Hydrogel liquid bandages

• Grant number: 18/20757-2
• Support Opportunities: Scholarships abroad - Research Internship - Scientific Initiation
• Start date: March 11, 2019
• End date: July 09, 2019
• Field of knowledge: Health Sciences - Pharmacy
• Principal Investigator: Priscila Gava Mazzola
• Grantee: Luiz Phellipe Pozzuto Borelli
• Supervisor: Daniel Kohane
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: Harvard University, Boston, United States
• Associated to the scholarship: 18/07549-1 - Loading and release of active agent in bacterial nanocellulose membrane for topical infections treatment, BP.IC

Abstract

Skin wounds are impairments that need careful thought when it comes to choosing the best route of treatment. Each type of injury has different needs to heal properly, including an adequate dressing. Along the past decade there have been efforts to develop new types of bandages capable of delivering the required properties for proper wound healing. One of the main focus of study is the design of thermoreversible hydrogel-based systems that are capable of drug delivery. Thermoreversibility is characterized by a liquid mixture of polymers that turns to gel state when applied in situ. The focus of this project is to develop a thermoreversible hydrogel liquid bandage loaded with terbinafine, an antifungal agent, to treat fungal skin infections. (AU)