARVALHO LINS FERNANDES; DE OLIVEIRA, URSULA CASTRO; JUNQUEIRA-DE-AZEVEDO, INACIO DE LOIOLA MEIRELLES; FAQUIM-MAURO, ELIANA L.; MAGALHAES, GERALDO SANTANA. Recombinant Production and Characterization of a New Toxin from Cryptops iheringi Centipede Venom Revealed by Proteome and Transcriptome Analysis. TOXINS, v. 13, n. 12, . (17/13812-4, 17/16999-8, 13/07467-1)
BOTOSSO, VIVIANE FONGARO; CALIL JORGE, SORAIA ATTIE; ASTRAY, RENATO MANCINI; DE SA GUIMARAES, ANA MARCIA; MATHOR, MONICA BEATRIZ; DE CARNEIRO, PATRICIA DOS SANTOS; DURIGON, EDISON LUIZ; COVAS, DIMAS; LEAL DE OLIVEIRA, DANIELLE BRUNA; OLIVEIRA, RICARDO DAS NEVES; et al. Anti-SARS-CoV-2 equine F (Ab ')(2) immunoglobulin as a possible therapy for COVID-19. SCIENTIFIC REPORTS, v. 12, n. 1, p. 17-pg., . (13/26450-2, 14/11513-1, 20/07251-2, 20/09149-0, 13/07467-1, 18/04609-3, 19/27348-3, 20/05293-0, 19/12303-4)
DISNER, GEONILDO RODRIGO; LOPES-FERREIRA, MONICA; LIMA, CARLA. Where the Aryl Hydrocarbon Receptor Meets the microRNAs: Literature Review of the Last 10 Years. FRONTIERS IN MOLECULAR BIOSCIENCES, v. 8, p. 13-pg., . (19/27677-7, 13/07467-1)
LIMA, CARLA; MALESKI, ADOLFO LUIS ALMEIDA; BERNARDO, JEFFERSON THIAGO GONCALVES; ZELLI, VITOR CATALDI; KOMEGAE, EVILIN NANAME; LOPES-FERREIRA, MONICA. TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model. FRONTIERS IN IMMUNOLOGY, v. 13, p. 13-pg., . (13/07467-1)
GIARDINI, ALINE C.; EVANGELISTA, BIANCA G.; SANT'ANNA, MORENA B.; MARTINS, BARBARA B.; LANCELLOTTI, CARMEN L. P.; CIENA, ADRIANO P.; CHACUR, MARUCIA; PAGANO, ROSANA L.; RIBEIRO, ORLANDO G.; ZAMBELLI, VANESSA O.; et al. Crotalphine Attenuates Pain and Neuroinflammation Induced by Experimental Autoimmune Encephalomyelitis in Mice. TOXINS, v. 13, n. 11, p. 19-pg., . (15/01254-1, 13/07467-1)
ALMEIDA, DIEGO DANTAS; VIALA, VINCENT LOUIS; NACHTIGALL, PEDRO GABRIEL; BROE, MICHAEL; GIBBS, H. LISLE; SERRANO, SOLANGE MARIA DE TOLEDO; MOURA-DA-SILVA, ANA MARIA; HO, PAULO LEE; NISHIYAMA-JR, MILTON YUTAKA; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca genome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 118, n. 20, . (16/50127-5, 13/07467-1, 15/03509-7, 12/00177-5, 18/26520-4)
COSTA-SILVA, HELLIDA MARINA; RESENDE, BRUNO CARVALHO; UMAKI, ADRIANA CASTILHOS SOUZA; PRADO, WILLIAN; DA SILVA, MARCELO SANTOS; VIRGILIO, STELA; MACEDO, ANDREA MARA; PENA, SERGIO DANILO JUNHO; TAHARA, ERICH BIRELLI; TOSI, LUIZ RICARDO ORSINI; et al. DNA Topoisomerase 3 alpha Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, v. 9, . (14/24170-5, 18/14398-0, 13/07467-1, 16/50050-2)
HENRIQUE, CAMILA; PIMENTEL FALCAO, MARIA ALICE; PIMENTA, LUCIANA DE ARAUJO; ALMEIDA MALESKI, ADOLFO LUIS; LIMA, CARLA; MITSUNARI, THAIS; SAMPAIO, SANDRA COCCUZZO; LOPES-FERREIRA, MONICA; FONTES PIAZZA, ROXANE MARIA. Heat-Labile Toxin from Enterotoxigenic Escherichia coli Causes Systemic Impairment in Zebrafish Model. TOXINS, v. 13, n. 6, . (13/07467-1, 17/17213-8)
ALMEIDA, TAMIRES CUNHA; SILVA, LORENA DE MORAIS RIBEIRO; DE OLIVEIRA, ANA MARIA BOAVENTURA; LOPES, FLAVIA SOUZA RIBEIRO; SANT'ANNA, MORENA BRAZIL; PICOLO, GISELE. Cytotoxic effect of crotoxin on cancer cells and its antitumoral effects correlated to tumor microenvironment: A review. International Journal of Biological Macromolecules, v. 242, p. 8-pg., . (13/07467-1, 21/10344-5, 19/17109-1)
SILVA, MARCELO S. DA; VITARELLI, MARCELA O.; VIALA, VINCENT LOUIS; TSANTARLIS, KATHERINE; PIRES, DAVID DA SILVA; FRANCO, THIAGO A.; DE AZEVEDO, INACIO L. M. J.; ELIAS, MARIA CAROLINA; TONELLI, RENATA R.. Clues on the dynamics of DNA replication in Giardia lamblia. Journal of Cell Science, v. 136, n. 10, p. 13-pg., . (17/07693-2, 20/10277-3, 18/14432-3, 13/07467-1, 14/24170-5, 19/02918-1, 20/00694-6, 16/50050-2, 19/10753-2)
ESPINOZA-CULUPU, ABRAHAM; VAZQUEZ-RAMIREZ, RICARDO; FARFAN-LOPEZ, MARIELLA; MENDES, ELIZABETH; NOTOMI SATO, MARIA; DA SILVA JUNIOR, PEDRO ISMAEL; BORGES, MONAMARIS MARQUES. Acylpolyamine Mygalin as a TLR4 Antagonist Based on Molecular Docking and In Vitro Analyses. BIOMOLECULES, v. 10, n. 12, . (13/11212-9, 13/07467-1)
SILVA DE FRANCA, FELIPE; GABRILI, JOEL JOSE MEGALE; MATHIEU, LAURENCE; BURGHER, FRANCOIS; BLOMET, JOEL; TAMBOURGI, DENISE V.. Bothrops lanceolatus snake (Fer-de-lance) venom triggers inflammatory mediators' storm in human blood. ARCHIVES OF TOXICOLOGY, . (13/07467-1)
SANTOS, W. S.; MONTONI, FABIO; EICHLER, R. A. S.; SUEHIRO ARCOS, STEPHANIE SANTOS; ANDREOTTI, DIANA ZUKAS; KISAKI, CAROLINA YUKIKO; EVANGELISTA, KIMBERLY BORGES; CALACINA, HAMIDA MACEDO; LIMA, ISMAEL FEITOSA; MALTAURO SOARES, MAGNA APARECIDA; et al. Proteomic analysis reveals rattlesnake venom modulation of proteins associated with cardiac tissue damage in mouse hearts. JOURNAL OF PROTEOMICS, v. 258, p. 12-pg., . (17/06496-9, 13/07467-1, 17/17943-6, 16/04000-3)
BUENO, THAIS CAVENATTI; COLLACO, RITA DE CASSIA; CARDOSO, BIANCA APARECIDA; BREDARIOL, RAFAEL FUMACHI; ESCOBAR, MARILIA LEAL; CAJADO, ISABELA BUBENIK; GRACIA, MARTA; ANTUNES, EDSON; ZAMBELLI, VANESSA O.; PICOLO, GISELE; et al. Neurotoxicity of Olindias sambaquiensis and Chiropsalmus quadrumanus extracts in sympathetic nervous system. Toxicon, v. 199, p. 127-138, . (11/50242-5, 13/07467-1)
DISNER, GEONILDO R.; FALCAO, MARIA A. P.; LIMA, CARLA; LOPES-FERREIRA, MONICA. In Silico Target Prediction of Overexpressed microRNAs from LPS-Challenged Zebrafish (Danio rerio) Treated with the Novel Anti-Inflammatory Peptide TnP. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 22, n. 13, . (13/07467-1, 19/27677-7)
AOUNALLAH, HAJER; BENSAOUD, CHAIMA; M'GHIRBI, YOUMNA; FARIA, FERNANDA; CHMELAR, JINDRICH; KOTSYFAKIS, MICHAIL. Tick Salivary Compounds for Targeted Immunomodulatory Therapy. FRONTIERS IN IMMUNOLOGY, v. 11, . (13/07467-1)
LOPES-FERREIRA, MONICA; SOSA-ROSALES, INES; SILVA JUNIOR, PEDRO ISMAEL; CONCEICAO, KATIA; MALESKI, ADOLFO LUIS ALMEIDA; BALAN-LIMA, LETICIA; DISNER, GEONILDO RODRIGO; LIMA, CARLA. olecular Characterization and Functional Analysis of the Nattectin-like Toxin from the Venomous Fish Thalassophryne maculos. OXIN, v. 14, n. 1, . (13/07467-1)
ROSON, JULIANA NUNES; VITARELLI, MARCELA DE OLIVEIRA J.; COSTA-SILVA, HELLIDA MARINA; PEREIRA, KAMILLE SCHMITT; PIRES, DAVID DA SILVA; LOPES, LETICIA DE SOUSA; CORDEIRO, BARBARA; KRAUS, AMELIE; CRUZ, KARIN NAVARRO TOZZI; CALDERANO, SIMONE GUEDES; et al. 2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasio. PLOS PATHOGENS, v. 18, n. 2, . (18/15553-9, 16/50050-2, 17/06104-3, 19/04483-2, 19/16033-1, 13/07467-1, 19/19834-5)
FERNANDES, DAYANNE CARLA; TAMBOURGI, DENISE V.. Complement System Inhibitory Drugs in a Zebrafish (Danio rerio) Model: Computational Modeling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 18, p. 20-pg., . (13/07467-1, 19/27348-3)
MORAIS, K. L. P.; CICCONE, L.; STURA, E.; ALVAREZ-FLORES, M. P.; MOURIER, G.; DRIESSCHE, M. VANDEN; SCIANI, J. M.; IQBAL, A.; KALIL, S. P.; PEREIRA, G. J.; et al. Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity. FRONTIERS IN MOLECULAR BIOSCIENCES, v. 10, p. 16-pg., . (15/50040-4, 20/13139-0, 13/07467-1)
GALLO, GLORIA; BARCICK, UILLA; COELHO, CAMILA; SALARDANI, MURILO; CAMACHO, MAURICIO F.; CAJADO-CARVALHO, DANIELA; LOURES, FLAVIO V.; SERRANO, SOLANGE M. T.; HARDY, LEON; ZELANIS, ANDRE; et al. A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity. Peptides, v. 154, p. 8-pg., . (11/50963-4, 13/07467-1, 19/07282-8)
LEONEL, THYAGO BISPO; GABRILI, JOEL JOSE MEGALE; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; WOODRUFF, TRENT M.; LAMBRIS, JOHN D.; TAMBOURGI, DENISE V.. Bothrops jararaca Snake Venom Inflammation Induced in Human Whole Blood: Role of the Complement System. FRONTIERS IN IMMUNOLOGY, v. 13, p. 16-pg., . (13/07467-1)
BARRERA, JUNIOR; HASHIMOTO, RONALDO F.; HIRATA, NINA S. T.; HIRATA, R., JR.; REIS, MARCELO S.. From Mathematical Morphology to machine learning of image operators. SAO PAULO JOURNAL OF MATHEMATICAL SCIENCES, v. 16, n. 1, p. 42-pg., . (15/22308-2, 13/07467-1, 19/21619-5, 17/25835-9)
HAYASHIDA, PATRICIA YUMI; DA SILVA JUNIOR, PEDRO ISMAEL. Insights into Antimicrobial Peptides from Limacus flavus Mucus. Current Microbiology, v. 78, n. 8, p. 2970-2979, . (13/07467-1)
PAVANI, RAPHAEL S.; DE LIMA, LOYZE P.; LIMA, ANDRE A.; FERNANDES, CARLOS A. H.; FRAGOSO, STENIO P.; CALDERANO, SIMONE G.; ELIAS, MARIA CAROLINA. Nuclear export of replication protein A in the nonreplicative infective forms of Trypanosoma cruzi. FEBS Letters, v. 594, n. 10, p. 1596-1607, . (16/50050-2, 14/02978-0, 18/14432-3, 18/21785-0, 13/07467-1)
ELIAS, MARIA CAROLINA; SLAVOV, SVETOSLAV NANEV; LIMA, ALEX RANIERI JERONIMO; MARTINS, ANTONIO JORGE; BARROS, CLAUDIA RENATA DOS SANTOS; MORETTI, DEBORA BOTEQUIO; ARAUJO, EDUARDO L.; MARQUEZE, ELAINE CRISTINA; RIBEIRO, GABRIELA; RIBEIRO, GABRIELA MAURIC FROSSARD; et al. A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations. BMC PUBLIC HEALTH, v. 23, n. 1, p. 9-pg., . (20/10127-1, 20/00694-6, 18/15826-5, 13/07467-1)
FERREIRA, MONICA LOPES; FALCAO, MARIA ALICE PIMENTEL; BRUNI, FERNANDA MIRIANE; HADDAD JR, VIDAL; MARQUES, ELINEIDE EUGENIO; SEIBERT, CARLA SIMONE; LIMA, CARLA. Effective Pre-Clinical Treatment of Fish Envenoming with Polyclonal Antiserum. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 9, p. 18-pg., . (13/07467-1, 05/58101-0)
MONTONI, FABIO; DE SOUSA, RONALDO N.; DE LIMA JUNIOR, MARCELO B.; CAMPOS, CRISTIANO G. S.; WANG, WILLIAN; CONSTANTINO, VIVIAN M.; SANCTOS, CASSIA S.; ARMELIN, HUGO A.; REIS, MARCELO S.; IEEE. Anguix: Cell Signaling Modeling Improvement through Sabio-RK association to Reactome. 2022 IEEE 18TH INTERNATIONAL CONFERENCE ON E-SCIENCE (ESCIENCE 2022), v. N/A, p. 2-pg., . (20/08555-5, 13/07467-1, 21/04355-4, 20/10329-3, 19/24580-2, 19/21619-5)
BURI, MARCUS VINICIUS; GARAVELLI, GRACIANA YOKOTA; VIGERELLI, HUGO; DE SOUZA, MARCELO MEDINA; MAIA LOBBA, ALINE RAMOS; GHIDELLI-DISSE, SONJA; CHUDZINSKI-TAVASSI, ANA MARISA. cAmbly: A non-toxic cell-penetrating peptide derived from Amblyomin-X with targeted delivery to mitochondrial and cytoplasmic proteins. PLoS One, v. 20, n. 3, p. 14-pg., . (15/50040-4, 20/13139-0, 13/07467-1)
LIMA, GUILHERME M.; MENEZES, MILENE C.; COSTA, IRIS M.; SERRANO, SOLANGE M. T.; MONTEIRO, GISELE. Development of a cell-free protein synthesis protocol to rapidly screen L-asparaginase proteoforms by enzymatic activity. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, v. 96, n. 9, p. 2659-2666, . (18/15041-8, 13/08617-7, 13/07467-1, 18/15104-0, 16/25896-5)
LONGHI, M. T.; SILVA, L. E.; PEREIRA, M.; MAGALHAES, M.; REINA, J.; VITORINO, F. N. L.; GUMBINER, B. M.; DA CUNHA, J. P. C.; CELLA, N.. PI3K-AKT, JAK2-STAT3 pathways and cell-cell contact regulate maspin subcellular localization. CELL COMMUNICATION AND SIGNALING, v. 19, n. 1, . (17/18344-9, 13/00815-4, 15/09309-0, 13/07467-1, 15/16384-8)
KATO, ELLEN EMI; PIMENTA, LUCIANA ARAUJO; SOARES DE ALMEIDA, MAIRA ESTANISLAU; ZAMBELLI, VANESSA OLZON; DOS SANTOS, MARINILCE FAGUNDES; SAMPAIO, SANDRA COCCUZZO. rotoxin Inhibits Endothelial Cell Functions in Two- and Three-dimensional Tumor Microenvironmen. FRONTIERS IN PHARMACOLOGY, v. 12, . (13/07467-1, 12/51241-5)
KISAKI, CAROLINA YUKIKO; ARCOS, STEPHANIE SANTOS SUEHIRO; MONTONI, FABIO; DA SILVA SANTOS, WELLINGTON; CALACINA, HAMIDA MACEDO; LIMA, ISMAEL FEITOSA; CAJADO-CARVALHO, DANIELA; FERRO, EMER SUAVINHO; NISHIYAMA-JR, MILTON YUTAKA; IWAI, LEO KEI. Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines. TOXINS, v. 13, n. 8, . (17/06496-9, 13/07467-1, 16/04000-3, 17/17943-6)
KIMURA, LOUISE F.; SANT'ANNA, MORENA B.; ANDRADE, SONIA A.; EBRAM, MATTEO C.; LIMA, CRISTIANE F. G.; CELANO, ROSA M. G.; VIEGAS, RUY F. M.; PICOLO, GISELE. COVID-19 induces proatherogenic alterations in moderate to severe non-comorbid patients: A single-center observational study. BLOOD CELLS MOLECULES AND DISEASES, v. 92, . (19/05882-8, 13/07467-1)
THOMAZINI, CAMILA MARTOS; SACHETTO, ANA TERESA AZEVEDO; DE ALBUQUERQUE, CYNTHIA ZACCANINI; DE MOURA MATTARAIA, VANIA GOMES; DE OLIVEIRA, ANA KARINA; SERRANO, SOLANGE MARIA DE TOLEDO; LEBRUN, IVO; BARBARO, KATIA CRISTINA; SANTORO, MARCELO LARAMI. Involvement of von Willebrand factor and botrocetin in the thrombocytopenia induced by Bothrops jararaca snake venom. PLoS Neglected Tropical Diseases, v. 15, n. 9, . (13/07467-1, 18/26015-8, 13/20239-8, 19/07618-6, 13/25177-0)
FRANCISQUINI, RODRIGO; BERTON, RAFAEL; SOARES, SANDRO GOMES; PESSOTTI, DAYELLE S.; CAMACHO, MAURICIO F.; ANDRADE-SILVA, DEBORA; BARCICK, UILLA; SERRANO, SOLANGE M. T.; CHAMMAS, ROGER; NASCIMENTO, MARIA C. V.; et al. Community-based network analyses reveal emerging connectivity patterns of protein-protein interactions in murine melanoma secretome. JOURNAL OF PROTEOMICS, v. 232, . (17/22330-3, 15/21660-4, 13/07375-0, 17/24185-0, 14/06579-3, 19/10817-0, 13/07467-1)
JMEL, MOHAMED AMINE; AOUNALLAH, HAJER; BENSAOUD, CHAIMA; MEKKI, IMEN; CHMELAR, JINDRICH; FARIA, FERNANDA; M'GHIRBI, YOUMNA; KOTSYFAKIS, MICHALIS. Insights into the Role of Tick Salivary Protease Inhibitors during Ectoparasite-Host Crosstalk. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 22, n. 2, . (13/07467-1)
LIMA, CARLA; FALCAO, MARIA ALICE PIMENTEL; ANDRADE-BARROS, ALINE INGRID; SENI-SILVA, ANA CAROLINA; GRUND, LIDIANE ZITO; BALOGH, ENIKO; CONCEICAO, KATIA; QUENIAUX, VALERIE F.; RYFFEL, BERNHARD; LOPES-FERREIRA, MONICA. Natterin an aerolysin-like fish toxin drives IL-1 beta-dependent neutrophilic inflammation mediated by caspase-1 and caspase-11 activated by the inflammasome sensor NLRP6. International Immunopharmacology, v. 91, . (18/17413-0, 19/10500-7, 13/07467-1)
CALDERANO, SIMONE GUEDES; NISHIYAMA JUNIOR, MILTON YUTAKA; MARINI, MARJORIE; NUNES, NATHAN DE OLIVEIRA; REIS, MARCELO DA SILVA; PATANE, JOSE SALVATORE LEISTER; DA SILVEIRA, JOSE FRANCO; DA CUNHA, JULIA PINHEIRO CHAGAS; ELIAS, MARIA CAROLINA. Identification of Novel Interspersed DNA Repetitive Elements in the Trypanosoma cruzi Genome Associated with the 3 ' UTRs of Surface Multigenic Families. GENES, v. 11, n. 10, p. 20-pg., . (16/50050-2, 13/07467-1)
BATISTA, MARCELO; MONTONI, FABIO; CAMPOS, CRISTIANO; NOGUEIRA, RONALDO; ARMELIN, HUGO A.; REIS, MARCELO S.. A Framework for Inference and Selection of Cell Signaling Pathway Dynamic Models. ADVANCES IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, BSB 2023, v. 13954, p. 12-pg., . (20/10329-3, 19/24580-2, 13/07467-1, 21/04355-4, 20/08555-5, 19/21619-5)
EVANGELISTA, BIANCA G.; GIARDINI, ALINE C.; HOSCH, NATALIA G.; SANT'ANNA, MORENA B.; MARTINS, BARBARA B.; NETO, BEATRIZ S.; CHACUR, MARUCIA; PAGANO, ROSANA L.; PICOLO, GISELE; ZAMBELLI, VANESSA O.. Aldehyde dehydrogenase-2 deficiency aggravates neuroinflammation , nociception, and motor impairment in a mouse model of multiple sclerosis. Free Radical Biology and Medicine, v. 225, p. 9-pg., . (21/02897-4, 15/01254-1, 13/07467-1, 15/26079-8)
ROSA, JOAO GABRIEL SANTOS; DISNER, GEONILDO RODRIGO; PINTO, FELIPE JUSTINIANO; LIMA, CARLA; LOPES-FERREIRA, MONICA. Revisiting Retinal Degeneration Hallmarks: Insights from Molecular Markers and Therapy Perspectives. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 17, p. 23-pg., . (21/08891-8, 13/07467-1)
PINTO, BRUNA FERNANDES; LOPES, PRISCILA HESS; TRUFEN, CARLOS EDUARDO MADUREIRA; CHING, ANA TUNG CHING; DE AZEVEDO, INACIO DE LOYOLA M. JUNQUEIRA; NISHIYAMA-JR, MILTON YUTAKA; DE SOUZA, MARCELO MEDINA; POHL, PAULA C.; TAMBOURGI, DENISE V.. Differential Cellular Responses to Class I and II Sphingomyelinase D: Unraveling the Mechanisms of Loxosceles Venom-Induced Dermonecrosis and Potential Therapeutic Targets. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 26, n. 7, p. 20-pg., . (20/03718-3, 13/07467-1)
FERNANDES, DAYANNE CARLA; SILVA-DE-FRANCA, FELIPE; POHL, PAULA CRISTIANE; ETO, SILAS FERNANDES; SARDINHA, LUIZ ROBERTO; LAMBRIS, JOHN D.; TAMBOURGI, DENISE, V. Cp40-mediated complement C3 inhibition dampens inflammasome activation and inflammatory mediators storm induced by Bitis arietans venom. International Immunopharmacology, v. 147, p. 17-pg., . (13/07467-1, 19/27348-3)
SEIF, ELIAS JORGE MUNIZ; SILVA JR, PEDRO ISMAEL. In silico bioprospecting of receptors for Oligoventin: An antimicrobial peptide isolated from spider eggs of Phoneutria nigriventer. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 248, p. 10-pg., . (13/07467-1)
TORRES, KATIA ANDREA DE MENEZES; LIMA, SONIA MARIA ROLIM ROSA; GAMBERINI, MARIA THEREZA; RODRIGUES, DOMINGOS SAVIO; SILVA, PEDRO ISMAEL. Group B Strep During Pregnancy and Allium sativum L.. JOURNAL OF HERBAL MEDICINE, v. 48, p. 7-pg., . (13/07467-1)
DE LIMA, CINTHYA LAIS; POHL, PAULA C.; VILLAS-BOAS, ISADORA M.; PIDDE, GISELLE; TAMBOURGI, DENISE V.. Investigating the impact of Premolis semirufa caterpillar bristle toxins on human chondrocyte activation and inflammation. PLoS Neglected Tropical Diseases, v. 19, n. 2, p. 19-pg., . (15/50040-4, 13/07467-1, 20/13139-0)
LOPES-FERREIRA, MONICA; FARINHA, LUIZ ROGERIO LUDWIG; COSTA, YASMIN STEFANIE OLIVEIRA; PINTO, FELIPE JUSTINIANO; DISNER, GEONILDO RODRIGO; DA ROSA, JOAO GABRIEL DOS SANTOS; LIMA, CARLA. Pesticide-Induced Inflammation at a Glance. TOXICS, v. 11, n. 11, p. 15-pg., . (13/07467-1, 21/08891-8, 21/06084-8, 19/27677-7)
NOLASCO, MATHEUS; MARIANO, DOUGLAS O. C.; PIMENTA, DANIEL C.; DE FREITAS, HUMBERTO FONSECA; PITA, SAMUEL SILVA DA ROCHA; BRANCO, ALEXSANDRO. Oligopeptides analysis in spiderhawk's venom (Pepsis decorata Perty, 1833, Hymenoptera: Pompilidae). PEPTIDE SCIENCE, v. 116, n. 4, p. 9-pg., . (13/07467-1)
FREITAS-DE-SOUSA, LUCIANA A.; COLOMBINI, MONICA; SOUZA, VINICIUS C.; SILVA, JOANDERSON P. C.; MOTA-DA-SILVA, AGEANE; ALMEIDA, MARLLUS R. N.; MACHADO, REGINALDO A.; FONSECA, WIRVEN L.; SARTIM, MARCO A.; SACHETT, JACQUELINE; et al. Venom Composition of Neglected Bothropoid Snakes from the Amazon Rainforest: Ecological and Toxinological Implications. TOXINS, v. 16, n. 2, p. 22-pg., . (22/10344-8, 13/07467-1, 22/12660-4, 16/50127-5)
DEL SANTOS, NAYARA; VAZQUEZ-RAMIREZ, RICARDO; MENDES, ELIZABETH; SILVA JR, PEDRO ISMAEL; BORGES, MONAMARIS MARQUES. Impact of Mygalin on Inflammatory Response Induced by Toll-like Receptor 2 Agonists and IFN-γ Activation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 25, n. 19, p. 20-pg., . (23/08292-2, 13/07467-1, 20/08182-4)
SANT'ANNA, MORENA BRAZIL; KIMURA, LOUISE FAGGIONATO; VIEIRA, WILLIANS FERNANDO; ZAMBELLI, VANESSA OLZON; NOVAES, LEONARDO SANTANA; HOSCH, NATALIA GABRIELE; PICOLO, GISELE. Environmental factors and their impact on chronic pain development and maintenance. PHYSICS OF LIFE REVIEWS, v. 48, p. 22-pg., . (19/21158-8, 19/26414-2, 21/14831-8, 13/07467-1, 19/05882-8, 19/24631-6, 18/19599-3, 23/05626-7, 21/10982-1)
DA SILVA, GLORIA MARIA; BERTO DE SOUZA, DANIEL HENRIQUE; WAITMAN, KAROLINE B.; EBRAM, MATTEO CELANO; FESSEL, MELISSA R.; ZAINESCU, IULIU CEZAR; PORTARO, FERNANDA C.; HERAS, MONTSE; DE ANDRADE, SONIA A.. Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, p. 7-pg., . (17/04321-7, 13/07467-1)
KODAMA, ROBERTO TADASHI; KUNIYOSHI, ALEXANDRE KAZUO; FERNANDES DA SILVA, CRISTIANE CASTILHO; CAJADO-CARVALHO, DANIELA; DUZZI, BRUNO; MARIANO, DOUGLAS CEOLIN; PIMENTA, DANIEL C.; BORGES, RAFAEL; DA SILVA, WILMAR DIAS; VIEIRA PORTARO, FERNANDA CALHETA. A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 26, p. 13-pg., . (15/15364-3, 15/13124-5, 13/07467-1, 13/15344-7, 11/02061-1)
VITARELLI, MARCELA DE OLIVEIRA; FRANCO, THIAGO ANDRADE; PIRES, DAVID DA SILVA; LIMA, ALEX RANIERI JERONIMO; VIALA, VINCENT LOUIS; KRAUS, AMELIE JOHANNA; DE AZEVEDO, INACIO DE LOIOLA MEIRELLES JUNQUEIRA; DA CUNHA, JULIA PINHEIRO CHAGAS; ELIAS, MARIA CAROLINA. Integrating high-throughput analysis to create an atlas of replication origins in Trypanosoma cruzi in the context of genome structure and variability. MBIO, v. 15, n. 4, p. 25-pg., . (16/50050-2, 19/04483-2, 13/07467-1, 20/00694-6, 17/07693-2, 22/01900-4)
DIAS, MATHEUS HENRIQUE; FRISKES, ANOEK; WANG, SIYING; NETO, JOAO M. FERNANDES; VAN GEMERT, FRANK; MOURRAGUI, SOUFIANE; PAPAGIANNI, CHRYSA; KUIKEN, HENDRIK J.; MAINARDI, SARA; ALVAREZ-VILLANUEVA, DANIEL; et al. Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy. CANCER DISCOVERY, v. 14, n. 7, p. 26-pg., . (13/07467-1, 19/10753-2, 20/10277-3)
MENDONCA, R. Z.; NASCIMENTO, R. M.; FERNANDES, A. C. O.; SILVA JR, P. I.. Antiviral action of aqueous extracts of propolis from Scaptotrigona aff. postica (Hymenoptera; Apidae) against Zica, Chikungunya, and Mayaro virus. SCIENTIFIC REPORTS, v. 14, n. 1, p. 14-pg., . (13/07467-1)
BATISTA-FILHO, JOAO; FALCAO, MARIA ALICE PIMENTEL; MALESKI, ADOLFO LUIS ALMEIDA; SOARES, AMANDA BEATRIZ SILVA; BALAN-LIMA, LETICIA; DISNER, GEONILDO RODRIGO; LIMA, CARLA; LOPES-FERREIRA, MONICA. Early preclinical screening using zebrafish (Danio rerio) reveals the safety of the candidate anti-inflammatory therapeutic agent TnP. TOXICOLOGY REPORTS, v. 8, p. 13-22, . (13/07467-1)
A. LILLO; F. CARVAJAL-CAICONTE; W. VITAL; P. I. SILVA JUNIOR; E. J. PAREDES-GAMERO; M. ALVEAR; A. MIRANDA. Propriedades bioativas de extratos de folhas e frutos de Persea lingue Ness (Lauraceae). Brazilian Journal of Biology, v. 83, . (13/07467-1)
BADARI, JULIANA CUOCO; DIAZ-ROA, ANDREA; TEIXEIRA ROCHA, MARISA MARIA; MENDONCA, RONALDO ZUCATELLI; SILVA JUNIOR, PEDRO ISMAEL DA. Patagonin-CRISP: Antimicrobial Activity and Source of Antimicrobial Molecules in Duvernoy's Gland Secretion (Philodryas patagoniensis Snake). FRONTIERS IN PHARMACOLOGY, v. 11, . (16/24867-1, 13/07467-1)
MORENO, RAFAELA INDALECIO; ZAMBELLI, VANESSA O.; PICOLO, GISELE; CURY, YARA; MORANDINI, ANDRE C.; MARQUES, ANTONIO CARLOS; SCIANI, JULIANA MOZER. Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation. MARINE DRUGS, v. 20, n. 10, p. 12-pg., . (19/19929-6, 13/07467-1)
CANTO, AMANDA M.; GODOI, ALEXANDRE B.; MATOS, ALEXANDRE H. B.; GERALDIS, JAQUELINE C.; ROGERIO, FABIO; ALVIM, MARINA K. M.; YASUDA, CLARISSA L.; GHIZONI, ENRICO; TEDESCHI, HELDER; VEIGA, DIOGO F. T.; et al. Benchmarking the proteomic profile of animal models of mesial temporal epilepsy. ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, v. 9, n. 4, p. 14-pg., . (16/19484-6, 13/07559-3, 19/00213-0, 13/07467-1, 15/12960-4)
FERREIRA, JESSICA DE ALCANTARA; SILVA, DILZA TREVISAN; DE TOLEDO SERRANO, SOLANGE MARIA; MENEZES, MILENE CRISTINA. EXPRESSION OF MUTANT FORMS OF THE NON-CATALYTIC DOMAINS OF A METALLOPROTEINASE OF THE VENOM OF THE SNAKE BOTHROPS JARARACA USING A CELL-FREE EXPRESSION SYSTEM. Toxicon, v. 168, p. 2-pg., . (13/07467-1, 17/09648-4)
DISNER, GEONILDO RODRIGO; FALCAO, MARIA ALICE PIMENTEL; LIMA, CARLA; LOPES-FERREIRA, MONICA. Zebrafish Beyond the Bench: The 'Plataforma Zebrafish Open Doors' Programme. ATLA-ALTERNATIVES TO LABORATORY ANIMALS, v. 49, n. 5, p. 7-pg., . (19/27677-7, 18/17413-0, 13/07467-1)
DOS SANTOS, GUILHERME BRZOSKOWSKI; DA SILVA, EDILEUZA DANIELI; KITANO, EDUARDO SHIGUEO; BATTISTELLA, MARIA EDUARDA; MONTEIRO, KARINA MARIANTE; DE LIMA, JEFERSON CAMARGO; FERREIRA, HENRIQUE BUNSELMEYER; DE TOLEDO SERRANO, SOLANGE MARIA; ZAHA, ARNALDO. Proteomic profiling of hydatid fluid from pulmonary cystic echinococcosis. PARASITES & VECTORS, v. 15, n. 1, p. 19-pg., . (13/07467-1)
HOSCH, NATALIA G.; MARTINS, BARBARA B.; ALCANTARA, QUEREN A.; BUFALO, MICHELLE CRISTIANE; NETO, BEATRIZ S.; CHUDZINKI-TAVASSI, ANA MARISA; SANTA-CECILIA, FLAVIA V.; CURY, YARA; ZAMBELLI, VANESSA O.. Wnt signaling is involved in crotalphine-induced analgesia in a rat model of neuropathic pain. European Journal of Pharmacology, v. 959, p. 13-pg., . (20/04998-0, 15/50040-4, 13/07467-1, 20/13139-0)
NACHTIGALL, PEDRO G.; DURHAM, ALAN M.; ROKYTA, DARIN R.; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages. GIGASCIENCE, v. 13, p. 17-pg., . (18/26520-4, 13/07467-1, 22/04988-0, 16/50127-5)
GABRILI, JOEL J. M.; VILLAS-BOAS, ISADORA MARIA; PIDDE, GISELLE; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; WOODRUFF, TRENT M.; TAMBOURGI, DENISE, V. Complement System Inhibition Modulates the Inflammation Induced by the Venom of Premolis semirufa, an Amazon Rainforest Moth Caterpillar. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 21, p. 20-pg., . (13/07467-1)
LOBBA, ALINE R. M.; ALVAREZ-FLORES, MIRYAM PAOLA; FESSEL, MELISSA REGINA; BURI, MARCUS VINICIUS; OLIVEIRA, DOUGLAS S. S.; GOMES, RENATA N. N.; CUNEGUNDES, PRISCILA S. S.; DEOCESANO-PEREIRA, CARLOS; CINEL, VICTOR D. D.; CHUDZINSKI-TAVASSI, ANA M. M.. A Kunitz-type inhibitor from tick salivary glands: A promising novel antitumor drug candidate. FRONTIERS IN MOLECULAR BIOSCIENCES, v. 9, p. 16-pg., . (20/13139-0, 18/20469-7, 13/07467-1, 18/10937-3, 15/50040-4)
TEIXEIRA, NATHALIA BERNARDES; PICOLO, GISELE; GIARDINI, ALINE CAROLINA; BOUMEZBEUR, FAWZI; POTTIER, GERALDINE; KUHNAST, BERTRAND; SERVENT, DENIS; BENOIT, EVELYNE. Alterations of peripheral nerve excitability in an experimental autoimmune encephalomyelitis mouse model for multiple sclerosis. JOURNAL OF NEUROINFLAMMATION, v. 17, n. 1, p. 14-pg., . (13/07467-1, 11/17974-2)
DE SOUZA, IZADORA; CLARES RAMALHO, MARIA CAROLINA; GUEDES, CAMILA BANCA; ARAUJO OSAWA, ISABELI YUMI; SEREGNI MONTEIRO, LINDA KAROLYNNE; GOMES, LUCIANA RODRIGUES; REILY ROCHA, CLARISSA RIBEIRO. Ferroptosis Modulation: Potential Therapeutic Target for Glioblastoma Treatment. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 13, p. 21-pg., . (19/27080-0, 19/15320-7, 19/19435-3, 13/07467-1, 19/26268-6, 19/21745-0)
DA SILVA, BRUNA S.; DIAZ-ROA, ANDREA; YAMANE, ERICA S.; HAYASHI, MIRIAN A. F.; SILVA JR, PEDRO ISMAEL. Doderlin: isolation and characterization of a broad-spectrum antimicrobial peptide from Lactobacillus acidophilus. Research in Microbiology, v. 174, n. 3, p. 12-pg., . (13/07467-1)
SOUZA, GLAUCIA MENDES; VAN SLUYS, MARIE-ANNE; LEMBKE, CAROLINA GIMILIANI; LEE, HAYAN; MARGARIDO, GABRIEL RODRIGUES ALVES; HOTTA, CARLOS TAKESHI; GAIARSA, JONAS WEISSMANN; DINIZ, AUGUSTO LIMA; OLIVEIRA, MAURO DE MEDEIROS; FERREIRA, SAVIO DE SIQUEIRA; et al. Assembly of the 373k gene space of the polyploid sugarcane genome reveals reservoirs of functional diversity in the world's leading biomass crop. GIGASCIENCE, v. 8, n. 12, p. 18-pg., . (14/50921-8, 17/02842-0, 08/52074-0, 15/22993-7, 08/52146-0, 13/18322-4, 12/51062-3, 13/07467-1, 17/02270-6, 11/50761-2, 13/23048-9, 16/06917-1, 15/15346-5, 16/17545-8)
SILVA, DEBORA ANDRADE; ROSA-FERNANDES, LIVIA; PALMISANO, GIUSEPPE; TRAVAGLIA-CARDOSO, SILVIA R.; TOLEDO SERRANO, SOLANGE M.; LARSEN, MARTIN R.. Exploring the glycosylation levels of snake venom proteins by mass spectrometry: microheterogeneity determination of sweet spots in toxins of Bothrops snake genus. MOLECULAR & CELLULAR PROTEOMICS, v. 18, n. 8, p. 1-pg., . (13/07467-1, 18/08794-0, 16/16935-7)
SANT'ANNA, M. B.; GIARDINI, A. C.; LOPES, F. S.; KIMURA, L. F.; CHACUR, M.; PAGANO, R. L.; ZAMBELLI, V. O.; SANT'ANNA, O. A.; PICOLO, G.. RATTLESNAKE VENOM COMPONENTS IN THE CONTROL OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS: IMMUNOMODULATORY PROPERTIES POTENTIATED BY SILICA SBA-15. Toxicon, v. 182, p. 1-pg., . (13/07467-1, 17/17844-8)
RUSSO, LILIAN C.; ARAUJO, CHRISTIANE B.; IWAI, LEO K.; FERRO, EMER S.; FORTI, FABIO L.. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells. JOURNAL OF PROTEOMICS, v. 151, n. SI, p. 24-32, . (13/07467-1, 08/58264-5, 15/03983-0)
ALMEIDA, DIEGO DANTAS; KITAJIMA, JOAO PAULO; NISHIYAMA, JR., MILTON YUTAKA; CONDOMITTI, GEORGE WILLIAN; DE OLIVEIRA, URSULA CASTRO; SETUBAL, JOAO CARLOS; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). MITOCHONDRIAL DNA PART B-RESOURCES, v. 1, p. 907-908, . (13/07467-1, 13/07974-0, 12/00177-5)
SILVA, MAKSWELL ALMEIDA; LOPES, DAIANA SILVA; TEIXEIRA, SAMUEL COTA; CIRILO GIMENES, SARAH NATALIE; VASCONCELOS AZEVEDO, FERNANDA VAN PETTEN; POLLONI, LORENA; BORGES, BRUNA CRISTINA; DA SILVA, MARCELO SANTOS; BARBOSA, MARCELO JOSE; DE OLIVEIRA JUNIOR, ROBSON JOSE; et al. Genotoxic effects of BnSP-6, a Lys-49 phospholipase A(2) (PLA(2)) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells. International Journal of Biological Macromolecules, v. 118, n. A, p. 311-319, . (13/07467-1, 14/24170-5)
DO NASCIMENTO, SORAIA MARIA; DE OLIVEIRA, URSULA CASTRO; NISHIYAMA-JR, MILTON YUTAKA; TASHIMA, ALEXANDRE KEIJI; DA SILVA JUNIOR, PEDRO ISMAEL. Presence of a neprilysin on Avicularia juruensis (Mygalomorphae: Theraphosidae) venom. Toxin Reviews, . (13/07467-1)
FALCAO, MARIA ALICE PIMENTEL; WALKER, CRISTIANI ISABEL BANDERO; DISNER, GEONILDO RODRIGO; BATISTA-FILHO, JOAO; SOARES, AMANDA BEATRIZ SILVA; BALAN-LIMA, LETICIA; LIMA, CARLA; LOPES-FERREIRA, MONICA. nockdown of miR-26a in zebrafish leads to impairment of the anti-inflammatory function of TnP in the control of neutrophili. FISH & SHELLFISH IMMUNOLOGY, v. 114, p. 301-310, . (13/07467-1)
MONICA LOPES-FERREIRA; LIDIANE ZITO GRUND; CARLA LIMA. Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 20, p. 1-12, . (04/15112-0, 08/55395-1, 12/50294-8, 13/07467-1, 03/13751-2, 98/14307-9)
DOUGLAS O. MARIANO; JULIANA M. SCIANI; MARTA M. ANTONIAZZI; CARLOS JARED; KATIA CONCEIÇÃO; DANIEL C. PIMENTA. Quantity - but not diversity - of secreted peptides and proteins increases with age in the tree frog Pithecopus nordestinus. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, . (13/07467-1)
MYAMOTO, D. T.; PIDDE-QUEIROZ, G.; PEDROSO, A.; GONCALVES-DE-ANDRADE, R. M.; VAN DEN SERG, C. W.; TAMBOURGI, D. V.. Characterization of the gene encoding component C3 of the complement system from the spider Loxosceles laeta venom glands: Phylogenetic implications. Immunobiology, v. 221, n. 9, p. 953-963, . (13/07467-1)
ARRUDA, GIAN LUCAS M.; VIGERELLI, HUGO; BUFALO, MICHELLE C.; LONGATO, GIOVANNA B.; VELOSO, RODINEI V.; ZAMBELLI, VANESSA O.; PICOLO, GISELE; CURY, YARA; MORANDINI, ANDRE C.; MARQUES, ANTONIO CARLOS; et al. Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect. BIOMED RESEARCH INTERNATIONAL, v. 2021, . (15/21007-9, 15/50040-4, 16/06137-6, 19/19929-6, 13/07467-1, 11/50242-5)
DE MENEZES TORRES, KATIA ANDREA; ROLIM ROSA LIMA, SONIA MARIA; BRANDAO TORRES, LUCE MARIA; GAMBERINI, MARIA THEREZA; DA SILVA JUNIOR, PEDRO ISMAEL. Garlic: An Alternative Treatment for Group B Streptococcus. MICROBIOLOGY SPECTRUM, v. 9, n. 3, . (13/07467-1)
LOPES, PRISCILA HESS; FUKUSHIMA, CAROLINE SAYURI; SHOJI, ROSANA; BERTANI, ROGERIO; TAMBOURGI, V, DENISE. Sphingomyelinase D Activity in Sicarius tropicus Venom: Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family. TOXINS, v. 13, n. 4, . (15/17053-5, 13/07467-1)
ANDRADE-TOMAZ, MARINA; DE SOUZA, IZADORA; RIBEIRO REILY ROCHA, CLARISSA; RODRIGUES GOMES, LUCIANA. The Role of Chaperone-Mediated Autophagy in Cell Cycle Control and Its Implications in Cancer. CELLS, v. 9, n. 9, . (13/07467-1, 19/21745-0, 19/19435-3)
DO NASCIMENTO, SORAIA MARIA; DE OLIVEIRA, URSULA CASTRO; NISHIYAMA-JR, MILTON YUTAKA; TASHIMA, ALEXANDRE KEIJI; DA SILVA JUNIOR, PEDRO ISMAEL. Presence of a neprilysin on Avicularia juruensis (Mygalomorphae: Theraphosidae) venom. Toxin Reviews, v. 41, n. 2, p. 10-pg., . (13/07467-1)
ASEGA, AMANDA F.; BARROS, BIANCA C. S. C.; CHAVES, ALISON F. A.; OLIVEIRA, ANA K.; BERTHOLIM, LUCIANA; KITANO, EDUARDO S.; SERRANO, SOLANGE M. T.. Mouse skin peptidomic analysis of the hemorrhage induced by a snake venom metalloprotease. Amino Acids, v. 55, n. 9, p. 17-pg., . (21/10570-5, 13/07467-1, 20/12317-2, 10/17328-0, 11/11308-0, 11/16623-1, 10/00206-0)
BALDON, ESTEVAM JOSE; MARENGO, ELIANA BLINI; DE FRANCO, MARCELO; STAROBINAS, NANCY; BUENO, VALQUIRIA; SANT'ANNA, OSVALDO AUGUSTO. Mycobacterium leprae Hsp65 administration reduces the lifespan of aged high antibody producer mice. IMMUNITY & AGEING, v. 11, . (13/07467-1)
CALDERANO, SIMONE; GODOY, PATRICIA; SOARES, DAIANE; SANT'ANNA, OSVALDO AUGUSTO; SCHENKMAN, SERGIO; ELIAS, M. CAROLINA. ORC1/CDC6 and MCM7 distinct associate with chromatin through Trypanosoma cruzi life cycle. Molecular and Biochemical Parasitology, v. 193, n. 2, p. 110-113, . (13/07467-1, 09/53693-8)
DOS SANTOS, JANAINA CARDOSO; GRUND, LIDIANE ZITO; SEIBERT, CARLA SIMONE; MARQUES, ELINEIDE EUGENIO; SOARES, ANDERSON BRITO; QUESNIAUX, VALERIE F.; RYFFEL, BERNHARD; LOPES-FERREIRA, MONICA; LIMA, CARLA. Stingray venom activates IL-33 producing cardiomyocytes, but not mast cell, to promote acute neutrophil-mediated injury. SCIENTIFIC REPORTS, v. 7, . (13/07467-1, 15/12224-6, 15/12225-2)
FREITAS-DE-SOUSA, LUCIANA APARECIDA; COLOMBINI, MONICA; LOPES-FERREIRA, MONICA; SERRANO, SOLANGE M. T.; MOURA-DA-SILVA, ANA MARIA. Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase. TOXINS, v. 9, n. 8, . (13/07467-1, 16/50127-5, 14/26058-8)
ZAMBELLI, VANESSA O.; CHEN, CHE-HONG; GROSS, ERIC R.. Reactive aldehydes: an initial path to develop precision medicine for pain control. ANNALS OF TRANSLATIONAL MEDICINE, v. 3, n. 17, . (13/07467-1)
IQBAL, ASIF; GOLDFEDER, MAURICIO BARBUGIANI; MARQUES-PORTO, RAFAEL; ASIF, HUMA; DE SOUZA, JEAN GABRIEL; FARIA, FERNANDA; CHUDZINSKI-TAVASSI, ANA MARISA. Revisiting antithrombotic therapeutics; sculptin, a novel specific, competitive, reversible, scissile and tight binding inhibitor of thrombin. SCIENTIFIC REPORTS, v. 7, . (13/07467-1, 15/50040-4)
DE LIMA, LOYZE P.; CALDERANO, SIMONE G.; DA SILVA, MARCELO S.; DE ARAUJO, CHRISTIANE B.; VASCONCELOS, ELTON J. R.; IWAI, LEO K.; PEREIRA, CLAUDIO A.; FRAGOSO, STENIO P.; CAROLINA ELIAS, M.. Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi. SCIENTIFIC REPORTS, v. 9, . (13/07467-1, 14/24170-5, 14/13375-5, 16/50050-2)
BOUFLEUR, PAMELA; SCIANI, JULIANA MOZER; GOLDFEDER, MAURICIO; FARIA, FERNANDA; BRANCO, VANIA; CHUDZINSKI-TAVASSI, ANA MARISA. Biodistribution and Pharmacokinetics of Amblyomin-X, a Novel Antitumour Protein Drug in Healthy Mice. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, v. 44, n. 1, p. 111-120, . (13/07467-1)
GARCIA, P. R. A. F.; BICEV, R. N.; OLIVEIRA, C. L. P.; SANT'ANNA, O. A.; FANTINI, M. C. A.. Protein encapsulation in SBA-15 with expanded pores. Microporous and Mesoporous Materials, v. 235, p. 59-68, . (13/07467-1)
BRANCO, VANIA G.; IQBAL, ASIF; ALVAREZ-FLORES, MIRYAM P.; SCIANI, JULIANA M.; DE ANDRADE, SONIA A.; IWAI, LEO K.; SERRANO, SOLANGE M. T.; CHUDZINSKI-TAVASSI, ANA M.. Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1864, n. 10, p. 1428-1435, . (13/07467-1, 15/50040-4)
DE SOUZA, JEAN GABRIEL; MORAIS, KATIA L. P.; ANGLES-CANO, EDUARDO; BOUFLEUR, PAMELA; DE MELLO, EVANDRO SOBROZA; MARIA, DURVANEI AUGUSTO; TAEMI ORIGASSA, CLARICE SILVIA; ZAMPOLLI, HAMILTON DE CAMPOS; SARAIVA CAMARA, NIELS OLSEN; BERRA, CAROLINA MARIA; et al. Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model. ONCOTARGET, v. 7, n. 38, p. 62255-62266, . (13/07467-1, 15/50040-4, 12/02270-2, 10/52669-3, 12/06944-8, 10/07958-7)
DA SILVA, MARCELO SANTOS; SEGATTO, MARCELA; PAVANI, RAPHAEL SOUZA; GUTIERREZ-RODRIGUES, FERNANDA; BISPO, VANDERSON DA SILVA; GENNARI DE MEDEIROS, MARISA HELENA; CALADO, RODRIGO TOCANTINS; ELIAS, MARIA CAROLINA; NOGUEIRA CANO, MARIA ISABEL. Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, v. 1864, n. 1, p. 138-150, . (13/07467-1, 12/50263-5, 14/02978-0, 14/24170-5, 15/10580-0, 13/07937-8)
SATO, ANA CLAUDIA; BOSCH, ROSEMARY VIOLA; ALVES WILL, SONIA ELISABETE; ALVAREZ-FLORES, MIRYAM PAOLA; GOLDFEDER, MAURICIO BARBUGIANI; MESQUITA PASQUALOTO, KERLY FERNANDA; VAZ GALVAO DA SILVA, BRBARA ATHAYDE; DE ANDRADE, SONIA APARECIDA; CHUDZINSKI-TAVASSI, ANA MARISA. Exploring the in vivo wound healing effects of a recombinant hemolin from the caterpillar Lonomia obliqua. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 22, . (13/07467-1, 13/06892-0)
ATASHPAZ-GARGARI, ESMAEIL; REIS, MARCELO S.; BRAGA-NETO, ULISSES M.; BARRERA, JUNIOR; DOUGHERTY, EDWARD R.. A fast Branch-and-Bound algorithm for U-curve feature selection. PATTERN RECOGNITION, v. 73, p. 172-188, . (13/07467-1, 15/01587-0)
SANTORO, MARCELO LARAMI; DO CARMO, THAIS; LOPES CUNHA, BRUNA HELOISA; ALVES, ANDRE FONSECA; ZELANIS, ANDRE; DE TOLEDO SERRANO, SOLANGE MARIA; GREGO, KATHLEEN FERNANDES; SANT'ANNA, SAVIO STEFANINI; BARBARO, KATIA CRISTINA; FERNANDES, WILSON. Ontogenetic Variation in Biological Activities of Venoms from Hybrids between Bothrops erythromelas and Bothrops neuwiedi Snakes. PLoS One, v. 10, n. 12, . (13/07467-1, 10/08162-1, 13/13548-4, 08/02996-8, 09/15413-3, 13/25177-0)
CHUDZINSKI-TAVASSI, ANA MARISA; MORAIS, KATIA L. P.; FERNANDES PACHECO, MARIO THIEGO; MESQUITA PASQUALOTO, KERLY FERNANDA; DE SOUZA, JEAN GABRIEL. Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates. BIOMEDICINE & PHARMACOTHERAPY, v. 77, p. 14-19, . (13/07467-1, 10/52669-3, 11/05969-4, 98/14307-9, 10/07958-7)
MYAMOTO, DANIELA TIEMI; PIDDE-QUEIROZ, GISELLE; GONCALVES-DE-ANDRADE, RUTE MARIA; PEDROSO, AURELIO; VAN DEN BERG, CARMEN W.; TAMBOURGI, DENISE V.. Characterization of a Gene Coding for the Complement System Component FB from Loxosceles laeta Spider Venom Glands. PLoS One, v. 11, n. 1, . (13/07467-1)
ELIAS, M. CAROLINA; FLOETER-WINTER, LUCILE M.; MENA-CHALCO, JESUS P.. The dynamics of Brazilian protozoology over the past century. Memórias do Instituto Oswaldo Cruz, v. 111, n. 1, p. 67+, . (13/07467-1)
DE LUNA VITORINO, FRANCISCA NATHALIA; MONTONI, FABIO; MORENO, JAQUELINE NEVES; DE SOUZA, BRUNO FERREIRA; LOPES, MARIANA DE CAMARGO; CORDEIRO, BARBARA; FONSECA, CECILIA SELLA; GILMORE, JOSHUA M.; SARDIU, MIHAELA I.; REIS, MARCELO SILVA; et al. FGF2 Antiproliferative Stimulation Induces Proteomic Dynamic Changes and High Expression of FOSB and JUNB in K-Ras-Driven Mouse Tumor Cells. PROTEOMICS, v. 18, n. 17, . (11/22619-7, 13/07467-1)
ALVES, CERES LUCIANA; REPOLES, BRUNO MARCAL; DA SILVA, MARCELO SANTOS; MENDES, ISABELA CECILIA; MARIN, PAULA ANDREA; NASCIMENTO AGUIAR, PEDRO HENRIQUE; SANTOS, SELMA DA SILVA; FRANCO, GLORIA REGINA; MACEDO, ANDREA MARA; JUNHO PENA, SERGIO DANILO; et al. The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi. SCIENTIFIC REPORTS, v. 8, . (13/07467-1, 14/24170-5, 16/50050-2)
BORGES, ALYSSA R.; TOLEDO, DANIEL A.; FERMINO, BRUNO R.; DE OLIVEIRA, JOSE CARLOS; SILBER, ARIEL MARIANO; ELIAS, MARIA CAROLINA; D'AVILA, HELOISA; SCOPEL, KEZIA K. G.. In Vitro Cellular Division of Trypanosoma abeli Reveals Two Pathways for Organelle Replication. Journal of Eukaryotic Microbiology, v. 66, n. 3, p. 385-392, . (13/07467-1)
DE ARAUJO, CHRISTIANE B.; CALDERANO, SIMONE G.; ELIAS, MARIA CAROLINA. The Dynamics of Replication in Trypanosoma cruzi Parasites by Single-Molecule Analysis. Journal of Eukaryotic Microbiology, v. 66, n. 3, p. 514-518, . (13/07467-1, 16/50050-2, 14/13375-5)
LIBERATO, TARCISIO; PAOLO TRONCONE, LANFRANCO RANIERI; YAMASHIRO, EDSON T.; SERRANO, SOLANGE M. T.; ZELANIS, ANDRE. High-resolution proteomic profiling of spider venom: expanding the toxin diversity of Phoneutria nigriventer venom. Amino Acids, v. 48, n. 3, p. 901-906, . (13/07467-1, 11/08514-8, 02/04545-7)
PAVANI, RAPHAEL SOUZA; DA SILVA, MARCELO SANTOS; HENRIQUE FERNANDES, CARLOS ALEXANDRE; MORINI, FLAVIA SOUZA; ARAUJO, CHRISTIANE BEZERRA; DE MATTOS FONTES, MARCOS ROBERTO; SANT'ANNA, OSVALDO AUGUSTO; MACHADO, CARLOS RENATO; CANO, MARIA ISABEL; FRAGOSO, STENIO PERDIGAO; et al. Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Neglected Tropical Diseases, v. 10, n. 12, . (14/13375-5, 14/24170-5, 13/17864-8, 14/02978-0, 13/07467-1, 15/10580-0)
SCARAMUZZI, KARINA; TANAKA, GABRIELA D.; MARIANO NETO, FRANCISCO; GARCIA, PAULO R. A. F.; GABRILI, JOEL J. M.; OLIVEIRA, DENISE C. A.; TAMBOURGI, DENISE V.; MUSSALEM, JULIANA S.; PAIXAO-CAVALCANTE, DANIELLE; D'AZEREDO ORLANDO, MARCOS T.; et al. Nanostructured SBA-15 silica: An effective protective vehicle to oral hepatitis B vaccine immunization. Nanomedicine-Nanotechnology Biology and Medicine, v. 12, n. 8, p. 2241-2250, . (13/07467-1)
LEANDRO DE JESUS, TERESA CRISTINA; CALDERANO, SIMONE GUEDES; DE LUNA VITORINO, FRANCISCA NATHALIA; LLANOS, RICARDO PARIONA; LOPES, MARIANA DE CAMARGO; DE ARAUJO, CHRISTIANE BEZERRA; THIEMANN, OTAVIO HENRIQUE; REIS, MARCELO DA SILVA; ELIAS, MARIA CAROLINA; CHAGAS DA CUNHA, JULIA PINHEIRO. Quantitative Proteomic Analysis of Replicative and Nonreplicative Forms Reveals Important Insights into Chromatin Biology of Trypanosoma cruzi. MOLECULAR & CELLULAR PROTEOMICS, v. 16, n. 1, p. 23-38, . (13/07467-1, 11/22619-7)
ROSA SAYEGH, RAPHAEL SANTA; CORREIA BATISTA, ISABEL DE FATIMA; DE MELO, ROBSON LOPES; RISKE, KARIN A.; DAFFRE, SIRLEI; MONTICH, GUILLERMO; DA SILVA JUNIOR, PEDRO ISMAEL. Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles. PLoS One, v. 11, n. 12, . (13/07467-1)
KOMEGAE, EVILIN NANAME; MATOZO SOUZA, TAIS APARECIDA; GRUND, LIDIANE ZITO; LIMA, CARLA; LOPES-FERREIRA, MONICA. Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis. PLoS One, v. 12, n. 2, . (13/07467-1, 03/13751-2, 10/51130-3, 98/14307-9, 12/50001-0)
CHAPARRO, E.; DA SILVA JUNIOR, P. I.. Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, v. 48, n. 3, p. 277-285, . (13/07467-1)
PEDROSO, AURELIO; MATIOLI, SERGIO RUSSO; MURAKAMI, MARIO TYAGO; PIDDE-QUEIROZ, GISELLE; TAMBOURGI, DENISE V.. Adaptive evolution in the toxicity of a spider's venom enzymes. BMC Evolutionary Biology, v. 15, . (13/07467-1)
DA SILVA, MARCELO S.; PAVANI, RAPHAEL S.; DAMASCENO, JEZIEL D.; MARQUES, CATARINA A.; MCCULLOCH, RICHARD; ORSINI TOSI, LUIZ RICARDO; ELIAS, MARIA CAROLINA. Nuclear DNA Replication in Trypanosomatids: There Are No Easy Methods for Solving Difficult Problems. Trends in Parasitology, v. 33, n. 11, p. 858-874, . (13/07467-1, 15/10580-0, 14/24170-5, 16/50050-2)
DA SILVA, MARCELO SANTOS; MARIN MUNOZ, PAULA ANDREA; ARMELIN, HUGO AGUIRRE; ELIAS, MARIA CAROLINA. Differences in the Detection of BrdU/EdU Incorporation Assays Alter the Calculation for G1, S, and G2 Phases of the Cell Cycle in Trypanosomatids. Journal of Eukaryotic Microbiology, v. 64, n. 6, p. 756-770, . (13/07467-1, 15/10580-0, 14/24170-5)
ALVAREZ-FLORES, MILYAM P.; HEBERT, AUDREY; GOUELLE, CATHY; GELLER, SARAH; CHUDZINSKI-TAVASSI, ANA M.; PELLERIN, LUC. Neuroprotective effect of rLosac on supplement-deprived mouse cultured cortical neurons involves maintenance of monocarboxylate transporter MCT2 protein levels. Journal of Neurochemistry, v. 148, n. 1, p. 80-96, . (13/07467-1, 15/50040-4)
BENSAOUD, CHAIMA; AOUNALLAH, HAJER; SCIANI, JULIANA MOZER; FARIA, FERNANDA; CHUDZINSKI-TAVASSI, ANA MARISA; BOUATTOUR, ALI; M'GHIRBI, YOUMNA. Proteomic informed by transcriptomic for salivary glands components of the camel tick Hyalomma dromedarii. BMC Genomics, v. 20, n. 1, . (13/07467-1)
DE FREITAS, BARBARA GUIMARAES; PEREIRA, LEANDRO MARCIO; SANTA-CECILIA, FLAVIA VIANNA; HOSCH, NATALIA GABRIELE; PICOLO, GISELE; CURY, YARA; ZAMBELLI, VANESSA O.. Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia. FRONTIERS IN NEUROSCIENCE, v. 13, . (13/07467-1, 08/57898-0)
CHAPARRO-AGUIRRE, ELISA; SEGURA-RAMIREZ, PAULA J.; ALVES, FLAVIO L.; RISKE, KARIN A.; MIRANDA, ANTONIO; SILVA JUNIOR, I, PEDRO. Antimicrobial activity and mechanism of action of a novel peptide present in the ecdysis process of centipede Scolopendra subspinipes subspinipes. SCIENTIFIC REPORTS, v. 9, . (13/07467-1)
MENEZES, MILENE C.; IMBERT, LIONEL; KITANO, EDUARDO S.; VERNET, THIERRY; SERRANO, SOLANGE M. T.. Recombinant expression of the precursor of the hemorrhagic metalloproteinase HF3 and its non-catalytic domains using a cell-free synthesis system. Amino Acids, v. 48, n. 9, p. 2205-2214, . (13/07467-1)
SILVA, THAIOMARA A.; SMUCZEK, BASILIO; VALADAO, IURI C.; DZIK, LUCIANA M.; IGLESIA, REBECA P.; CRUZ, MARIO C.; ZELANIS, ANDRE; DE SIQUEIRA, ADRIANE S.; SERRANO, SOLANGE M. T.; GOLDBERG, GARY S.; et al. AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility. ONCOTARGET, v. 7, n. 31, p. 49998-50016, . (13/07467-1, 11/09472-7, 15/00544-6, 10/07699-1)
CAMPOS, POLLYANNA FERNANDES; ANDRADE-SILVA, DEBORA; ZELANIS, ANDRE; PAES LEME, ADRIANA FRANCO; TEIXEIRA ROCHA, MARISA MARIA; MENEZES, MILENE CRISTINA; SERRANO, SOLANGE M. T.; MEIRELLES JUNQUEIRA-DE-AZEVE, INACIO DE LOIOLA. Trends in the Evolution of Snake Toxins Underscored by an Integrative Omics Approach to Profile the Venom of the Colubrid Phalotris mertensi. GENOME BIOLOGY AND EVOLUTION, v. 8, n. 8, p. 2266-2287, . (13/07467-1)
JUNQUEIRA-DE-AZEVEDO, INACIO L. M.; CAMPOS, POLLYANNA F.; CHING, ANA T. C.; MACKESSY, STEPHEN P.. Colubrid Venom Composition: An -Omics Perspective. TOXINS, v. 8, n. 8, . (13/07467-1, 12/00177-5)
ANDRADE-SILVA, DEBORA; ZELANIS, ANDRE; KITANO, EDUARDO S.; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.; REIS, MARCELO S.; LOPES, ALINE S.; SERRANO, SOLANGE M. T.. Proteomic and Glycoproteomic Profilings Reveal That Post- translational Modifications of Toxins Contribute to Venom Phenotype in Snakes. JOURNAL OF PROTEOME RESEARCH, v. 15, n. 8, p. 2658-2675, . (13/07467-1, 13/13548-4)
ZELANIS, ANDRE; SILVA, DEBORA A.; KITANO, EDUARDO S.; LIBERATO, TARCISIO; FUKUSHIMA, ISABELLA; SERRANO, SOLANGE M. T.; TASHIMA, ALEXANDRE K.. A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies. Comparative Biochemistry and Physiology D-Genomics & Proteomics, v. 31, . (13/14651-3, 14/06579-3, 17/20106-9, 13/07467-1, 17/07897-7, 13/13548-4)
LIMA DINIZ, LAURA CRISTINA; MIRANDA, ANTONIO; DA SILVA, JR., PEDRO ISMAEL. Human Antimicrobial Peptide Isolated From Triatoma infestans Haemolymph, Trypanosoma cruzi-Transmitting Vector. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 8, . (13/07467-1)
GUIDOLIN, FELIPE RAIMONDI; CARICATI, CELSO PEREIRA; MARCELINO, JOSE ROBERTO; DA SILVA, WILMAR DIAS. Development of Equine IgG Antivenoms against Major Snake Groups in Mozambique. PLoS Neglected Tropical Diseases, v. 10, n. 1, . (13/07467-1)
CASTIBLANCO-VALENCIA, MONICA MARCELA; FRAGA, TATIANA RODRIGUES; PAGOTTO, ANA HELENA; DE TOLEDO SERRANO, SOLANGE MARIA; ESTIMA ABREU, PATRICIA ANTONIA; BARBOSA, ANGELA SILVA; ISAAC, LOURDES. Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion. Immunobiology, v. 221, n. 5, p. 679-689, . (13/07467-1, 10/50043-0)
LIBERATO, TARCISIO; PESSOTTI, DAYELLE S.; FUKUSHIMA, ISABELLA; KITANO, EDUARDO S.; SERRANO, SOLANGE M. T.; ZELANIS, ANDRE. Signatures of protein expression revealed by secretome analyses of cancer associated fibroblasts and melanoma cell lines. JOURNAL OF PROTEOMICS, v. 174, p. 1-8, . (13/07467-1, 15/18096-0, 14/06579-3, 17/07897-7)
CORREA, MARA A.; OKAMOTO, CINTHYA K.; GONCALVES-DE-ANDRADE, RUTE M.; VAN DEN BERG, CARMEN W.; TAMBOURGI, DENISE V.. Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. PLoS One, v. 11, n. 4, . (13/07467-1)
PACHECO, MARIO T. F.; BERRA, CAROLINA M.; MORAIS, KATIA L. P.; SCIANI, JULIANA M.; BRANCO, VANIA G.; BOSCH, ROSEMARY V.; CHUDZINSKI-TAVASSI, ANA M.. Dynein Function and Protein Clearance Changes in Tumor Cells Induced by a Kunitz-Type Molecule, Amblyomin-X. PLoS One, v. 9, n. 12, . (13/07467-1, 98/14307-9, 11/05969-4)
ZELANIS, ANDRE; HUESGEN, PITTER F.; OLIVEIRA, ANA KARINA; TASHIMA, ALEXANDRE K.; SERRANO, SOLANGE M. T.; OVERALL, CHRISTOPHER M.. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. JOURNAL OF PROTEOMICS, v. 113, p. 260-267, . (13/07467-1, 10/17328-0, 11/23403-8, 11/08514-8)
ANDRADE, GABRIELLE R.; NEW, ROGER R. C.; SANT'ANNA, OSVALDO A.; WILLIAMS, NEIL A.; ALVES, ROSELY C. B.; PIMENTA, DANIEL C.; VIGERELLI, HUGO; MELO, BRUNA S.; ROCHA, LETICIA B.; PIAZZA, ROXANE M. F.; et al. A universal polysaccharide conjugated vaccine against O111 E. coli. HUMAN VACCINES & IMMUNOTHERAPEUTICS, v. 10, n. 10, p. 2864-2874, . (13/07467-1, 12/11325-5)
DA SILVA, MARCELO SANTOS; HOVEL-MINER, GALADRIEL A.; BRIGGS, EMMA M.; ELIAS, MARIA CAROLINA; MCCULLOCH, RICHARD. Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes. PLOS PATHOGENS, v. 14, n. 11, . (13/07467-1, 14/24170-5, 17/18719-2, 16/50050-2)
ESTRELA, GUSTAVO; GUBITOSO, MARCO DIMAS; FERREIRA, CARLOS EDUARDO; BARRERA, JUNIOR; REIS, MARCELO S.. An Efficient, Parallelized Algorithm for Optimal Conditional Entropy-Based Feature Selection. Entropy, v. 22, n. 4, . (16/25959-7, 13/07467-1, 15/01587-0)
CHAVES, ALISON F. A.; CASTILHO, DANIELE G.; NAVARRO, MARINA V.; OLIVEIRA, ANA K.; SERRANO, SOLANGE M. T.; TASHIMA, ALEXANDRE K.; BATISTA, WAGNER L.. Phosphosite-specific regulation of the oxidative-stress response of Paracoccidioides brasiliensis: a shotgun phosphoproteomic analysis. Microbes and Infection, v. 19, n. 1, p. 34-46, . (14/13961-1, 11/14392-2, 13/07467-1, 12/19321-9, 12/17530-0)
MARIN, PAULA ANDREA; DA SILVA, MARCELO SANTOS; PAVANI, RAPHAEL SOUZA; MACHADO, CARLOS RENATO; ELIAS, MARIA CAROLINA. Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment. SCIENTIFIC REPORTS, v. 8, . (13/07467-1, 15/10580-0, 14/24170-5, 16/50050-2)
ZAMBELLI, VANESSA O.; PICOLO, GISELE; FERNANDES, CARLOS A. H.; FONTES, MARCOS R. M.; CURY, YARA. Secreted Phospholipases A(2) from Animal Venoms in Pain and Analgesia. TOXINS, v. 9, n. 12, . (13/07467-1, 15/01254-1, 11/17974-2)
ZAMBELLI, VANESSA O.; GROSS, ERIC R.; CHEN, CHE-HONG; GUTIERREZ, VANESSA P.; CURY, YARA; MOCHLY-ROSEN, DARIA. Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain. Science Translational Medicine, v. 6, n. 251, . (13/07467-1, 11/08873-8, 12/05035-4)
TEIXEIRA, N. B.; SANT'ANNA, M. B.; GIARDINI, A. C.; ARAUJO, L. P.; FONSECA, L. A.; BASSO, A. S.; CURY, Y.; PICOLO, G.. Crotoxin down-modulates pro-inflammatory cells and alleviates pain on the MOG(35-55)-induced experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. BRAIN BEHAVIOR AND IMMUNITY, v. 84, p. 253-268, . (11/17974-2, 10/12903-7, 13/07467-1)
ALMEIDA, MICHELLE TEIXEIRA DE; FREITAS-DE-SOUSA, LUCIANA APARECIDA; COLOMBINI, MONICA; GIMENES, SARAH N. C.; KITANO, EDUARDO S.; FAQUIM-MAURO, ELIANA L.; SERRANO, SOLANGE M. T.; MOURA-DA-SILVA, ANA MARIA. Inflammatory Reaction Induced by Two Metalloproteinases Isolated from Bothrops atrox Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components. TOXINS, v. 12, n. 2, . (13/07467-1, 16/50127-5, 14/26058-8)
NAVARRO, MARINA V.; CHAVES, ALISON F. A.; CASTILHO, DANIELE G.; CASULA, ISIS; CALADO, JULIANA C. P.; CONCEICAO, PALLOMA M.; IWAI, LEO K.; DE CASTRO, BEATRIZ F.; BATISTA, WAGNER L.. Effect of Nitrosative Stress on theS-Nitroso-Proteome ofParacoccidioides brasiliensis. FRONTIERS IN MICROBIOLOGY, v. 11, . (17/04592-0, 13/07467-1, 16/04000-3, 15/09654-9, 17/17943-6)
DA SILVA, MARCELO SANTOS; LOPES, PRISCILA HESS; ELIAS, MARIA CAROLINA; TAMBOURGI, V, DENISE. Cytotoxic and genotoxic effects on human keratinocytes triggered by sphingomyelinase D from Loxosceles venom. ARCHIVES OF TOXICOLOGY, v. 94, n. 10, . (15/17053-5, 13/07467-1, 14/24170-5)
SOARES-SCHANOSKI, ALESSANDRA; BAPTISTA CRUZ, NATALIA; DE CASTRO-JORGE, LUIZA ANTUNES; HOMEM DE CARVALHO, RENAN VILLANOVA; DOS SANTOS, CLIOMAR ALVES; DA ROS, NANCY; OLIVEIRA, URSULA; COSTA, DANUZA DUARTE; SIMOES DOS SANTOS, CECILIA LUIZA; CUNHA, MARIELTON DOS PASSOS; et al. Systems analysis of subjects acutely infected with the Chikungunya virus. PLOS PATHOGENS, v. 15, n. 6, . (12/19278-6, 13/07467-1, 15/25055-8, 13/08216-2, 16/08204-2, 17/50137-3)
TEIXEIRA, SAMUEL COTA; LOPES, DAIANA SILVA; DA SILVA, MARCELO SANTOS; CORDERO DA LUZ, FELIPE ANDRES; CIRILO GIMENES, SARAH NATALIE; BORGES, BRUNA CRISTINA; DA SILVA, ALINE ALVES; MARTINS, FLAVIA ALVES; DOS SANTOS, MARIUS ALVES; TEIXEIRA, THAISE LARA; et al. Pentachloropseudilin Impairs Angiogenesis by Disrupting the Actin Cytoskeleton, Integrin Trafficking and the Cell Cycle. CHEMBIOCHEM, v. 20, n. 18, . (13/07467-1, 14/24170-5)
AMADEU MEGALE, ANGELA ALICE; MAGNOLI, FABIO CARLOS; KUNIYOSHI, ALEXANDRE KAZUO; IWAI, LEO KEI; TAMBOURGI, DENISE V.; PORTARO, FERNANDA C. V.; DA SILVA, WILMAR DIAS. Kn-Ba: a novel serine protease isolated from Bitis arietans snake venom with fibrinogenolytic and kinin-releasing activities. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, . (13/07467-1, 13/15344-7, 15/15364-3)
SEGURA-RAMIREZ, PAULA J.; SILVA JUNIOR, PEDRO I.. Loxosceles gaucho Spider Venom: An Untapped Source of Antimicrobial Agents. TOXINS, v. 10, n. 12, . (13/07467-1)
CRISPIM, MARCELL; DAMASCENO, FLAVIA SILVA; HERNANDEZ, AGUSTINO; BARISON, MARIA JULIA; SAUTER, ISMAEL PRETTO; PAVANI, RAPHAEL SOUZA; MOURA, ALEXANDRE SANTOS; FURUSHO PRAL, ELIZABETH MIEKO; CORTEZ, MAURO; ELIAS, MARIA CAROLINA; et al. The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection. PLoS Neglected Tropical Diseases, v. 12, n. 1, . (13/07467-1, 16/06034-2, 15/10580-0, 14/10443-0, 16/50050-2)
FERREIRA JUNIOR, WILSON ALVES; ZAHARENKO, ANDRE JUNQUEIRA; KAZUMA, KOHEI; PICOLO, GISELE; GUTIERREZ, VANESSA PACCIARI; DE FREITAS, JOSE CARLOS; KONNO, KATSUHIRO; CURY, YARA. Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391. TOXINS, v. 10, n. 1, . (13/07467-1, 11/01183-6, 09/08089-5)
EMILIO TAVERNELLI, LUIS; MOTTA, MARIA CRISTINA M.; SILVA GONCALVES, CAMILA; DA SILVA, MARCELO SANTOS; ELIAS, MARIA CAROLINA; LUCIA ALONSO, VICTORIA; SERRA, ESTEBAN; CRIBB, PAMELA. Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity. SCIENTIFIC REPORTS, v. 9, . (13/07467-1, 14/24170-5)
KIMURA, LOUISE FAGGIONATO; SANT'ANNA, MORENA BRAZIL; ZAMBELLI, VANESSA OLZON; GIARDINI, ALINE CAROLINA; SILVA JARED, SIMONE GONCALVES; ANTONIAZZI, MARTA MARIA; DE MOURA MATTARAIA, VANIA GOMES; PAGANO, ROSANA LIMA; PICOLO, GISELE. Early exposure to environmental enrichment protects male rats against neuropathic pain development after nerve injury. Experimental Neurology, v. 332, . (13/07467-1, 08/57898-0, 13/20795-8)
NACHTIGALL, PEDRO G.; GRAZZIOTIN, FELIPE G.; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. MITGARD: an automated pipeline for mitochondrial genome assembly in eukaryotic species using RNA-seq data. BRIEFINGS IN BIOINFORMATICS, v. 22, n. 5, . (13/07467-1, 16/50127-5, 18/26520-4)
LIMA DINIZ, LAURA CRISTINA; SILVA JUNIOR, PEDRO ISMAEL. Hemoglobin Reassembly of Antimicrobial Fragments from the Midgut of Triatoma infestans. BIOMOLECULES, v. 10, n. 2, . (13/07467-1)
RICILUCA, K. C. T.; BORGES, A. C.; MELLO, J. F. R.; DE OLIVEIRA, U. C.; SERDAN, D. C.; FLOREZ-ARIZA, A.; CHAPARRO, E.; NISHIYAMA-JR, M. Y.; CASSAGO, A.; JUNQUEIRA-DE-AZEVEDO, I. L. M.; et al. Myriapod haemocyanin: the first three-dimensional reconstruction of Scolopendra subspinipes and preliminary structural analysis of S. viridicornis. OPEN BIOLOGY, v. 10, n. 4, . (13/07467-1, 17/15340-2)
LICHTENSTEIN, FLAVIO; IQBAL, ASIF; ALVES DE LIMA WILL, SONIA ELISABETE; BOSCH, ROSEMARY VIOLA; DEOCESANO-PEREIRA, CARLOS; GOLDFEDER, MAURICIO BARBUGIANI; CHAMMAS, ROGER; MADUREIRA TRUFEN, CARLOS EDUARDO; PEREIRA MORAIS, KATIA LUCIANO; DE SOUZA, JEAN GABRIEL; et al. Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model. SCIENTIFIC REPORTS, v. 10, n. 1, . (16/13588-4, 13/07467-1, 15/50040-4, 17/02052-9)
SCHMIDT, MARIANA COSTA BRAGA; MORAIS, KATIA L. P.; DE ALMEIDA, MAIRA ESTANISLAU SOARES; IQBAL, ASIF; GOLDFEDER, MAURICIO BARBUGIANI; CHUDZINSKI-TAVASSI, ANA MARISA. Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells. CELL ADHESION & MIGRATION, v. 14, n. 1, p. 129-138, . (13/07467-1, 15/50040-4, 14/24512-3)
BERTHOLIM, LUCIANA; CHAVES, ALISON F. A.; OLIVEIRA, ANA K.; MENEZES, MILENE C.; ASEGA, AMANDA F.; TASHIMA, ALEXANDRE K.; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.. Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins. TOXINS, v. 13, n. 11, . (11/08514-8, 20/12317-2, 11/16623-1, 13/07467-1)
MONTONI, FABIO; ANDREOTTI, DIANA ZUKAS; DOS SANTOS EICHLER, ROSANGELA APARECIDA; SANTOS, WELLINGTON DA SILVA; KISAKI, CAROLINA YUKIKO; SUEHIRO ARCOS, STEPHANIE SANTOS; LIMA, ISMAEL FEITOSA; MALTAURO SOARES, MAGNA APARECIDA; NISHIYAMA-JR, MILTON YUTAKA; NAVA-RODRIGUES, DANIEL; et al. The impact of rattlesnake venom on mice cerebellum proteomics points to synaptic inhibition and tissue damage. JOURNAL OF PROTEOMICS, v. 221, . (17/17943-6, 13/07467-1, 16/04000-3, 15/50040-4, 17/06496-9)
LOPES, FLAVIA S. R.; GIARDINI, ALINE C.; SANT'ANNA, MORENA B.; KIMURA, LOUISE F.; BUFALO, MICHELLE C.; VIGERELLI, HUGO; ZAMBELLI, VANESSA O.; PICOLO, GISELE. Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 19, p. 16-pg., . (13/07467-1)
SANTOS ROSA, JOAO GABRIEL; LIMA, CARLA; LOPES-FERREIRA, MONICA. Zebrafish Larvae Behavior Models as a Tool for Drug Screenings and Pre-Clinical Trials: A Review. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 12, p. 12-pg., . (21/08891-8, 13/07467-1)
PINTO, BRUNA FERNANDES; LOPES, PRISCILA HESS; TRUFEN, CARLOS EDUARDO MADUREIRA; CHING, ANA TUNG CHING; DE AZEVEDO, INACIO DE LOIOLA MEIRELLES JUNQUEIRA; NISHIYAMA JR, MILTON YUTAKA; POHL, PAULA CRISTIANE; TAMBOURGI, DENISE V.. Role of ErbB and IL-1 signaling pathways in the dermonecrotic lesion induced by Loxosceles sphingomyelinases D. ARCHIVES OF TOXICOLOGY, v. N/A, p. 17-pg., . (13/07467-1, 20/03718-3)
DE ALMEIDA, LAISA SILVA; NISHIYAMA-JR, MILTON YUTAKA; PEDROSO, AURELIO; COSTA-DA-SILVA, ANDRE LUIS; IOSHINO, RAFAELLA SAYURI; CAPURRO, MARGARETH LARA; SUESDEK, LINCOLN. Transcriptome profiling and Calreticulin expression in Zika virus -infected Aedes aegypti. INFECTION GENETICS AND EVOLUTION, v. 107, p. 12-pg., . (13/07467-1, 14/27172-9)
GONCALVES, MARIANA TORRENTE; SQUAIELLA-BAPTISTAO, CARLA CRISTINA; PIDDE, GISELLE; LOPES, PRISCILA HESS; DA SILVA NUNES, ISEU; TAMBOURGI, DENISE V.. P-MAPA, a Fungi-Derived Immunomodulatory Compound, Induces a Proinflammatory Response in a Human Whole Blood Model. Mediators of Inflammation, v. 2020, . (13/07467-1, 12/05306-8)
BAYONA-SERRANO, JUAN DAVID; VIALA, VINCENT LOUIS; RAUTSAW, RHETT M.; SCHRAMER, TRISTAN D.; BARROS-CARVALHO, GESIELE A.; NISHIYAMA, JR., MILTON YUTAKA; FREITAS-DE-SOUSA, LUCIANA A.; MOURA-DA-SILVA, ANA MARIA; PARKINSON, CHRISTOPHER L.; GRAZZIOTIN, FELIPE GOBBI; et al. Replacement and Parallel Simplification of Nonhomologous Proteinases Maintain Venom Phenotypes in Rear-Fanged Snakes. Molecular Biology and Evolution, v. 37, n. 12, p. 3563-3575, . (13/07467-1, 16/50127-5, 17/24546-3, 17/24498-9)
LIMA, CARLA; ANDRADE-BARROS, ALINE INGRID; CARVALHO, FABIANA FRANCO; FALCAO, MARIA ALICE PIMENTEL; LOPES-FERREIRA, MONICA. Inflammasome Coordinates Senescent Chronic Wound Induced by Thalassophryne nattereri Venom. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 24, n. 9, p. 20-pg., . (13/07467-1, 15/17160-6, 16/15157-0, 16/17620-0)
PIDDE, GISELLE; NISHIYAMA, MILTON Y.; DE OLIVEIRA, URSULA CASTRO; VILLAS-BOAS, ISADORA M.; PAES-LEME, ADRIANA F.; JUNQUEIRA-DE-AZEVEDO, INACIO L.; MARQUES-PORTO, RAFAEL; SQUAIELLA-BAPTISTAO, CARLA C.; TAMBOURGI, DENISE V.. Integrative multiomics analysis of Premolis semirufa caterpillar venom in the search for molecules leading to a joint disease. SCIENTIFIC REPORTS, v. 11, n. 1, . (13/07467-1, 15/50040-4)
RICILUCA, KATIE C. T.; OLIVEIRA, URSULA C.; MENDONCA, RONALDO Z.; BOZELLI JUNIOR, JOSE C.; SCHREIER, SHIRLEY; DA SILVA JUNIOR, PEDRO I.. Rondonin: antimicrobial properties and mechanism of action. FEBS OPEN BIO, v. 11, n. 9, SI, . (13/07467-1)
BAGATELLI, FELIPE F. M.; DE LUNA VITORINO, FRANCISCA N.; DA CUNHA, JULIA P. C.; OLIVEIRA, CARLA C.. The ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events. Nucleic Acids Research, v. 49, n. 12, p. 7053-7074, . (15/05776-2, 15/06477-9, 13/07467-1)
LIMA, CARLA; DISNER, GEONILDO RODRIGO; FALCAO, MARIA ALICE PIMENTEL; SENI-SILVA, ANA CAROLINA; MALESKI, ADOLFO LUIS ALMEIDA; SOUZA, MILENA MARCOLINO; REIS TONELLO, MAYARA CRISTINA; LOPES-FERREIRA, MONICA. The Natterin Proteins Diversity: A Review on Phylogeny, Structure, and Immune Function. TOXINS, v. 13, n. 8, . (13/07467-1, 19/27677-7, 19/02333-3)
ALMEIDA MALESKI, ADOLFO LUIS; SANTOS ROSA, JOAO GABRIEL; GONCALVES BERNARDO, JEFFERSON THIAGO; ASTRAY, RENATO MANCINI; BANDERO WALKER, CRISTIANI ISABEL; LOPES-FERREIRA, MONICA; LIMA, CARLA. Recapitulation of Retinal Damage in Zebrafish Larvae Infected with Zika Virus. CELLS, v. 11, n. 9, p. 15-pg., . (13/07467-1)
LARA, PRISCILA G.; ESTEVES, ELIANE; SALES-CAMPOS, HELIOSWILTON; ASSIS, JOSIANE B.; HENRIQUE, MARESSA O.; BARROS, MICHELE S.; NETO, LEILA S.; SILVA, PEDRO, I; MARTINS, JOILSON O.; CARDOSO, CRISTINA R. B.; et al. AeMOPE-1, a Novel Salivary Peptide From Aedes aegypti, Selectively Modulates Activation of Murine Macrophages and Ameliorates Experimental Colitis. FRONTIERS IN IMMUNOLOGY, v. 12, p. 15-pg., . (20/03175-0, 13/00740-4, 09/09892-6, 15/22934-0, 13/07467-1)
BAYONA-SERRANO, JUAN DAVID; GRAZZIOTIN, FELIPE GOBI; SALAZAR-VALENZUELA, DAVID; VALENTE, RICHARD H.; NACHTIGALL, PEDRO GABRIEL; COLOMBINI, MONICA; MOURA-DA-SILVA, ANA; JUNQUEIRA-DE-AZEVEDO, INACIO LOIOLA MEIRELLES. Independent Recruitment of Different Types of Phospholipases A2 to the Venoms of Caenophidian Snakes: The Rise of PLA(2)-IIE within Pseudoboini (Dipsadidae). Molecular Biology and Evolution, v. 40, n. 7, p. 15-pg., . (13/07467-1, 17/24498-9, 16/50127-5, 17/24546-3)
FLORENTINO, P. T. V.; VITORINO, F. N. L.; MENDES, D.; DA CUNHA, J. P. C.; MENCK, C. F. M.. Trypanosoma cruzi infection changes the chromatin proteome profile of infected human cells. JOURNAL OF PROTEOMICS, v. 272, p. 11-pg., . (13/07467-1, 19/19435-3, 17/18344-9, 13/08028-1, 18/15553-9)
CANTERO, T. M.; SILVA JUNIOR, P., I; NEGRI, G.; NASCIMENTO, R. M.; MENDONCA, R. Z.. Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica. Toxin Reviews, v. 42, n. 1, p. 16-pg., . (13/07467-1)
MENEZES, A. P. J.; SILBER, A. M.; ELIAS, M. C.; DA CUNHA, J. P. C.. Trypanosoma cruzi cell cycle progression exhibits minimal variation in histone PTMs with unique histone H4 acetylation pattern. JOURNAL OF PROTEOMICS, v. 315, p. 9-pg., . (13/07467-1, 21/12938-0, 20/00694-6, 24/14470-3, 24/02275-1, 19/21354-1, 18/14432-3, 18/15553-9)
NACHTIGALL, PEDRO G.; NYSTROM, GUNNAR S.; BROUSSARD, EMILIE M.; WRAY, KENNETH P.; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.; PARKINSON, CHRISTOPHER L.; MARGRES, MARK J.; ROKYTA, DARIN R.. A Segregating Structural Variant Defines Novel Venom Phenotypes in the Eastern Diamondback Rattlesnake. Molecular Biology and Evolution, v. 42, n. 4, p. 16-pg., . (18/26520-4, 13/07467-1, 16/50127-5, 22/04988-0)
DE SOUZA, I; MONTEIRO, L. K. S.; GUEDES, C. B.; SILVA, M. M.; ANDRADE-TOMAZ, M.; CONTIERI, B.; LATANCIA, M. T.; MENDES, D.; PORCHIA, B. F. M. M.; LAZARINI, M.; et al. High levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation. CELL DEATH & DISEASE, v. 13, n. 7, p. 13-pg., . (19/19435-3, 19/26268-6, 19/15320-7, 13/07467-1, 19/21745-0, 19/27080-0, 09/53840-0)
MATHEUS NOLASCO; DOUGLAS O. C. MARIANO; DANIEL C. PIMENTA; ILKA BIONDI; ALEXSANDRO BRANCO. Proteomic analyses of venom from a Spider Hawk, Pepsis decorata. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 29, . (13/07467-1)
DE FRANCA, FELIPE SILVA; ORSI, RICARDO DE OLIVEIRA; FERNANDES, DAYANNE CARLA; LEONEL, THYAGO BISPO; TAMBOURGI, DENISE V.. Africanized honeybee venom (Apis mellifera) promotes human complement activation split products storm. FRONTIERS IN IMMUNOLOGY, v. 15, p. 16-pg., . (13/07467-1)
MIYAMOTO, JACKSON GABRIEL; KITANO, EDUARDO SHIGUEO; ZELANIS, ANDRE; NACHTIGALL, PEDRO GABRIEL; JUNQUEIRA-DE-AZEVEDO, INACIO; SANT'ANNA, SAVIO STEFANINI; SILVA, ROGERIO LAURIA DA; BERSANETTI, PATRICIA ALESSANDRA; CARMONA, ADRIANA KARAOGLANOVIC; PEREIRA, PEDRO JOSE BARBOSA; et al. A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity. Biochimie, v. 216, p. 9-pg., . (13/07467-1, 17/21052-0, 21/05975-6, 17/20106-9)
OKAMOTO, CINTHYA KIMORI; VAN DEN BERG, CARMEN W.; POHL, PAULA C.; TAMBOURGI, DENISE V.. Role of the complement system in kidney cell death induced by Loxosceles venom Sphingomyelinases D. ARCHIVES OF TOXICOLOGY, v. 98, n. 5, p. 12-pg., . (13/07467-1)
DOS SANTOS SILVA, NORTON FELIPE; MAILHO-FONTANA, PEDRO LUIZ; DA SILVA-JUNIOR, PEDRO ISMAEL; MACHADO CUNHA DA SILVA, JOSE ROBERTO; WILLEMART, RODRIGO HIRATA. Morphology of the arthrodial membrane gland in a Neotropical harvester (Arachnida: Opiliones). ZOOLOGIA, v. 40, p. 9-pg., . (20/05158-5, 13/07467-1)
SOUSA, RONALDO N.; CAMPOS, CRISTIANO G. S.; WANG, WILLIAN; HASHIMOTO, RONALDO F.; ARMELIN, HUGO A.; REIS, MARCELO S.. Exploring Identifiability in Hybrid Models of Cell Signaling Pathways. ADVANCES IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, BSB 2023, v. 13954, p. 12-pg., . (19/24580-2, 13/07467-1, 21/04355-4, 15/22308-2, 19/21619-5)
TREVISAN-SILVA, DILZA; COSENZA-CONTRERAS, MIGUEL; OLIVEIRA, URSULA C.; DA ROS, NANCY; ANDRADE-SILVA, DEBORA; MENEZES, MILENE C.; OLIVEIRA, ANA KARINA; ROSA, JAQUELINE G.; SACHETTO, ANA T. A.; BINIOSSEK, MARTIN L.; et al. Systemic toxicity of snake venom metalloproteinases: Multi-omics analyses of kidney and blood plasma disturbances in a mouse model. International Journal of Biological Macromolecules, v. 253, p. 17-pg., . (13/07467-1, 17/23871-8, 13/13548-4, 17/00715-0)
LOPES-FERREIRA, MONICA; GRUND, LIDIANE ZITO; LIMA, CARLA. Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 20, p. 12-pg., . (98/14307-9, 12/50294-8, 08/55395-1, 13/07467-1, 03/13751-2, 04/15112-0)
ENTIAUSPE-NETO, OMAR M.; NACHTIGALL, PEDRO G.; BORGES-MARTINS, MARCIO; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.; GRAZZIOTIN, FELIPE G.. Highly conserved and extremely variable: The paradoxical pattern of toxin expression revealed by comparative venom-gland transcriptomics of Phalotris (Serpentes: Dipsadidae). Toxicon, v. 244, p. 15-pg., . (18/26520-4, 13/07467-1, 16/50127-5, 21/13671-7, 22/12660-4)
VITORINO, FRANCISCA N. DE LUNA; LEVY, MICHAELLA J.; WAILEMANN, ROSANGELA A. MANSANO; LOPES, MARIANA; SILVA, MARIANA LOTERIO; SARDIU, MIHAELA E.; GARCIA, BENJAMIN A.; MOTTA, MARIA CRISTINA MACHADO; OLIVEIRA, CARLA COLUMBANO; ARMELIN, HUGO AGUIRRE; et al. The antiproliferative effect of FGF2 in K-Ras-driven tumor cells involves modulation of rRNA and the nucleolus. Journal of Cell Science, v. 136, n. 22, p. 13-pg., . (17/18344-9, 11/22619-7, 13/07467-1, 17/06104-3, 18/15553-9, 19/17675-7)
MARIANO, DOUGLAS O.; SCIANI, JULIANA M.; ANTONIAZZI, MARTA M.; JARED, CARLOS; CONCEICAO, KATIA; PIMENTA, DANIEL C.. Quantity - but not diversity - of secreted peptides and proteins increases with age in the tree frog Pithecopus nordestinus. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 27, p. 12-pg., . (13/07467-1)
DISNER, GEONILDO RODRIGO; FERNANDES, THALES ALVES DE MELO; NISHIYAMA-JR, MILTON YUTAKA; LIMA, CARLA; WINCENT, EMMA; LOPES-FERREIRA, MONICA. TnP and AHR-CYP1A1 Signaling Crosstalk in an Injury-Induced Zebrafish Inflammation Model. PHARMACEUTICALS, v. 17, n. 9, p. 21-pg., . (21/08411-6, 13/07467-1, 19/27677-7)
FALCAO, MARIA ALICE PIMENTEL; WALKER, CRISTIANI ISABEL BANDERO; DISNER, GEONILDO RODRIGO; BATISTA-FILHO, JOAO; SOARES, AMANDA BEATRIZ SILVA; BALAN-LIMA, LETICIA; LIMA, CARLA; LOPES-FERREIRA, MONICA. Knockdown of miR-26a in zebrafish leads to impairment of the anti-inflammatory function of TnP in the control of neutrophilia. FISH & SHELLFISH IMMUNOLOGY, v. 114, p. 10-pg., . (13/07467-1)
ALVAREZ-FLORES, M. P.; GOMES, R. N.; PAZELLI, G. S.; CAMARGO, L.; SOUZA, J. G.; OLIVEIRA, D. S.; DEOCESANO-PEREIRA, C.; GOLDFEDER, M. B.; CHUDZINSKI-TAVASSI, A. M.. ANTI-INFLAMMATORY EFFECTS OF LONOMIA OBLIQUA CATERPILLAR PROTEIN RLOSAC ON MACROPHAGES AND CHONDROCYTES. OSTEOARTHRITIS AND CARTILAGE, v. 28, p. 2-pg., . (13/07467-1, 15/50040-4, 18/04467-4)
RUSSO, LILIAN C.; ARAUJO, CHRISTIANE B.; IWAI, LEO K.; FERRO, EMER S.; FORTI, FABIO L.. A Cyclin D2-derived peptide acts on specific cell cycle phases by activating ERK1/2 to cause the death of breast cancer cells. JOURNAL OF PROTEOMICS, v. 151, p. 9-pg., . (13/07467-1, 15/03983-0, 08/58264-5)
MONTE, ELISABETE R. C.; ROSSATO, CRISTIANO; LLANOS, RICARDO PARIONA; RUSSO, LILIAN C.; DE CASTRO, LEANDRO M.; GOZZO, FABIO C.; DE ARAUJO, CHRISTIANE B.; PERON, JEAN PIERRE S.; SANT'ANNA, OSVALDO AUGUSTO; FERRO, EMER S.; et al. Interferon-gamma activity is potentiated by an intracellular peptide derived from the human 19S ATPase regulatory subunit 4 of the proteasome. JOURNAL OF PROTEOMICS, v. 151, p. 9-pg., . (13/07467-1)
NOVAES, TATIANE FERNANDES; JORDAO, MAISA CAMILLO; BONACINA, CARLOS FELIPE; VERONEZI, ANDRE OSWALDO; RODRIGUES DE ARAUJO, CARLOS ARIEL; OLEGARIO, ISABEL CRISTINA; DE OLIVEIRA, DANIELE BOINA; USHAKOVA, VERANIKA; BIRBRAIR, ALEXANDER; PALACIO, DANIELLE DA COSTA; et al. COVID-19 pandemic impact on dentists in Latin America's epicenter: SAo-Paulo, Brazil. PLoS One, v. 16, n. 8, . (13/07467-1, 17/17943-6)
LUND, PEDER J.; LOPES, MARIANA; SIDOLI, SIMONE; CORADIN, MARIEL; DE LUNA VITORINO, FRANCISCA NATHALIA; CHAGAS DA CUNHA, JULIA PINHEIRO; GARCIA, BENJAMIN A.. FGF-2 induces a failure of cell cycle progression in cells harboring amplified K-Ras, revealing new insights into oncogene-induced senescence. MOLECULAR OMICS, v. 17, n. 5, p. 725-739, . (16/24881-4, 15/04867-4, 13/07467-1, 17/15835-1, 18/15553-9, 11/22619-7, 17/18344-9)
LIMA, CARLA; PIMENTEL FALCAO, MARIA ALICE; SANTOS ROSA, JOAO GABRIEL; DISNER, GEONILDO RODRIGO; LOPES-FERREIRA, MONICA. Pesticides and Their Impairing Effects on Epithelial Barrier Integrity, Dysbiosis, Disruption of the AhR Signaling Pathway and Development of Immune-Mediated Inflammatory Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 20, p. 19-pg., . (21/06084-8, 19/27677-7, 21/08891-8, 13/07467-1)
DA SILVA, WILMAR DIAS; DE ANDRADE, SONIA A.; AMADEU MEGALE, ANGELA ALICE; DE SOUZA, DANIEL ALEXANDRE; SANT'ANNA, OSVALDO AUGUSTO; MAGNOLI, FABIO CARLOS; GUIDOLIN, FELIPE RAIMONDI; GODOI, KEMILY STEPHANIE; SALADINI, LUCAS YURI; SPENCER, PATRICK JACK; et al. Antibodies as Snakebite Antivenoms: Past and Future. TOXINS, v. 14, n. 9, p. 13-pg., . (19/20832-7, 13/07467-1)
SANCHEZ-ROJAS, TITO; ESPINOZA-CULUPU, ABRAHAM; RAMIREZ, PABLO; IWAI, LEO KEI; MONTONI, FABIO; MACEDO-PRADA, DIEGO; SULCA-LOPEZ, MARCOS; DURAN, YERSON; FARFAN-LOPEZ, MARIELLA; HERENCIA, JENNIFER. Proteomic Study of Response to Copper, Cadmium, and Chrome Ion Stress in Yarrowia lipolytica Strains Isolated from Andean Mine Tailings in Peru. MICROORGANISMS, v. 10, n. 10, p. 22-pg., . (17/17943-6, 13/07467-1)
PESSOTTI, DAYELLE S.; ANDRADE-SILVA, DEBORA; SERRANO, SOLANGE M. T.; ZELANIS, ANDRE. Heterotypic signaling between dermal fibroblasts and melanoma cells induces phenotypic plasticity and proteome rearrangement in malignant cells. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1868, n. 12, p. 9-pg., . (14/06579-3, 19/07282-8, 16/16935-7, 13/07467-1)
ALMEIDA, DIEGO DANTAS; KITAJIMA, JOAO PAULO; NISHIYAMA, MILTON YUTAKA, JR.; CONDOMITTI, GEORGE WILLIAN; DE OLIVEIRA, URSULA CASTRO; SETUBAL, JOAO CARLOS; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. The complete mitochondrial genome of Bothrops jararaca (Reptilia, Serpentes, Viperidae). MITOCHONDRIAL DNA PART B-RESOURCES, v. 1, n. 1, p. 2-pg., . (13/07467-1, 13/07974-0, 12/00177-5)
SILVA, NORTON FELIPE DOS SANTOS; WILLEMART, RODRIGO HIRATA; SILVA, JOSE ROBERTO MACHADO CUNHA; DA SILVA JUNIOR, PEDRO ISMAEL. Secretion of the arthrodial membrane gland of a harvester (Arachnida: Opiliones): Antimicrobial activity. Journal of Invertebrate Pathology, v. 206, p. 4-pg., . (20/05158-5, 13/07467-1)
OLIVEIRA, ALAN SANTOS; BIANO, LAIZA SANTOS; PALMEIRA, DAVID NASCIMENTO; DE ALMEIDA, DAMIAO RABELO; LOPES-FERREIRA, MONICA; KOHLHOFF, MARKUS; SOUSA, JORDANO AUGUSTO CARVALHO; BRANDAO, GERALDO CELIO; DE OLIVEIRA E SILVA, ANA MARA; GRESPAN, RENATA; et al. Antinociceptive effect of Nephelium lappaceum L. fruit peel and the participation of nitric oxide, opioid receptors, and ATP-sensitive potassium channels. FRONTIERS IN PHARMACOLOGY, v. 14, p. 12-pg., . (13/07467-1)
TORRES-BONILLA, KRISTIAN A.; BAYONA-SERRANO, JUAN D.; SAENZ-SUAREZ, PAULA A.; ANDRADE-SILVA, DEBORA; BERNAL-BAUTISTA, MANUEL H.; SERRANO, SOLANGE M. T.; HYSLOP, STEPHEN. Venom proteomics and Duvernoy's venom gland histology of Pseudoboa neuwiedii (Neuwied's false boa; Dipsadidae, Pseudoboini). Toxicon, v. 254, p. 10-pg., . (16/16935-7, 16/50127-5, 13/07467-1, 17/24498-9)
SILVA, MAKSWELL ALMEIDA; LOPES, DAIANA SILVA; TEIXEIRA, SAMUEL COTA; CIRILO GIMENES, SARAH NATALIE; VASCONCELOS AZEVEDO, FERNANDA VAN PETTEN; POLLONI, LORENA; BORGES, BRUNA CRISTINA; DA SILVA, MARCELO SANTOS; BARBOSA, MARCELO JOSE; DE OLIVEIRA JUNIOR, ROBSON JOSE; et al. Genotoxic effects of BnSP-6, a Lys-49 phospholipase A(2) (PLA(2)) homologue from Bothrops pauloensis snake venom, on MDA-MB-231 breast cancer cells. International Journal of Biological Macromolecules, v. 118, p. 9-pg., . (13/07467-1, 14/24170-5)
LIMA, ALEX R. J.; DE ARAUJO, CHRISTIANE B.; BISPO, SALOE; PATANE, JOSE; SILBER, ARIEL M.; ELIAS, M. CAROLINA; DA CUNHA, JULIA P. C.. Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms. PLOS PATHOGENS, v. 17, n. 1, . (18/15553-9, 19/19690-3, 18/14432-3, 16/50050-2, 13/07467-1)
LOPES, PRISCILA HESS; FUKUSHIMA, CAROLINE SAYURI; SHOJI, ROSANA; BERTANI, ROGERIO; TAMBOURGI, V, DENISE. Searching for the toxic potential of Loxosceles amazonica and Loxosceles willianilsoni spiders' venoms. Toxicon, v. 191, p. 1-8, . (15/17053-5, 13/07467-1)
CARARO-LOPES, EDUARDO; DIAS, MATHEUS H.; DA SILVA, MARCELO S.; ZEIDLER, JULIANNA D.; VESSONI, ALEXANDRE T.; REIS, MARCELO S.; BOCCARDO, ENRIQUE; ARMELIN, HUGO A.. Autophagy buffers Ras-induced genotoxic stress enabling malignant transformation in keratinocytes primed by human papillomavirus. CELL DEATH & DISEASE, v. 12, n. 2, . (13/07467-1)
ANDRADE-SILVA, DEBORA; ZELANIS, ANDRE; TRAVAGLIA-CARDOSO, SILVIA R.; NISHIYAMA, JR., MILTON Y.; SERRANO, SOLANGE M. T.. Venom Profiling of the Insular Species Bothrops alcatraz: Characterization of Proteome, Glycoproteome, and N-Terminome Using Terminal Amine Isotopic Labeling of Substrates. JOURNAL OF PROTEOME RESEARCH, v. 20, n. 2, p. 1341-1358, . (13/13548-4, 16/16935-7, 13/07467-1, 13/14651-3)
NACHTIGALL, PEDRO G.; FREITAS-DE-SOUSA, LUCIANA A.; MASON, ANDREW J.; MOURA-DA-SILVA, ANA M.; GRAZZIOTIN, FELIPE G.; JUNQUEIRA-DE-AZEVEDO, INACIO L. M.. Differences in PLA(2) Constitution Distinguish the Venom of Two Endemic Brazilian Mountain Lanceheads, Bothrops cotiara and Bothrops fonsecai. TOXINS, v. 14, n. 4, p. 25-pg., . (18/26520-4, 13/07467-1, 16/50127-5)
LOPES-FERREIRA, MONICA; ALMEIDA MALESKI, ADOLFO LUIS; BALAN-LIMA, LETICIA; GONCALVES BERNARDO, JEFFERSON THIAGO; HIPOLITO, LUCAS MARQUES; SENI-SILVA, ANA CAROLINA; BATISTA-FILHO, JOAO; PIMENTEL FALCAO, MARIA ALICE; LIMA, CARLA. Impact of Pesticides on Human Health in the Last Six Years in Brazil. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v. 19, n. 6, p. 19-pg., . (13/07467-1)
LIMA, CARLA; ANDRADE-BARROS, ALINE INGRID; GONCALVES BERNARDO, JEFFERSON THIAGO; BALOGH, ENIKO; QUESNIAUX, VALERIE F.; RYFFEL, BERNHARD; LOPES-FERREIRA, MONICA. Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 23, n. 7, p. 15-pg., . (18/17413-0, 19/10500-7, 21/06084-8, 13/07467-1)
JERONIMO LIMA, ALEX RANIERI; DE SOUSA SILVA, HERBERT GUIMARAES; POUBEL, SALOE; ROSON, JULIANA NUNES; OLIVEIRA DE LIMA, LOYZE PAOLA; COSTA-SILVA, HELLIDA MARINA; GONCALVES, CAMILA SILVA; GALANTE, PEDRO A. F.; HOLETZ, FABIOLA; MOTTA, MARIA CRISTINA MACHADO M.; et al. Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci. EPIGENETICS & CHROMATIN, v. 15, n. 1, p. 16-pg., . (13/07467-1, 18/15553-9, 20/02708-4, 18/14432-3, 19/19834-5, 19/19690-3)
DE FRANCA, FELIPE SILVA; TAMBOURGI, DENISE V.. Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology. FRONTIERS IN IMMUNOLOGY, v. 14, p. 10-pg., . (13/07467-1)
OLIVEIRA, DOUGLAS SOUZA; DE SOUZA, JEAN GABRIEL; ALVAREZ-FLORES, MIRYAM PAOLA; CUNEGUNDES, PRISCILA S.; DEOCESANO-PEREIRA, CARLOS; LOBBA, ALINE MAIA; GOMES, RENATA N.; CHUDZINSKI-TAVASSI, ANA MARISA. Lonomia obliqua Venom Induces NF-kappa B Activation and a Pro-Inflammatory Profile in THP-1-Derived Macrophage. TOXINS, v. 13, n. 7, . (15/50040-4, 13/07467-1)
SILVA, G. M.; BERTO, D. H.; LIMA, C. A.; WAITMAN, K. B.; LIMA, C. F. G.; PREZOTO, B. C.; VIEIRA, M. L.; ROCHA, M. M. T.; GONCALVES, L. R. C.; ANDRADE, S. A.. Synergistic effect of serine protease inhibitors and a bothropic antivenom in reducing local hemorrhage and coagulopathy caused by Bothrops jararaca venom. Toxicon, v. 199, p. 87-93, . (17/00236-5, 13/07467-1, 17/04321-7)
BARROS, BIANCA CARLA SILVA CAMPITELLI; BARROS, DEBORA TEREZA LUCAS; BROCK, MATTHIAS; TOLEDO, MARCOS SERGIO; SERRANO, SOLANGE MARIA TOLEDO; SUZUKI, ERIKA; GHAEMMAGHAMI, AMIR M.. Secreted factors of Aspergillus fumigatus cause lung epithelial barrier disruption: A study using an air-liquid interface cell culture model. Medical Mycology, v. 63, n. 3, p. 5-pg., . (17/20214-6, 19/26693-9, 13/07467-1, 16/06285-5)
CAJADO-CARVALHO, DANIELA; MORONE, MARIANA S. L. C.; DA ROS, NANCY; SERRANO, SOLANGE M. T.. Interaction and cleavage of cell and plasma proteins by the platelet-aggregating serine protease PA-BJ of Bothrops jararaca venom. Biochimie, v. 232, p. 6-pg., . (17/19252-0, 13/07467-1)