Isolation of non-dereplicated parasitic plant metabolites in metabolomic analyses.

• Grant number: 24/15443-0
• Support Opportunities: Scholarships in Brazil - Master
• Start date: November 01, 2024
• End date: June 30, 2026
• Field of knowledge: Health Sciences - Pharmacy - Pharmacognosy
• Principal Investigator: Daniel Pecoraro Demarque
• Grantee: Mariana Tedesco Hufnagel
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 22/08191-9 - Assessing the secondary metabolites occurrence in parasitic plants and hosts, AP.JP

Abstract

The de-replication process is used in metabolomic analyses for the annotation of already identified substances. When this process cannot suggest a known chemical structure, it indicates the possibility of the presence of a potentially new structure. Thus, the present project is a continuation of the metabolomic analysis project of parasitic plants versus host plants, aiming at the isolation of substances that could not be de-replicated.