VIABILITY OF THE PHYSICAL-CHEMICAL PROPERTIES OF AN EXPERIMENTAL CEMENT BASED ON COPAÍBA (Copaifera multijulga Hayne) FOR PROVISIONAL INDIRECT RESTORATIONS

• Grant number: 23/07364-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: August 01, 2024
• End date: July 31, 2026
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Daniela Micheline dos Santos
• Grantee: Cássia Cunha de Lima
• Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

Eugenol, present in the composition of temporary dental cements, can be cytotoxic and interfere with the polymerization of resinous materials. To replace this component, copaiba oil (Copaifera multijuga) and white rosin (Protium heptaphyllum), herbal medicines with recognized antimicrobial and anti-inflammatory properties, may be a promising alternative. Therefore, the objective of this study is to evaluate the feasibility of the physicochemical properties of an experimental temporary dental cement composed of copaiba oil, white pitch, zinc oxide and stabilizers. For this purpose, a scoping review of the literature on Copaíba in Dentistry was carried out, where only one work on the subject, authored by the candidate, was found. After identifying the chemical components of copaiba oleoresin and stabilizing the formulation at room temperature, already carried out, the ideal proportion of components is sought so that the consistency of the pastes becomes easy to manipulate by the dentist. The finished cement will be tested for its solubility, acidity, film thickness and cytotoxicity (MTT and Natural Red). The detection of bioactives present in the cement after setting will also be evaluated. Then, for the mechanical test, 60 PMMA crowns made using CAD/CAM will be subjected to the tensile strength test, after cementation with the experimental cement and commercial Dycal cements (Dentsply Ltda - Petrópolis, RJ, Brazil) and Temp Bond NE (Keer Corporation - Orange, CA, USA). Twenty crowns per group will be pulled in a universal testing machine: without aging (n=10) and with aging (n=10). Aging will be carried out in a fatigue machine with a 6mm diameter metallic piston for 10,000 cycles, at 60mm/min with a load of 200N. It is expected that with the results obtained in this study, the possibility of in vivo testing with this cement will become clinically viable.Keywords: Dental materials; Dental cements; Phytotherapy; Amazon