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Anatomic positioning study of a transventicular assistance device in 3D models by computed tomography

Grant number: 19/04639-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): April 01, 2019
Effective date (End): March 31, 2020
Field of knowledge:Engineering - Biomedical Engineering - Bioengineering
Principal Investigator:Aron Jose Pazin de Andrade
Grantee:Gerson Tolentino Galvão Leite Andrade
Host Institution: Instituto Dante Pazzanese de Cardiologia (IDPC). Fundação Adib Jatene (FAJ). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
Associated research grant:13/24434-0 - Electromagnetic propeller systems for implantable artificial heart and mechanical circulatory support devices, AP.TEM


The main cause of death in the world is the cardiovascular diseases. A heart transplant is often the only form of treatment for certain severe heart diseases, restoring the normal conditions of the patient. An Artificial Heart or Ventricular Assist Device can be used in the following applications: maintaining the patient's life while waiting at a queue for a transplant (bridge to transplantatio); during clinical treatments to improve the patient's general health conditions (bridge to recovery); as the only therapy available for a given patient (destination therapy) or as a circulatory support at pre or postoperative period, with or without a blood oxygenator (temporary circulatory support). The Dante Pazzanese Institute of Cardiology (IDPC) is developing a new ventricular assist device (VAD), an implantable axial flow pump, to support the circulatory system and reduce shear stress, thrombus and blood hemolysis during transport through pump called the Transventricular Assist Device (TVAD). The TVAD will cross the left ventricle and the aortic valve, pumping blood from the ventricle directly into the aortic artery. Therefore, the external sizing of the implantable axial flow pump is highly important for its development, since it will allow to evaluate the anatomical positioning, flow input and other dimensions in which later studies can follow for example: computational simulations, constructions of prototypes and "In Vitro" tests.

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