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Development of scaffold based on furanic polyurea for tendon repair

Grant number: 17/02506-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date: June 01, 2017
End date: May 31, 2018
Field of knowledge:Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
Principal Investigator:Eliane Trovatti
Grantee:Isabela Gorla Gonçalves
Host Institution: Universidade de Araraquara (UNIARA). Associação São Bento de Ensino. Araraquara , SP, Brazil

Abstract

Health problems and accidents is growing in the last decades mainly because the lifestyle and increased average age, increasing the number of tissue injuries, such as bones, cartilage and tendom tissue injuries. The use of biomaterials for tissue repair has benefited patients and represents a hospital routine nowadays, with a large range of commercially available biomaterials, however, there is a great lack with respect to biomaterials which behavead equadely within the human/animal body leading to the need of studies and development of alternative materials. For tendom repair there is only a few number of available materials with adequate properties to recover the injuries. The purpose of this project is the development of anew polymer based on an isocyanate and a furan diamine as an alternative material for tendom repair. The idea is to study the properties of the polymer aiming to reach the minimal requirements for use in regenerative medicine, such as adequate mechanical properties, low toxicity and an adequate morphology. For such, the mechanical properties, morphology and the in vitro cytotoxicity in human cells will be tested. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TROVATTI, ELIANE; GONCALVES, ISABELA G.; CARVALHO, ANTONIO J. F.; GANDINI, ALESSANDRO. The contribution of bisfurfurylamine to the development and properties of polyureas. Polymer International, v. 69, n. 8, . (17/02506-0)