Determination of the length of an intraventricular blood pump by means of an anatomical positioning study in models obtained by computed tomography

• Grant number: 17/01353-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): June 01, 2017
• Effective date (End): December 31, 2017
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Aron Jose Pazin de Andrade
• Grantee: Erick Matias da Silva
• Host Institution: Instituto Dante Pazzanese de Cardiologia (IDPC). Fundação Adib Jatene (FAJ). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil
• Associated research grant: 13/24434-0 - Electromagnetic propeller systems for implantable artificial heart and mechanical circulatory support devices, AP.TEM

Abstract

The main cause of death in the world are cardiovascular diseases. A heart transplant is often the only form of treatment for certain heart diseases, restoring the normal conditions of the patient. An Artificial Heart or Ventricular Assist Device can be used in the following applications: maintaining the patients life while waiting in the queue for a transplant (transplant bridge), During clinical treatments to improve the patients general health conditions (bridge to recovery), As the only therapy available for a given patient (target therapy) or as a circulatory support (in the pre or postoperative period) with or without a blood oxygenator. The Dante Pazzanese Institute of Cardiology (IDPC) is studying a new ventricular assist device (DAV), which is an implantable axial flow pump, in basic terms, consisting of a screw type impeller that turns by pushing fluid through the tube. Unlike a centrifugal pump, the fluid passing through on axial flow pump does not change direction. In the world of VAD, the axial flow pump carries blood from the left ventricle through an inlet cannula. Blood flows through the pump chamber and is pushed out through an exit cannula into the ascending aorta (the main blood vessel that supplies the body), the device is implanted into the heart or major arteries to provide hemodynamic support. Therefore, the external design of the implantable axial flow pump is a main step that allows to obtain details of anatomical positioning, flow input, dimensions in which further studies can follow as examples for tests such as computational simulations, prototype constructions and In Vitro assays.