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Study of the chelator capacity of Brazilian marine sponge extracts

Grant number: 18/06809-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): June 01, 2018
Effective date (End): May 31, 2019
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Principal Investigator:Breno Pannia Espósito
Grantee:Nickolas Kavaliauska Zito
Home Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Metal ions are highly versatile species in biochemistry, with a wide variety of metals crucial to biological processes. However, the overloading of the so-called essential metals can trigger damage, often due to the fact that there are no strategies dedicated to their natural elimination. This project aims at the prospection of extracts of Brazilian marine sponges in order to obtain chelators for essential metal ions (eg iron, copper and manganese). This project is one of the activities of this group to continue the Project of Research Fellowship Abroad (FAPESP 13 / 13166-4), when the coordinator visited the University from Queensland (Australia).