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Evaluation of the adjuvant analgesic effect of systemic laser (ILIB) on postoperative pain

Grant number: 20/11814-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2021
Effective date (End): January 31, 2022
Field of knowledge:Health Sciences - Dentistry - Periodontology
Principal Investigator:Ana Lucia Pompeia Fraga de Almeida
Grantee:Bianca Tavares Rangel
Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil


Cleft lip and clept palate are the most common facial malformations, they result in aesthetic and functional implications that is related to occlusion, functioning of the velopharyngeal mechanism and the ear. Cleft lip and cleft palate represent a greater rehabilitation challenge and mobilize a more extensive treatment protocol. The Secondary bone alveolar graft surgery it is part of this protocol, that is ideally performed before the eruption of permanent canines. It is an extensive surgery that causes pain and edema. These post-operative conditions can be alleviated from the properties of low-intensity laser, being ILIB (Intravascular laser irradiation of blood), which is a safe and efficient method that has been used in Russia, China and Iran for over 20 years. The aim of this study is to evaluate the analgesic effect of systemic laser in patients undergoing secondary bone alveolar graft surgery. The sample will consist of 30 individuals with cleft lip and cleft palate from 9 to 15 years old, of both genders who need secondary alveolar bone graft, divided into two groups: group 1 (control) - alveolar bone graft in the area of the cleft alveolar ridge ; group 2 (ILIB) - bone graft with systemic laser application (Therapy EC at wavelength in the red spectrum 660 nm ± 10 nm, with a useful power of 100 mW ± 20%). The ILIB will be applied through a specific bracelet, on the patient's wrist, for 30 minutes, at the following times: T0ILIB- immediate postoperative period; T1ILIB - 24 hours after surgery. Postoperative pain will be assessed based on the patients' subjective responses using a Visual Analogue Scale at T1EA - 24 hours postoperatively and T2EA - 48 hours postoperatively.

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