Preparation of industrially important isocyanates and polyols from CO2 and molecular platforms obtained from biomass and their use in the synthesis of polyurethanes

• Grant number: 21/06549-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: October 01, 2021
• End date: December 31, 2024
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Antonio Carlos Bender Burtoloso
• Grantee: Jorge Andrés Mora Vargas
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
• Company: Universidade de São Paulo (USP). Escola Politécnica (EP)
• Associated research grant: 20/15230-5 - Research Centre for Greenhouse Gas Innovation - RCG2I, AP.PCPE

Abstract

Polyurethanes (PUs) are one of the most important types of polymeric materials due to their applications in different fields of industrial chemistry because of their properties. Their main way of obtaining it is trough polyaddition reaction of isocyanates and polyols. The isocyanate monomers that are used as starting material are synthesized from toxic phosgene, therefore, several greener synthetic routes are being developed. Here, we will propose the synthesis of new and known isocyanates substituting phosgene for carbon dioxide (CO2) as a renewable source of C=O and using primary amines, which can be obtained from important molecular platforms synthesized from biomass. In this step, several guanidines will be used as CO2 sequestrants and activators. These catalysts are an alternative to replace conventional catalysts based on transition metals, which are sometimes expensive. On the other hand, new and known polyols will be synthetized from molecular platforms obtained from biomass, such as, ethyl acetate, succinic and levulinic acids. Both, isocyanates and polyols will be used as starting materials for the synthesis of important PUs by polyaddition reaction. (AU)

Scientific publications

(4)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

VARGAS, JORGE ANDRES MORA; MANDREKAR, KETAN S.; ECHEMENDIA, RADELL; BURTOLOSO, ANTONIO C. B.. Innovations in isocyanate synthesis for a sustainable future. ORGANIC & BIOMOLECULAR CHEMISTRY, v. N/A, p. 19-pg., 2024-11-11. (20/15230-5, 19/12300-5, 22/09140-9, 20/07147-0, 21/06549-0)

MORA VARGAS, JORGE ANDRES; RIBEIRO DA SILVA, JESSICA; LANCAROVICI ALVES, ANA CLARA; GOMEZ HIGUITA, GERMAN DARIO; CARVALHO, ANTONIO JOSE FELIX; BURTOLOSO, ANTONIO C. B.. Novel Sulfur-Containing Polyurethanes using 5-(Chloromethyl)Furfural as a Renewable Building Block. CHEMSUSCHEM, v. N/A, p. 10-pg., 2025-08-07. (21/06549-0, 20/15230-5, 23/08708-4, 20/07147-0)

DE SOUZA, JOAO H.; VARGAS, JORGE A. M.; BURTOLOSO, ANTONIO C. B.. An Improved Protocol for the Synthesis of Carbonyl Sulfoxonium Ylides. SYNTHESIS-STUTTGART, v. 56, n. 05, p. 5-pg., 2024-01-18. (20/15230-5, 21/06549-0)

VARGAS, JORGE ANDRES MORA; BURTOLOSO, ANTONIO C. B.. CO₂-Based Carbamate Synthesis Utilizing Reusable Polymer-Supported DBU. CHEMSUSCHEM, v. N/A, p. 9-pg., 2023-09-27. (21/06549-0, 20/07147-0, 20/15230-5)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

VARGAS, Jorge Andrés Mora. Synthesis of alkylcarbamates, polyurethanes, and sulfur ylides from biomass-derived molecular platformserentes produtos de alto valor agregado. 2025. Doctoral Thesis - Universidade de São Paulo (USP). Instituto de Química de São Carlos (IQSC/BT) São Carlos.