Bioacumulation of As in tilápia (Oreochromis nilóticus): fractionation of as inorganic species

• Grant number: 16/05079-2
• Support Opportunities: Scholarships in Brazil - Master
• Start date: October 01, 2016
• End date: May 31, 2018
• Field of knowledge: Health Sciences - Pharmacy - Toxicological Analysis
• Principal Investigator: Mario Henrique Gonzalez
• Grantee: Nathalia dos Santos Ferreira
• Host Institution: Instituto de Biociências, Letras e Ciências Exatas (IBILCE). Universidade Estadual Paulista (UNESP). Campus de São José do Rio Preto. São José do Rio Preto , SP, Brazil

Abstract

The fish market has grown in recent years due to a search for healthier foods, since they have a low content of saturated fat, as well the increase in the population's purchasing power. However, despite the numerous health benefits, the fish may be exposed to toxic inorganic contaminants present in the water naturally or by human action, such as arsenic (As), which can cause bioaccumulation processes in species through the food chain. The toxic effects of As are closely related to their chemical forms and oxidation states, and in general inorganic compounds (As (III) and (V)) are more toxic than organic (eg. arsenobetaine). Thus, due to the restrictive limits of this contaminant and the accelerated growth of the fish market, this project aims to assess the processes and effects of bioaccumulation in the tilapia under controlled conditions. After bioaccumulation process, fish tissues are divided into fillet, liver, gills and stomach. Samples are decomposed using a furnace assisted by microwave radiation and the determinations carried out by an inductively coupled plasma mass spectrometry (ICP-MS). The study and optimization of lipid and protein fractionation methods of species of inorganic As (i-As) in these samples will also be subject of study in this research. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERREIRA, NATHALIA S.; OLIVEIRA, LUCIANO H. B.; AGRELLI, VITOR; DE OLIVEIRA, ALINE F.; NOGUEIRA, ANA R. A.; OLIVEIRA, ANDREA; GONZALEZ, MARIO H.. Bioaccumulation and acute toxicity of As(III) and As(V) in Nile tilapia (Oreochromis niloticus). Chemosphere, v. 217, p. 349-354, FEB 2019. (17/18531-3, 16/05079-2, 16/24868-8, 15/08873-9)

OLIVEIRA, LUCIANO H. B.; FERREIRA, NATHALIA S.; OLIVEIRA, ANDREA; NOGUEIRA, ANA RITA A.; GONZALEZ, MARIO H.. Evaluation of Distribution and Bioaccumulation of Arsenic by ICP-MS in Tilapia (Oreochromis niloticus) Cultivated in Different Environments. Journal of the Brazilian Chemical Society, v. 28, n. 12, p. 2455-2463, DEC 2017. (16/05079-2, 15/08873-9)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FERREIRA, Nathalia dos Santos. Bioaccumulation of As in tilapia (Oreochromis niloticus): fractionation of inorganic arsenic species. 2018. Master's Dissertation - Universidade Estadual Paulista (Unesp). Instituto de Biociências Letras e Ciências Exatas. São José do Rio Preto São José do Rio Preto.