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Integrated-omics modelling on feed efficiency in beef cattle

Grant number: 16/16214-8
Support Opportunities:Scholarships abroad - Research Internship - Master's degree
Effective date (Start): October 15, 2016
Effective date (End): April 14, 2017
Field of knowledge:Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
Principal Investigator:Heidge Fukumasu
Grantee:Francisco José de Novais
Supervisor: Mark Philip-Walter Styczynski
Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
Research place: Georgia Institute of Technology, United States  
Associated to the scholarship:15/01059-4 - Analysis in serum metabolomic associated with feed efficiency in Nellore, BP.MS

Abstract

Feed efficiency (FE) of beef cattle means to increase the beef productivity with less expenditure of feed. Our group have been working with feed efficiency in Nellore cattle for years performing the detection of molecular markers associated with the phenotype. Nowadays we are developing experiments working on multi-tissue omics and blood metabolomics on this important phenotype. Therefore, this proposal aims: (1) training on the basis of bioinformatics analysis of blood metabolome to characterize the serum profile of divergent animals selected for feed efficiency; (2) to perform network analyses using the metabolomics data and (3) to discuss and develop an integrative-omics model for FE in beef cattle. To achieve these objectives, we initiate a research collaboration with the Mark Styczynski group at Georgia Tech that have great knowledge and experience on metabolomics, systems biology, bioinformatics and statistical modelling.

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