Identification and characterization of spider Phoneutria nigriventer isolated venom, with chemotherapeutic effect on brain tumor cells

• Grant number: 17/05402-0
• Support Opportunities: Scholarships in Brazil - Technical Training Program - Technical Training
• Start date: May 01, 2017
• End date: April 30, 2019
• Field of knowledge: Biological Sciences - Pharmacology - General Pharmacology
• Principal Investigator: Catarina Raposo Dias Carneiro
• Grantee: Amanda Pires Bonfanti
• Host Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 15/04194-0 - Identification of new molecules with chemotherapeutic effect in human glioma and characterization of the mechanism, AP.JP

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DOS SANTOS, NATALIA BARRETO; BONFANTI, AMANDA PIRES; ALVES DA ROCHA-E-SILVA, THOMAZ AUGUSTO; DA SILVA, JR., PEDRO ISMAEL; DA CRUZ-HOFLING, MARIA ALICE; VERINAUD, LIANA; RAPOSO, CATARINA. Venom of the Phoneutria nigriventer spider alters the cell cycle, viability, and migration of cancer cells. Journal of Cellular Physiology, v. 234, n. 2, p. 1398-1415, FEB 2019. (15/04194-0, 17/05402-0, 17/16196-2, 16/15827-6)

BARRETO, NATALIA; CABALLERO, MARCUS; BONFANTI, AMANDA PIRES; PINHEIRO DE MATO, FELIPE CEZAR; MUNHOZ, JAQUELINE; DA ROCHA-E-SILVA, THOMAZ A. A.; SUTTI, RAFAEL; VITORINO-ARAUJO, JOAO LUIZ; VERINAUD, LIANA; RAPOSO, CATARINA. Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase beta 2: potential molecular entities to treat invasive brain cancer. CANCER CELL INTERNATIONAL, v. 20, n. 1, DEC 17 2020. (15/04194-0, 15/06134-4, 17/05402-0, 17/16196-2, 17/24331-7, 19/10003-3, 18/23559-7)

BONFANTI, AMANDA PIRES; BARRETO, NATALIA; MUNHOZ, JAQUELINE; CABALLERO, MARCUS; CORDEIRO, GABRIEL; ROCHA-E-SILVA, THOMAZ; SUTTI, RAFAEL; MOURA, FERNANDA; BRUNETTO, SERGIO; RAMOS, CELSO DARIO; et al. Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. SCIENTIFIC REPORTS, v. 10, n. 1, APR 3 2020. (18/03051-9, 16/15827-6, 17/05402-0, 15/06134-4, 17/16196-2, 15/04194-0, 18/23559-7)