Development of pre-sintered ZTA 80% Al2O3/20% ZrO2 composite blocks for milling in CAD/CAM system

• Grant number: 19/14798-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: October 01, 2019
• End date: July 14, 2022
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Estevam Augusto Bonfante
• Grantee: Adolfo Coelho de Oliveira Lopes
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Associated research grant: 12/19078-7 - Development and processing of Al2O3-ZrO2 translucent composite for CAD/CAM monolithic prostheses: the effect of aging on biaxial flexural strength, AP.JP

Abstract

Yttria-stabilized Tetragonal Zirconia Polycrystal (Y-TZP) is widely used in prosthodontics but shows hydrothermal instability at low temperatures due to the transformation from the metastable tetragonal phase to the monoclinic phase, which can lead to Low-Temperature Degradation (LTD), compromising the longevity of rehabilitation treatments.The present project aims to innovate with the synthesis of polycrystalline composites in the form of pre-sintered blocks of zirconia-reinforced alumina (ZTA - Zirconia-Toughened Alumina) for CAD/CAM systems used in dentistry. Such composites highlight the best characteristics of both alumina and zirconia, offering materials with improved mechanical resistance in relation to alumina and resistant to LTD. The motivation for the development of blocks arises from the data found by the candidate during his masters supported by FAPESP 2016/17793-1 BEPE - 2017/19362-0 where ZTA composite formulated at proportion 80% Al2O3 - 20% ZrO2 presented not only resistance to LTD, but also maintenance of mechanical and optical properties after aging. Thus, the present study seeks to innovate in the next step that is to develop a method to produce pre-sintered blocks of the same ZTA composite to be milled in a CAD/CAM system. The 80% Al2O3 - 20% ZrO2 ZTA will be synthesized in custom made matrices to generate CAD/CAM blocks able to be milled. The experiment is divided into two stages: 1.1) milling of 14 mm x 1mm discs (ISO 6872: 2015) to be characterized by Energy Dispersive X-ray Spectroscopy (EDS), Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD), density and optical properties; 1.2) Milling of discs for mechanical evaluation including biaxial flexural strength, Vickers indentation, fracture toughness and fractographic analysis. (AU)

Scientific publications

(14)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

LOPES, A. C. O.; COELHO, P. G.; WITEK, L.; BENALCAZAR JALKH, E. B.; GENOVA, L. A.; MONTEIRO, K. N.; CESAR, P. F.; LISBOA-FILHO, P. N.; BERGAMO, E. T. P.; RAMALHO, I. S.; et al. Microstructural, mechanical, and optical characterization of an experimental aging-resistant zirconia-toughened alumina (ZTA) composite. Dental Materials, v. 36, n. 12, p. E365-E374, DEC 2020. (16/17793-1, 17/19362-0, 18/03072-6, 12/19078-7, 19/14798-0, 19/08693-1, 19/00452-5, 16/18818-8)

BERGAMO, EDMARA T. P.; BASTOS, TIAGO M. C.; LOPES, ADOLFO C. O.; JUNIOR, EVERARDO N. S. DE ARAUJO; COELHO, PAULO G.; JALKH, ERNESTO B. BENALCAZAR; ZAHOUI, ABBAS; BONFANTE, ESTEVAM A.. Physicochemical and mechanical characterization of a fiber-reinforced composite used as frameworks of implant-supported prostheses. Dental Materials, v. 37, n. 8, p. E443-E453, AUG 2021. (12/19078-7, 18/03072-6, 16/18818-8, 19/00452-5, 19/14798-0)

DE ARAUJO-JUNIOR, EVERARDO N. S.; BERGAMO, EDMARA T. P.; CAMPOS, TIAGO M. B.; JALKH, ERNESTO B. BENALCAZAR; LOPES, ADOLFO C. O.; MONTEIRO, KELLI N.; CESAR, PAULO F.; TOGNOLO, FERNANDA C.; TANAKA, RICARDO; BONFANTE, ESTEVAM A.. Hydrothermal degradation methods affect the properties and phase transformation depth of translucent zirconia. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 112, DEC 2020. (19/08693-1, 19/14798-0, 12/19078-7, 19/00452-5, 16/18818-8, 18/03072-6)

BENALCAZAR JALKH, E. B.; BERGAMO, E. T. P.; MONTEIRO, K. N.; CESAR, P. F.; GENOVA, L. A.; LOPES, A. C. O.; LISBOA FILHO, P. N.; COELHO, P. G.; SANTOS, C. F.; BORTOLIN, F.; et al. Aging resistance of an experimental zirconia-toughened alumina composite for large span dental prostheses: Optical and mechanical characterization. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 104, APR 2020. (19/08693-1, 19/00452-5, 16/24165-7, 17/19362-0, 18/03072-6, 16/18657-4, 19/14798-0, 12/19078-7, 16/18818-8, 16/17793-1)

BERGAMO, EDMARA T. P.; LOPES, ADOLFO C. O.; CAMPOS, TIAGO M. B.; AMORIM, PEDRO HENRIQUE; COSTA, FABIO; BENALCAZAR-JALKH, ERNESTO B.; DE CARVALHO, LAURA F.; ZAHOUI, ABBAS; PIZA, MARIANA M. T.; GUTIERRES, ELIEZER; et al. Probability of survival and failure mode of endodontically treated incisors without ferrule restored with CAD/CAM fiber-reinforced composite (FRC) post-cores. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 136, p. 10-pg., 2022-10-21. (21/06730-7, 19/00452-5, 20/12874-9, 12/19078-7, 21/08018-2, 19/14798-0, 16/18818-8, 20/16500-6, 22/07157-1, 18/03072-6)

BERGAMO, EDMARA T. P.; CAMPOS, TIAGO M. B.; LOPES, ADOLFO C. O.; CARDOSO, KARINA B.; GOUVEA, MARCUS V. R.; ARAUJO-JUNIOR, EVERARDO N. S. DE; WITEK, LUKASZ; GIERTHMUEHLEN, PETRA C.; COELHO, PAULO G.; JALKH, ERNESTO B. BENALCAZAR; et al. Hydrothermal aging affects the three-dimensional fit and fatigue lifetime of zirconia abutments. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 124, DEC 2021. (18/03072-6, 19/14798-0, 19/08693-1, 19/19542-4, 12/19078-7, 20/12874-9, 19/00452-5, 16/18818-8)

BERGAMO, EDMARA T. P.; CAMPOS, TIAGO M. B.; PIZA, MARIANA M. T.; GUTIERREZ, ELIEZER; LOPES, ADOLFO C. O.; WITEK, LUKASZ; COELHO, PAULO G.; CELESTRINO, MARCOS; CARVALHO, LAURA F. DE; BENALCAZAR, ERNESTO B.; et al. Temporary materials used in prosthodontics: The effect of composition, fabrication mode, and aging on mechanical properties. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 133, p. 10-pg., 2022-07-12. (20/12874-9, 20/16500-6, 21/06730-7, 19/08693-1, 22/07157-1, 21/08018-2, 19/14798-0, 16/18818-8)

PIZA, MARIANA M. T.; BERGAMO, EDMARA T. P.; CAMPOS, TIAGO M. B.; CARVALHO, LAURA F.; GOULART, CELSO A.; GUTIERRES, ELIEZER; LOPES, ADOLFO C. O.; JALKH, ERNESTO B. BENALCAZAR; BONFANTE, ESTEVAM A.. Alumina-toughened zirconia nanocomposite: Aging effect on microstructural, optical, and mechanical properties. Dental Materials, v. 39, n. 11, p. 10-pg., 2023-10-14. (12/19078-7, 19/14798-0, 16/18818-8, 21/08018-2, 20/12874-9, 19/08693-1, 22/07157-1)

BERGAMO, EDMARA T. P.; YAMAGUCHI, SATOSHI; LOPES, ADOLFO C. O.; COELHO, PAULO G.; DE ARAUJO-JUNIOR, EVERARDO N. S.; JALKH, ERNESTO B. BENALCAZAR; ZAHOUI, ABBAS; BONFANTE, ESTEVAM A.. Performance of crowns cemented on a fiber-reinforced composite framework 5-unit implant-supported prostheses: in silico and fatigue analyses. Dental Materials, v. 37, n. 12, p. 1783-1793, DEC 2021. (19/08693-1, 19/00452-5, 19/14798-0, 18/03072-6)

RAMALHO, ILANA S.; BERGAMO, EDMARA T. P.; WITEK, LUKASZ; COELHO, PAULO G.; LOPES, ADOLFO C. O.; BONFANTE, ESTEVAM A.. Implant-abutment fit influences the mechanical performance of single-crown prostheses. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 102, FEB 2020. (12/19078-7, 19/14798-0, 16/17793-1, 19/08693-1, 16/18818-8)

RAMALHO, ILANA; WITEK, LUKASZ; COELHO, PAULO G.; BERGAMO, EDMARA; PEGORARO, LUIZ FERNANDO; BONFANTE, ESTEVAM A.. Influence of Abutment Fabrication Method on 3D Fit at the Implant-Abutment Connection. International Journal of Prosthodontics, v. 33, n. 6, p. 641-647, NOV-DEC 2020. (17/19362-0, 19/08693-1, 16/18818-8, 12/19078-7, 19/14798-0, 16/17793-1)

BERGAMO, EDMARA T. P.; DE ARAUJO-JUNIOR, EVERARDO N. S.; LOPES, ADOLFO C. O.; COELHO, PAULO G.; ZAHOUI, ABBAS; BENALCAZAR JALKH, ERNESTO B.; BONFANTE, ESTEVAM A.. Failure Modes and Survival of Anterior Crowns Supported by Narrow Implant Systems. BIOMED RESEARCH INTERNATIONAL, v. 2020, p. 11-pg., 2020-09-08. (12/19078-7, 16/18818-8, 19/08693-1, 19/00452-5, 18/03072-6, 19/14798-0)

LOPES, ADOLFO C. O.; BENALCAZAR-JALKH, ERNESTO B.; BERGAMO, EDMARA T. P.; CAMPOS, TIAGO M. B.; DE CARVALHO, LAURA F.; TANAKA, RICARDO; GENOVA, LUIS A.; YAMAGUCHI, SATOSHI; WITEK, LUKASZ; COELHO, PAULO G.; et al. Development of ZTA (80% Al2O3/20% ZrO2) pre-sintered blocks for milling in CAD/CAM systems. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, v. 154, p. 9-pg., 2024-04-09. (22/05496-3, 21/06730-7, 12/19078-7, 19/14798-0, 22/07157-1, 20/12874-9, 19/08693-1, 22/05495-7, 21/08018-2)

STRAZZI-SAHYON, HENRICO B.; BERGAMO, EDMARA T. P.; GIERTHMUEHLEN, PETRA C.; LOPES, ADOLFO C. O.; ALVES, LARISSA M. M.; JALKH, ERNESTO B. BENALCAZAR; ZAHOUI, ABBAS; COELHO, PAULO G.; DE CARVALHO, ALEXANDRE M.; BONFANTE, ESTEVAM A.. In vitro assessment of the effect of luting agents, abutment height, and fatigue on the retention of zirconia crowns luted to titanium base implant abutments. JOURNAL OF PROSTHETIC DENTISTRY, v. 130, n. 5, p. 8-pg., 2023-11-10. (21/07440-2, 21/06730-7, 12/19078-7, 19/14798-0, 16/18818-8, 19/08693-1, 22/12118-5, 22/07157-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LOPES, Adolfo Coelho de Oliveira. Development of pre-sintered ZTA 80% Al2O3/20% ZrO2 composite blocks for milling in CAD/CAM system. 2023. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Odontologia de Bauru (FOB/SDB) Bauru.