Randomized clinical trials on the efficacy of dentin desensitizing agents: compliance with CONSORT guidelines and mapping of study characteristics: a systematic review

• Grant number: 21/10826-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2021
• End date: June 30, 2022
• Field of knowledge: Health Sciences - Dentistry - Dental Clinics
• Principal Investigator: Taciana Marco Ferraz Caneppele
• Grantee: Beatriz de Souza Carreira
• Host Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Estadual Paulista (UNESP). Campus de São José dos Campos. São José dos Campos , SP, Brazil

Abstract

This systematic review aims to assess the available literature regarding the compliance of randomized clinical trials on the efficacy of dentin desensitizing agents with the CONSORT statement. In addition, the risk of bias of these same studies will be evaluated through the criteria of The Risk Of Bias tool 2.0 (ROB 2.0) of the Cochrane Collaboration. A mapping of these studies will also be carried out concerning their characteristics, such as the type of intervention studied, sensitivity assessment methods, scales used, and treatment follow-up time. A review of randomized clinical trials will be carried out. A search strategy on the subject will be drawn up in the following databases: MEDLINE via PubMed, Scopus, Web of Science, LILACS, Brazilian Dental Library (BBO), and EMBASE. Manual searches will also be performed. The analysis and data collection will be performed by two independent reviewers who will select the potential studies firstly by title and abstract and then complete reading of the selected ones. The articles will be evaluated for conformity to CONSORT on a scale: 0 = no description, 1 = deficient description and 2 = adequate description, for each item. Descriptive analyzes of the characteristics of the studies will also be carried out. (AU)