High resolution continuum source of molecular absorption spectrometry for isotopic monitoring of calcium in fortified foods, serum and urine

• Grant number: 17/20707-2
• Support Opportunities: Scholarships abroad - Research
• Start date: January 03, 2018
• End date: April 02, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Márcia Andreia Mesquita Silva da Veiga
• Grantee: Márcia Andreia Mesquita Silva da Veiga
• Host Investigator: Martin Resano Ezcaray
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Institution abroad: Universidad de Zaragoza, Spain

Abstract

Fortification of calcium in foods is intended to maintain, correct or prevent nutritional deficiencies in the specific population or group (such as the elderly, pregnant women and children), the development of procedures to evaluate shelf life and nutrient metabolism enriched in the human body are key contributions to the health and food sciences, especially in developing countries. The objective of this work is to develop a sensitive and accurate analytical method that allows the determination of 42Ca, 44Ca and 46Ca isotopes via CaF or CaI molecules by high resolution continuum source of molecular absorption spectrometry in fortified foods, serum and urine. For this, the isotopic shifts of the molecules will be evaluated, as well as the optimum instrumentation parameters: pyrolysis and vaporization curves, sample mass, amount of molecule-forming reagents and chemical modifier. This project is expected to contribute to fortification nutritional studies. It will be an innovative study, since procedures of isotopic measurements of metals via molecules by HR-CS MAS have not yet been reported. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

NAKADI, V, FLAVIO; GARDE, RAUL; DA VEIGA, MARCIA A. M. S.; CRUCES, JULIO; RESANO, MARTIN. A simple and direct atomic absorption spectrometry method for the direct determination of Hg in dried blood spots and dried urine spots prepared using various microsampling devices. Journal of Analytical Atomic Spectrometry, v. 35, n. 1, p. 136-144, JAN 1 2020. (17/20707-2)

ZANATTA, MELINA B. T.; NAKADI, V, FLAVIO; RESANO, MARTIN; DA VEIGA, MARCIA A. M. S.. Calcium isotope determination in urine samples via the monitoring of (CaF)-Ca-44 and (CaF)-Ca-40 molecules by high-resolution continuum source graphite furnace molecular absorption spectrometry. Journal of Analytical Atomic Spectrometry, v. 34, n. 11, p. 2280-2287, NOV 1 2019. (17/20707-2)