Sedentary behavior in participants of a cardiac rehabilitation program: relationship with occurrence of signs and symptoms, biochemical profile and body composition

Author(s)

João Pedro Lucas Neves Silva

• Document type: Master's Dissertation
• Press: Presidente Prudente. 2022-03-17.
• Institution: Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente
• Defense date: 2022-03-08
• Advisor: Luiz Carlos Marques Vanderlei

Abstract

Background: Physical exercises performed in Cardiac Rehabilitation Programs (CRP) can promote benefits, however during their execution there is a greater probability of signs and symptoms (SS). In this perspective, it becomes important to identify factors that can predict or risk the occurrence of SS during a CRP session. Sedentary behavior (SB) is associated with an increased risk of developing cardiovascular diseases and negative changes in the inflammatory biochemical profile (IBP) and body composition (BC) of the individual and, in this context, it may be important for this identification. Aim: 1) to evaluate the relationship between SB with the occurrence of SS in a CRP. 2) to evaluate the relationship between SB and the IBP (TNF-alpha, IL-6 and IL-10) and BC (weight and percentage of fat body weight, lean mass weight and total body water) of patients who attend CRP. Methods: There were 65 patients treated in a CRP. Initially, the medical record of each patient was detailed for the characterization evaluated and the SB level was evaluated through the use of the accelerometer for a period of 7 days. After this period, and also evaluated through the time of SB per LASA – SBQ modified for the elderly, average spent per day during the week. Then, a blood collection was performed to measure the biochemical markers and evaluated as BC using bioimpedance. In the second phase of the protocol, patients were followed up for 24 sessions during the CRP routines for analysis and recording of the occurrence of SS. For data analysis, such as relationships between SB with the occurrence of SS, biochemical variables and BC were made by Spearman or Pearson correlations, according to the normality of the data (Shapiro-Wilk test). All results were discussed at a level of less than 5% significance. Results: It is possible to observe positive correlations between SB assessed by the accelerometer and symptoms (r = 0.336; p = 0.020), and the SB assessed by the report of sitting time with the total SS (r = 0.296; p = 0.036), and correlation negative difference between the break in SB and symptoms (r = -0.361; p = 0.012). When evaluating the SB and SS relationship according to sex, positive correlations were observed only for females (p<0.05). There were no significant correlations between SB and its break with IBP and BC (p>0.05). Absence of significant correlations remained when analyzing whether the changes that occurred in the SB and in its breakdown were correlated with those obtained for the IBP and BC with the development of the program. Conclusion: The higher the SB, the greater the presence of SS observed in patients enrolled in a CRP. On the other hand, the higher the SB break, the lower the presence of SS. In terms of profiles, the SB and its breakdown did not present relationships with the IBP and BC. There were also no relationships between the 13 changes in the SB and its breakage after 6 months of performing the PRC with those observed for the IBP and BC. Information of this nature demonstrates the importance of encouraging the approach to the breakdown of SB in health education programs, in order to reduce the negative influences of this routine behavior, cardiovascular health, and consequently favor the prognosis and quality of life. (AU)

• FAPESP's process: 20/08178-7 - Sedentary behavior in programs of cardiovascular rehabilitation: relationship with occurrence of signs and symptoms and biochemical profile
• Grantee: João Pedro Lucas Neves Silva
• Support Opportunities: Scholarships in Brazil - Master