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Results of laparoscopic cholecystectomy for gallsotnes in patients over 60 years of age

Grant number: 16/15630-8
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): November 01, 2016
Effective date (End): April 30, 2019
Field of knowledge:Health Sciences - Medicine - Surgery
Principal researcher:Estela Regina Ramos Figueira
Grantee:Vítor Carminatti Romano
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Introduction: Cholecystectomy is one of the procedures requiring invasion of abdominal cavity most often performed. Surgical mortality in elective cholecystectomy is less than 0.5%, but may be increased in patients older than 60 years, especially in cases of acute cholecystitis. It has been reported the occurrence of complications in 51.4% of cases, and a mortality rate of 34.2% in patients older than 80 years who underwent urgent surgical treatment. Objective: To evaluate the results of laparoscopic cholecystectomy for lithiasis in patients older than 60 years. Methods: Five-hundred patients submitted to laparoscopic cholecystectomy for lithiasis from 2011 to 2015 will be retrospectively evaluated. We will analyze all medical records and the electronic database HCMED. The following parameters will be recorded: age, sex, skin color, weight, height, BMI, number of gestations, ECOG and Karnofsky status, hospital stay, complications of cholelithiasis, comorbidities, history of jaundice, hipocholia, choluria, fever, chills, pain, nausea and others, surgical risk, bilirubin, AST, ALT, glutamyl transferase, urea, creatinine, cholesterol, triglycerides, date of surgery, type of surgery, description of gallstones, duration of surgery, surgeon, drainage catheters, duration of surgery, vasoactive drugs, postoperative analgesia, postoperative complications, ICU stay, complications classified according Dindo et al, postoperative procedures, discharge date, date and cause of death. Statistical analysis: Comparisons between two groups will be performed using the Student t test, Mann-Whitney test or Fisher. ROC curves will analyze risk factors previously identified. The simple and multiple logistic regression analysis will be conducted to identify risk factors for postoperative complications. (AU)