Compounds screening with potential antiviral action against Alphaviruses and Orthobunyaviruses

• Grant number: 16/17457-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): November 01, 2016
• Effective date (End): November 20, 2019
• Field of knowledge: Biological Sciences - Microbiology
• Principal Investigator: Luiz Tadeu Moraes Figueiredo
• Grantee: Aline Lavado Tolardo
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 14/02438-6 - Studies with Bunyaviridae that produce human disease, AP.TEM
• Associated scholarship(s): 17/23004-2 - Screening of compounds with potential antiviral action against alphavirus and orthobunyavirus, BE.EP.DR

Abstract

Alphavirus and Orthobunyavirus are important arboviruses causing public health problems in Brazil, producing epidemics with great economic, social and economic losses. As there is no specific antiviral treatment for these viruses, medicaments are used to combat the symptoms and signs manifested by the disease in mild and moderate cases. This PhD research project proposes to search, in an initial step, for possible antiviral compounds against these arboviruses of great importance in Brazil.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE MELO JUNIOR, ARISTIDES BEZERRA; DE SOUZA, WILLIAM MARCIEL; ACRANI, GUSTAVO OLSZANSKI; CARVALHO, VALERIA LIMA; ROMEIRO, MARILIA FARIGNOLI; TOLARDO, ALINE LAVADO; DA SILVA, SANDRO PATROCA; CARDOSO, JEDSON FERREIRA; CHIANG, JANNIFER DE OLIVEIRA; DA SILVA GONCALVES VIANEZ JUNIOR, JOAO LIDIO; et al. Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil. INFECTION GENETICS AND EVOLUTION, v. 60, p. 71-76, JUN 2018. (16/17457-1, 14/20851-8, 17/13981-0, 12/24150-9, 14/02438-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

TOLARDO, Aline Lavado. Research on compounds with potential antiviral action for Mayaro and Oropouche viruses. 2020. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (PCARP/BC) Ribeirão Preto.