Introduction: Migraine is a neurological condition commonly associated with females, since its prevalent is greater in woman than man. However, there is no enough knowledge regarding the clinical features of migraine and musculoskeletal comorbidities in man. Objective: To verify if there is any difference between the sexes regarding the report of neck pain, neck-related disability, performance in the craniocervical flexion test and passive mobility of the upper cervical spine in patients with migraine. Methods: A sample will be consisted of sixty patients with migraine, thirty male and thirty female. The disability related to migraine will be assessed by the Migraine Disability Assessment; the presence and severity of cutaneous allodynia by the 12-item Allodynia Checklist; the disability related to the neck by the Neck Disability Index; and the presence of kinesiophobia by the Tampa Scale for Kinesiophobia. In the physical examination, the mobility of the upper cervical spine will be evaluated by the Flexion Rotation Test and the muscular performance of the deep cervical flexor muscles by the Craniocervical Flexion Test. The groups will be compared through statistical tests according to variables distribution and a level of significance of 0.05 will be adopted. Perspectives: The better understanding about the headache features, the neck pain and the neck disorder in males with migraine and the identification of the differences in relation to women, would improve the clinical management of this disease in a subgroup of patients that seems in the present moment underestimated.
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