Investigation of the mechanism of ultrasonic phosphate bond formation (LUF).

• Grant number: 25/07220-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2025
• End date: May 31, 2026
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: João Henrique Lopes
• Grantee: Letícia Bastos
• Host Institution: Divisão de Ciências Fundamentais (IEF). Instituto Tecnológico de Aeronáutica (ITA). Ministério da Defesa (Brasil). São José dos Campos , SP, Brazil
• Associated research grant: 22/03247-6 - Investigation of mesoporous nanoparticles from bioactive glasses containing niobium in bone tissue engineering, AP.PNGP.PI

Abstract

The present work plan aims to investigate the formation of the ultrasonic phosphate bonding (LUF) in bioactive glass particles through infrared spectroscopy (FTIR), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). The strategy consists of selecting three different materials that do not contain phosphorus in their chemical composition, for example, TiO¿, Nb¿O¿, and SiO¿, with the intention of analyzing the efficiency of the method in assembling a three-dimensional structure, leaving the investigation of bioactive glasses for a second stage. This approach is important to simplify the spectra and facilitate the understanding of the events that occur in the LUF method. Complementary studies using ³¹P RMN may be carried out to elucidate the mechanism.