Anticancer activity of the essential oil PA_MA05 isolated of the vegetable species Eugenia punicifolia

• Grant number: 18/19436-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2019
• End date: March 31, 2020
• Field of knowledge: Biological Sciences - Genetics
• Principal Investigator: Giovanna Barbarini Longato
• Grantee: Júlia Vitória de Souza Matos
• Host Institution: Universidade São Francisco (USF). Campus Bragança Paulista. Bragança Paulista , SP, Brazil

Abstract

It is a project that aims to evaluate the in vitro anticancer action of the essential oil PA_MA05 isolated from the plant species Eugenia punicifolia (Kunth) DC. Among the specific objectives to be achieved with this project, the following stand out: establishing a panel of tumoral strains of different tissues (glioma, melanoma, breast, lung, kidney, prostate, ovary, cervix, colon); evaluate the cytotoxicity of PA_MA05 essential oil in the various cell lines and evaluate the ability of this compound to inhibit cell migration and replication.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERNANDES, YAN M. L.; MATOS, JULIA V. S.; LIMA, CAROLINA A.; TARDINI, ANGELA M.; VIERA, FLAVIO A. P.; MAIA, JOSE G. S.; MONTEIRO, ODAIR S.; LONGATO, GIOVANNA B.; ROCHA, CLAUDIA Q.. Essential Oils Obtained from Aerial Eugenia punicifolia Parts: Chemical Composition and Antiproliferative Potential Evidenced through Cell Cycle Arrest. Journal of the Brazilian Chemical Society, v. 32, n. 7, p. 1381-1390, JUL 2021. (18/19436-7, 16/06137-6)