Entomoepidemiology of Chagas disease in Amazon border regions (Brazil-Bolivia and Brazil-Peru): diversity, molecular tracking of Trypanosoma cruzi and analysis of food sources of vector insects

• Grant number: 23/09822-5
• Support Opportunities: Scholarships in Brazil - Support Program for Fixating Young Doctors
• Start date: August 01, 2023
• End date: November 24, 2024
• Field of knowledge: Biological Sciences - Parasitology - Entomology and Malacology of Parasites and Vectors
• Agreement: CNPq
• Principal Investigator: João Aristeu da Rosa
• Grantee: Vinícius Fernandes de Paiva
• Host Institution: Faculdade de Ciências Farmacêuticas (FCFAR). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated research grant: 23/01548-1 - Entomoepidemiology of Chagas disease in Amazon border regions (Brazil-Bolivia and Brazil-Peru): diversity, molecular tracking of Trypanosoma cruzi and analysis of food sources of vector insects, AP.R

Abstract

Chagas disease is a neglected disease caused by Trypanosoma cruzi that affects about eight million people worldwide. Vectorial transmission, through contact with the urine/feces of triatomines infected by the protozoan, is considered the main route of contamination. About 67 species of triatomines are present in Brazil, with at least 30 species reported in the Amazon region. Several states that make up the Brazilian Amazon (also known as the Legal Amazon) border other countries. Among them, Acre and Amazonas form the border between Brazil-Peru and Acre, Rondônia and Mato Grosso between Brazil-Bolivia. Given the diversity of triatomine species found in the legal Amazon [represented, in this proposal, by the states of Acre (11 species) and Rondônia (seven species)], as well as in Peru (18 species) and Bolivia (at least 15 species), an epidemiological alert is installed, as most species are considered potential vectors of T. cruzi. Given this and, above all, the little entomoepidemiological knowledge of the disease in the Amazonian border regions, the present project aims to analyze the diversity and food source(s) of the entomofauna of Triatominae, as well as to carry out a tracking molecular analysis of T. cruzi genotypes present in these insect vectors.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE PAIVA, VINICIUS FERNANDES; GALVAO, CLEBER; DE OLIVEIRA, JADER. Revisiting the taxonomy and geographic distribution of the subspecies Triatoma protracta woodi Usinger, 1939 (Hemiptera: Triatominae). JOURNAL OF VECTOR ECOLOGY, v. 49, n. 2, p. 2-pg., 2024-12-01. (23/09822-5)

BELINTANI, TIAGO; DE OLIVEIRA, JADER; DE PAIVA, VINICIUS FERNANDES; SANTANA, JOCIEL KLLEYTON SANTOS; FERNANDES, ISABELLA MAXWELL PAULINO; GOMES, JONATHAN SILVESTRE; HOPPE, ESTEVAM GUILHERME LUX; DA ROSA, JOAO ARISTEU. Triatomines in the city: A study of Rhodnius neglectus in Jaboticabal, São Paulo, Brazil, and its epidemiological implications. Revista da Sociedade Brasileira de Medicina Tropical, v. 57, p. 11-pg., 2024-01-01. (23/00423-0, 23/15240-9, 23/09822-5, 19/02145-2)