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Comparation of sedatives and cardiorespiratory effects of gabapentin and butorphanol in cats

Grant number: 19/18842-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): January 01, 2020
Effective date (End): September 30, 2020
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal researcher:Aline Magalhães Ambrósio
Grantee:Luana Morais de Almeida
Home Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Cats have been increasingly present in the veterinary routine, the number of domiciled cats has been growing worldwide, however, these animals still do not receive treatments as often as dogs, that's for being aggressive when submitted to veterinary procedures. At the same time, we have a growing demand for blood transfusions, blood collection and diagnostic imaging for emergencies and perioperative procedures. In this context, we aim to explore ways to reduce stress in felines safely and efficiently in blood collection to blood transfusions and other exams such as diagnostic imaging through the use of butorphanol and gabapentin, comparing their sedative and cardiorespiratory effects. There will be 14 animals divided in em 2 groups, where the group Butorphanol will receive 0,4 mg/Kg of butorphanol intramuscular and 30 mg/Kg of physiological solution orally, while the Gabapentin group will receive 30 mg/Kg of gabapentin by mouth and 0,4 mg/Kg of physiological solution intramuscular. The sedative effects will be measured through the Feline Stress Score (KESSLER & TURNER, 1997) and the Global Sedation Score (HOPFENSPERGER, 2013). The cardiorespiratory effects will be evaluated by the sistolic, mean and diastolic arterial pressure, heart rate, respiratory rate, mucous membranes and capillary refill time. (AU)