Use of serial cultures of caecal contents from adult commercial birds to prevent infection of young birds with Salmonella serotypes A, B and C

• Grant number: 24/05450-9
• Support Opportunities: Scholarships in Brazil - Master
• Start date: January 01, 2025
• End date: February 28, 2026
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Pathology
• Principal Investigator: Angelo Berchieri Junior
• Grantee: Isis Mari Miyashiro Kolososki
• Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil

Abstract

Human food-borne infection by Salmonella spp. has been a major problem in several countries, a factor that is aggravated by the emergence of antimicrobial-resistant strains. Various alternatives have been investigated, within the concept of single health, aimed at combating salmonellosis that are not harmful to animal and human health. Among the options are products made from the natural intestinal microbiota of healthy poultry to prevent the colonization of pathogens and improve nutritional gain. These actions are based on the concept of competitive exclusion developed by Nurmi & Rantala in the 1970s. However, the large-scale application of this technique is still limited by the lack of clarification about the constituents of the microbiota and the mechanisms used to optimize intestinal health. Given this, this proposal aims to verify the efficacy and microbiological constitution of competitive exclusion made from the serial dilution of caecal feces from adult birds to minimize Salmonella infection and excretion.