Changes in functional status during exacerbation of COPD

• Grant number: 19/10744-3
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: March 01, 2020
• End date: August 31, 2020
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Ercy Mara Cipulo Ramos
• Grantee: Fabiano Francisco de Lima
• Supervisor: Chris Burtin
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
• Institution abroad: Hasselt University, Diepenbeek, Belgium
• Associated to the scholarship: 18/04871-0 - EFFECTS OF THE INCLUSION OF A FUNCTIONAL CIRCUIT TO AEROBIC AND RESISTANCE TRAINING ON PHYSICAL ACTIVITY IN DAILY LIFE AND FUNCTIONALITY OF PATIENTS WITH COPD: A RANDOMIZED CLINICAL TRIAL WITH FOLLOW-UP, BP.DR

Abstract

Introduction: Exacerbations are one of the characteristics of Chronic obstructive pulmonary disease (COPD) that can lead to hospitalizations. Simple functional screening tests during hospital stay might enable us to quantify the impact of a hospitalization on functional status and to identify patients at risk for repeated exacerbations. Objective: Investigate the influence of acute exacerbations of COPD on functional status. Methods: This study will consist of a cross-sectional part and a longitudinal part which are interrelated. A convenience sample of 100 stable patients and 100 patients admitted for an acute exacerbation (not included in the stable sample) will be enrolled. Will be assessed functional status tests (short physical performance battery), functional exercise capacity (six-minute walk distance), muscle function (hand-held dynamometer), Daily physical activity (Actigraph GT3X) and pulmonary function (spirometry) Implications: The results of the study may explain more about the relationship of exacerbations, hospitalization and impact on the functional status of patients with COPD. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE BRANDT, JANA; DERAVE, WIM; VANDENABEELE, FRANK; POMIES, PASCAL; BLANCQUAERT, LAURA; KEYTSMAN, CHARLY; BARUSSO-GRUNINGER, MARINA S.; DE LIMA, FABIANO F.; HAYOT, MAURICE; SPRUIT, MARTIJN A.; et al. Efficacy of 12 weeks oral beta-alanine supplementation in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled trial. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, v. 13, n. 5, p. 12-pg., 2022-08-17. (19/10744-3)

QUADFLIEG, KIRSTEN; MACHADO, ANA; DE LIMA, FABIANO FRANCISCO; DEDEREN, ANAND; DAENEN, MARC; RUTTENS, DAVID; THOMEER, MICHIEL; SPRUIT, MARTIJN A.; BURTIN, CHRIS. Physical status, symptoms and health-related quality of life during a severe exacerbation of COPD: Recovery and discriminative capacity for future events. RESPIRATORY MEDICINE, v. 220, p. 7-pg., 2023-11-04. (19/10744-3)