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Assessment of the effects of serotonin and its precursor in the development of intestinal villi and immunity of broiler chickens challenged with Salmonella Enteritidis.

Grant number: 11/15338-1
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2012
Effective date (End): February 28, 2013
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal researcher:Raphael Lucio Andreatti Filho
Grantee:Taís Cremasco Donato
Home Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


Scientific papers report a growth in foodborne infections in humans from consumption of poultry products, which led to a greater demand from government agencies and consumer market, increasing the interest in the use of natural and alternative products given to the chicken. In this context, we highlight the good results showed by probiotics. Serotonin is a biogenic monoamine, which is derived from tryptophan and participates in several functions of the gastrointestinal tract and plays an important role in the interaction between the immune, endocrine and nervous systems. In mammals, serotonin is reported with consistence, but there are few studies in birds. This study aims to investigate the effects of serotonin and its precursor, in combination or not with probiotics in the development of intestinal villi and immunity of broiler chickens challenged with Salmonella Enteritidis.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TAÍS C. DONATO; ANA ANGELITA S. BAPTISTA; BRUNA D. SMANIOTTO; KEILA C.O.D. GARCIA; ADRIANO S. OKAMOTO; JULIO L. SEQUEIRA; RAPHAEL L. ANDREATTI FILHO. Avaliação dos efeitos de 5-hidroxitriptofano em-hidroxibenzilhidrazine associados a Lactobacillus spp. na morfometria intestinal e imunomarcação de serotonina em frangos de corte desafiados com Salmonella Enteridis. Pesquisa Veterinária Brasileira, v. 35, n. 7, p. 677-684, . (11/15338-1)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
DONATO, Taís Cremasco. Ação da serotonina associada á Lactobacillus spp. na resposta imune e morfometria intestinal de frangos de corte (Gallus gallus domesticus-LINNAEUS 1758) desfiados com Salmonella enteritidis. 2013. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Medicina Veterinária e Zootecnia. Botucatu Botucatu.

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