Effect of Crispr-Cas9-induced mutations in the Aire gene on transcriptional, post-transcriptional activity of mTEC cells and their function on thymocyte migration

• Grant number: 22/01801-6
• Support Opportunities: Scholarships in Brazil - Technical Training Program - Technical Training
• Effective date (Start): April 01, 2022
• Effective date (End): December 31, 2022
• Field of knowledge: Biological Sciences - Immunology - Immunogenetics
• Principal Investigator: Geraldo Aleixo da Silva Passos Júnior
• Grantee: Letícia Agrelli de Brito
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 17/10780-4 - Effect of CRISPR-Cas9-induced mutations in the Aire gene (APS1 syndrome) on protein conformation, mTEC cell transcriptome and their interaction with thymocytes, AP.TEM