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Evaluation of ocular surface disease in glaucoma patients and impact of ocular surface treatment on glaucoma control

Grant number: 18/16125-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2019
Effective date (End): August 31, 2019
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Mônica de Cássia Alves
Grantee:Leticia Fernandes do Nascimento
Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:14/19138-5 - Ocular tissue biobank implementation and investigation of new pathophysiological mechanisms of anterior segment eye diseases, AP.JP


Several studies have been discussing the coexistence of glaucoma and ocular surface disease. In patients undergoing topical antiglaucomatous treatment, prevalences close to 50% were found, with correlation between symptoms and amount of antiglaucomatous drugs used. Although several recent studies have pointed to the correlation of ocular surface alterations secondary to toxicity of topical antiglaucomatous medications, little attention has yet been paid to this fact in clinical practice. This study aims to evaluate the influence of ocular surface treatment in patients with glaucoma regarding adhesion to antiglaucoma treatment, control of intraocular pressure, signs and symptoms of ocular surface dysfunction and markers of inflammation of conjunctival tissue and tear.

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