A novel ceramic-like titanium antimicrobial surface

• Grant number: 21/11771-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: February 01, 2022
• End date: December 31, 2022
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Cássio Do Nascimento
• Grantee: Marcos Miguel Ito
• Host Institution: Faculdade de Odontologia de Ribeirão Preto (FORP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Implantable materials based on titanium (Ti) or Ti alloys have been widely used in medical and dental care due to favorable mechanical properties and biocompatibility. However, when compared to ceramics, Ti surfaces are more susceptible to bacterial adhesion and colonization by periodontopathogenic species. Peri-implant infections are a major cause of implant failure and the development of implantable materials with good mechanical properties that are effective in minimizing bacterial colonization is still a challenge. Plasma electrolytic oxidation (PEO) is a simple technique for creating porous ceramic coatings of high durability and stability on Ti surfaces. Modifying the method by incorporating metals with antimicrobial effects may contribute to minimizing microorganism adhesion on Ti. The objective of this study is to develop a novel zirconia-coated Ti surface using PEO, and compare its oral biofilm formation and composition with machined or commercially double acid etched Ti surfaces in situ. Surfaces characterization will be performed by means of x-ray photoelectron spectroscopy (XPS), energy dispersive x-ray spectroscopy (EDX), laser confocal microscopy, and surface tension/wettability analyses.(AU)