Sedentary behavior in programs of cardiovascular rehabilitation: relationship with occurrence of signs and symptoms and biochemical profile

• Grant number: 20/08178-7
• Support Opportunities: Scholarships in Brazil - Master
• Start date: June 01, 2021
• End date: February 28, 2022
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Luiz Carlos Marques Vanderlei
• Grantee: João Pedro Lucas Neves Silva
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

Introduction: Physical exercises performed in Cardiovascular Rehabilitation Programs (CRP) can promote several benefits, however during its execution there is a greater probability of the occurrence of signs and symptoms (SS). In this perspective, it is important to identify factors that can predict the risk of SS occurrence during a CRP session. Sedentary behavior (SB) is associated with an increased risk of developing cardiovascular diseases and negative changes in the individual's biochemical profile and, in this context, may be important for this identification. Objectives: 1) to verify the presence of SB in patients attending CRP and to evaluate its correlation with the occurrence of SS in these programs; 2) to evaluate the correlation between SB with the biochemical profile (TNF-alpha, IL-6 and IL-10, fasting blood glucose, glycated hemoglobin, triglycerides, HDL, LDL and total cholesterol) of patients attending CRP. Methods: 65 patients treated at a CRP will be evaluated. Initially, the medical records of each patient for population characterization will be analyzed and the SB level assessed using an accelerometer for a period of 7 days. After this period, the SB will also be assessed using the modified LASA - SBQ questionnaire for the elderly and reports of average time spent sitting per day during the week and at the weekend. Next, patients will perform a blood collection to measure biochemical markers. In the second phase of the protocol, patients will be followed up for 24 sessions during the CRP routines to analyze and record the occurrence of SS. For data analysis, the relationships between SB with the occurrence of SS and biochemical variables will be made by Pearson or Spearman correlations, depending on the normality of the data (Shapiro-Wilk test). In the case of significant correlations, linear regression will be performed on the model without adjustment and adjusted for sex, age, use of medication to control glycemic and / or lipid levels, body mass index, abdominal circumference, socioeconomic level and weekly time of physical activity moderate to vigorous intensity. All results will be discussed at the 5% significance level.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SILVA, João Pedro Lucas Neves. Sedentary behavior in participants of a cardiac rehabilitation program: relationship with occurrence of signs and symptoms, biochemical profile and body composition. 2022. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente Presidente Prudente.