Clavien-Dindo vs. Comprehensive Complication Index in the evaluation of postoperative complications in elderly people undergoing percutaneous nephrolithotripsy: a retrospective study

• Grant number: 23/13960-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2023
• End date: November 30, 2025
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Alexandre Danilovic
• Grantee: Gustavo Monteiro Perrone de Oliveira
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Percutaneous nephrolithotripsy (PCNL) is the standard treatment for complex kidney stones, but it can have serious complications. The Clavien-Dindo Classification helps to evaluate those. However, it simplifies by considering only the most serious. The Comprehensive Complication Index (CCI) was developed to address this limitation by providing an index that assesses multiple complications. Nevertheless, before we adopt it as a substitute, it is important to determine whether CCI has a greater impact on postoperative prediction. Elderly patients are more prone to develop serious postoperative complications, therefore this population is ideal to compare these two classifications. To this end, we will carry out a retrospective study with patients over 60 years of age who underwent PCNL between 2009 and 2020 at the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. We will collect demographic information, medical history, surgical time, and complications from these patients based on medical records. We will apply the Clavien-Dindo Classification and the CCI to these complications, with the aim of evaluating whether there is a difference in correlation between them in relation to length of stay and visits to the emergency room. Additionally, we will evaluate which variables may be associated with the severity and multiplicity of complications.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DANILOVIC, ALEXANDRE; PERRONE, GUSTAVO; DIAS, LUCAS; MARCHINI, GIOVANNI; TORRICELLI, FABIO; BATAGELLO, CARLOS; VICENTINI, FABIO; NAHAS, WILLIAM C.; MAZZUCCHI, EDUARDO. Is it worth using the Comprehensive Complication Index over the Clavien-Dindo classification in elderly patients who underwent percutaneous nephrolithotomy?. World Journal of Urology, v. 42, n. 1, p. 8-pg., 2024-10-28. (23/13960-4)