Analysis of inspiratory muscle oxygenation responses at maximal inspiratory pressure maneuver in healthy men

• Grant number: 18/25519-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: January 01, 2019
• End date: December 31, 2019
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Aparecida Maria Catai
• Grantee: Ana Carolina Aparecida Marcondes Scalli
• Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated research grant: 16/22215-7 - Impact of inspiratory muscle training and aging on metabolic mapping, autonomic modulation, and cardiovascular, respiratory and metabolic responses, and prediction of cardiorespiratory health through wearables, AP.TEM

Abstract

Introduction: Measurement of maximal inspiratory pressure (MIP) is a frequent using in clinical practice as a way of measuring the strength of inspiratory muscles. However, despite its great use, little is known about the oxygenation responses of the inspiratory musculature in response to MIP in healthy individuals. Thus, knowledge of this response may help to better understand the metabolic changes of the inspiratory muscles generated by this maneuver in healthy men. Objective: To evaluate the external intercostal inspiratory muscle (EI) oxygenation responses during and after the MIP test in healthy youngsters. Materials and Methods: Twelve men, 20-40 years old, apparently healthy, will perform two days of evaluation of the MIP maneuver, with a minimum interval of 48 hours and a maximum of 1 week between evaluations. The EI muscle oxygenation variables will be collected by means of Near Infrared Spectroscopy (NIRS) (Oxymon Mk III, Artinis Medical Systems, Holanda), before, during and after performing the MIP maneuvers. The oxyhemoglobin (O2Hb), deoxyhemoglobin (HHb) and total hemoglobin (tHb) variables will be analyzed by means of specific statistical tests (parametric or non-parametric) according to the distribution of the data and their respective variances. It will be established p<0.05. Expected results: It is believed that it is possible to determine the behavior pattern of the studied variables (O2Hb, HHb and tHb), before, during and after the maneuver. The results of this study can helping to better understand the oxygenation of inspiratory muscle changes triggered by this maneuver.