Non-invasive urodynamic evaluation in man: analysis of efficacy and security of new model of urethral connector

• Grant number: 16/11830-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): October 01, 2016
• Effective date (End): July 31, 2017
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Carlos Arturo Levi Dancona
• Grantee: Natalie Lecce
• Host Institution: Hospital de Clínicas (HC). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The project aims to evaluate the efficacy and safety of a new model of the urethral connector, developed in partnership of Urology Discipline and UNICAMP Biomedical Engineering Center. It Will be selected men between 20 and 80 years old with or without urinary tract symptoms that seek the UNICAMP's urology clinic. Study participants must sign the consent form Clarified (WIC). After anamnesis and clinical examination, individuals will fill in the questionnaire of prostate symptoms (IPSS) and the questionnaire of overactive bladder (ICIQ-OAB) and will be asked to fill in the urination diary for three days. These exams are part of the protocol: urinalysis and culture, urinary tract ultrasound with measurement of detrusor, intravesical prostatic protrusion and residue after micturition. Participants will be sent to the urodynamic laboratory for performing the non-invasive urodynamics and, with bladder comfortably full, the urethral connector will be placed in the urethral meatus. After starting urination, the patient voluntarily interrupts the flow, blocking the connector output. This interruption (for a few seconds) permits the measurement of bladder pressure. The results will be analyzed with the questionnaires of symptoms and the urination diary; hoping to identify individuals with bladder outlet obstruction due to benign prostate enlargement, avoiding invasive procedures and enabling objective evaluation of the treatment.