The role of MMP-9, TIMP-1 and RECK in the diagnostic and prognostic of prostate cancer

• Grant number: 17/17489-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2018
• End date: July 31, 2019
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Sabrina Thalita dos Reis Faria
• Grantee: Fernando Noboru Cabral Mori
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The aim of this study is to analyze the expression profile of the biological markers MMP-9, TIMP-1, RECK in tissue samples from biopsies of patients with suspected prostate cancer (PC), to compare the expression profile among patients that the biopsy was positive and negative for this neoplasia and to analyze the expression of these markers in urine samples from these same patients, as well as to analyze these markers as possible prognostic factors for disease progression.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE MORAES, RODOLFO PACHECO; PIMENTA, RUAN; MORI, FERNANDO NOBORU CABRAL; DOS SANTOS, GABRIEL ARANTES; VIANA, NAYARA IZABEL; GUIMARAES, VANESSA RIBEIRO; DE CAMARGO, JULIANA ALVES; MOREIRA-LEITE', KATIA RAMOS; SROUGI, MIGUEL; NAHAS, WILLIAM CARLOS; et al. Tissue expression of MMP-9, TIMP-1, RECK, and miR338-3p in prostate gland: can it predict cancer?. MOLECULAR BIOLOGY RESEARCH COMMUNICATIONS, v. 10, n. 4, p. 149-156, DEC 2021. (17/17489-3)